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Fibrous Cap

The Effect of Carotid Plaque Morphology on Longitudinal Fibrous Cap Stress Levels

The Effect of Carotid Plaque Morphology on Longitudinal Fibrous Cap Stress Levels

... Background and Purpose: Rupture of vulnerable carotid atherosclerotic plaques is a major cause of stroke. Stress levels may reflect risk of rupture in patients with carotid atherosclerotic plaques. Features thought to ...

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Type 2 diabetes mellitus is associated with a lower fibrous cap thickness but has no impact on calcification morphology: an intracoronary optical coherence tomography study

Type 2 diabetes mellitus is associated with a lower fibrous cap thickness but has no impact on calcification morphology: an intracoronary optical coherence tomography study

... Recently, coronary calcification has been discussed as an additional risk factor of coronary plaque vulnerabil- ity. Specifically, investigations using computed tomogra- phy and intravascular ultrasound (IVUS) have ...

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Fibrous Cap Smooth Muscle Cells in Atherosclerotic Coronary Arteries Do Not Express Pluripotent Stem Cell Markers

Fibrous Cap Smooth Muscle Cells in Atherosclerotic Coronary Arteries Do Not Express Pluripotent Stem Cell Markers

... Rupture of coronary artery fibrous cap is a major cause of myocardial infarct [1]. Inhibition of the HMG CoA reductase enzyme and renin angiotensin system have been one of the most successful therapies in ...

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Correlation between Fissured Fibrous Cap and Contrast Enhancement: Preliminary Results with the Use of CTA and Histologic Validation

Correlation between Fissured Fibrous Cap and Contrast Enhancement: Preliminary Results with the Use of CTA and Histologic Validation

... Moreover, we also found that the amount of CPE is larger in the plaques with FFC (22.6 versus 12.9; P ⫽ .011). This can be explained by the fact that the rupture of the fibrous cap allows the blood to ...

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Modeling fibrous cap formation in atherosclerotic plaque development: stability and oscillatory behavior

Modeling fibrous cap formation in atherosclerotic plaque development: stability and oscillatory behavior

... In the following, we show simulated solutions of the system model ()-(), in which some of the parameter values have been chosen based on the work of Hao and Friedman []. Some parameters have been chosen, however, so ...

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Materials Discovery by Crystal Growth: Synthesis, Structure Determination, Magnetic, and Optical Properties of Complex Lanthanide Containing Oxides, Oxyhydroxides, and Oxyfluorides

Materials Discovery by Crystal Growth: Synthesis, Structure Determination, Magnetic, and Optical Properties of Complex Lanthanide Containing Oxides, Oxyhydroxides, and Oxyfluorides

... human fibrous cap or ...thin fibrous cap (Lawlor et ...human fibrous cap samples were carried out in order to obtain the shear modulus of a neo- Hookean model (Barrett et ...

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Relationships of coronary culprit-plaque characteristics with duration of diabetes mellitus in acute myocardial infarction: an intravascular optical coherence tomography study

Relationships of coronary culprit-plaque characteristics with duration of diabetes mellitus in acute myocardial infarction: an intravascular optical coherence tomography study

... as fibrous or lipid-rich plaques, identified as a homogeneous, highly backscattering region ...the fibrous cap with clear cavity formation ...of cap rupture in multiple adjacent frames (Fig. ...

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Intracranial Atherosclerotic Plaque Enhancement in Patients with Ischemic Stroke

Intracranial Atherosclerotic Plaque Enhancement in Patients with Ischemic Stroke

... tracranial atherosclerotic plaque has been well studied and well established.4-6 Several aspects of plaque structure, including size, wall thickness, integrity of the fibrous cap, and th[r] ...

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Cardiovascular magnetic resonance in carotid atherosclerotic disease

Cardiovascular magnetic resonance in carotid atherosclerotic disease

... commonly fibrous cap rupture (Figure ...ipsilateral fibrous cap rupture was observed in ...that cap rupture occurred more fre- quently in symptomatic patients (74%) than in asympto- ...

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High resolution intravascular magnetic resonance quantification of atherosclerotic plaque at 3T

High resolution intravascular magnetic resonance quantification of atherosclerotic plaque at 3T

... detector as a possible guidewire for identifying imaging and measuring the fibrous cap thickness of atherosclero- tic plaques in a widely-available clinical 3T MR system. In a 1-cm region (r ≤ 5 mm), ...

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Carotid artery calcification score and its association with cognitive impairment

<p>Carotid artery calcification score and its association with cognitive impairment</p>

... FCSR, fibrous cap surface rupture; IPH, intraplaque hemorrhage; LA, lumen area; LRNC, lipid- rich necrotic nucleus; MCI, mild cognitive impairment; MDCT, multi-detector row spiral CT; MMSE, Mini– Mental ...

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PubMedCentral-PMC5084842.pdf

PubMedCentral-PMC5084842.pdf

... Soft tissue dynamics in response to an impulse of acoustic radiation force were simulated using previously developed finite element method (FEM) models [29] utilizing LS-DYNA (Livermore Software Technology Corporation, ...

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Non-culprit plaque characteristics in acute coronary syndrome patients with raised hemoglobinA1c: an intravascular optical coherence tomography study

Non-culprit plaque characteristics in acute coronary syndrome patients with raised hemoglobinA1c: an intravascular optical coherence tomography study

... FCT: fibrous cap thickness; FPG: fasting plasma glucose; HbA1c: hemoglobi- nA1c; IFG: impaired fasting glucose; IGT: impaired glucose tolerance; LI: lipid index; MACEs: major adverse cardiovascular events; ...

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Association between daily glucose fluctuation and coronary plaque properties in patients receiving adequate lipid-lowering therapy assessed by continuous glucose monitoring and optical coherence tomography

Association between daily glucose fluctuation and coronary plaque properties in patients receiving adequate lipid-lowering therapy assessed by continuous glucose monitoring and optical coherence tomography

... to fibrous caps ...[11]. Fibrous cap was defined as a signal-rich homogenous layer overlying the lipid-rich plaque ...the fibrous cap was measured 3 times, and its average was defined ...

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Detection and characterization of atherosclerotic fibrous caps with T2 weighted MR

Detection and characterization of atherosclerotic fibrous caps with T2 weighted MR

... well-defined cap and atheromatous ...the fibrous cap, which places the contents of the athero- matous core in contact with the vessel lumen, thus meeting our definition of a fibrous cap ...

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Original Article Smooth muscle immaturity in the carotid arterial neointima as a prognostic marker for systemic atherogenic cardiovascular events in the Asian male

Original Article Smooth muscle immaturity in the carotid arterial neointima as a prognostic marker for systemic atherogenic cardiovascular events in the Asian male

... that at least 2 possibilities exist. First, intra- plaque leukocytes, including macrophages, secrete enzymes such as matrix metallopro- teinase, which inhibit maturation of SMCs in the same manner as the development of ...

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Predicting Carotid Plaque Characteristics Using Quantitative Color Coded T1 Weighted MR Plaque Imaging: Correlation with Carotid Endarterectomy Specimens

Predicting Carotid Plaque Characteristics Using Quantitative Color Coded T1 Weighted MR Plaque Imaging: Correlation with Carotid Endarterectomy Specimens

... and fibrous cap thickness as well as the spatial correspondence between the MR and histologic images, high-field MR imaging scanners and sophisticated 3D imaging techniques with excellent contrast (eg, ...

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A parameterized analysis of the mechanical stress for co ronary plaque fibrous caps

A parameterized analysis of the mechanical stress for co ronary plaque fibrous caps

... The fibrous cap is a protective layer of connective tissue that covers the core of an atherosclerotic ...the fibrous cap, the percentage of stenos- ed area, and the stiffness of the core were ...

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T1 Gadolinium Enhancement of Intracranial Atherosclerotic Plaques Associated with Symptomatic Ischemic Presentations

T1 Gadolinium Enhancement of Intracranial Atherosclerotic Plaques Associated with Symptomatic Ischemic Presentations

... Prior MR imaging and histopathologic studies have shown that vulnerable carotid artery atherosclerotic plaques are characterized by a ruptured fibrous cap, a lipid-rich necrotic core, an[r] ...

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Comparison of Predictive Ability of Computed Tomography and Magnetic Resonance Imaging in Patients with Carotid  Atherosclerosis Complicated with Stroke

Comparison of Predictive Ability of Computed Tomography and Magnetic Resonance Imaging in Patients with Carotid Atherosclerosis Complicated with Stroke

... unstable fibrous cap number of patients detected by CT and MRI were compared between the two ...unstable fibrous cap number detected by CT and MRI than those in the control group ...

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