filarial infections
Toward Molecular Parasitologic Diagnosis: Enhanced Diagnostic Sensitivity for Filarial Infections in Mobile Populations
... of filarial infections among individuals residing in areas where the disease is not endemic requires both strong clinical suspicion and expert training in infrequently practiced parasitological ...developed ...
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Identifying co endemic areas for major filarial infections in sub Saharan Africa: seeking synergies and preventing severe adverse events during mass drug administration campaigns
... Background: Onchocerciasis and lymphatic filariasis (LF) are major filarial infections targeted for elimination in most endemic sub-Saharan Africa (SSA) countries by 2020/2025. The current control ...
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A cross sectional study of the filarial and Leishmania co endemicity in two ecologically distinct settings in Mali
... While several mass drug administration campaigns have been implemented since 2005 in Mali, the current study sug- gests that filarial infections persist regardless of previous implementations. Furthermore, ...
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ST2 Deficiency Does Not Impair Type 2 Immune Responses during Chronic Filarial Infection but Leads to an Increased Microfilaremia Due to an Impaired Splenic Microfilarial Clearance
... Similar to the cytokine milieu within the thoracic cavity, the cellular composition in the thoracic cavity was not altered by the loss of the ST2 receptor during L. sigmodontis infection. However, total thoracic cavity ...
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Interleukin-10- and Transforming Growth Factor β-Independent Regulation of CD8+ T Cells Expressing Type 1 and Type 2 Cytokines in Human Lymphatic Filariasis
... to filarial infections are not well de- ...in filarial infections, we examined the frequencies of these cells in clinically asymptomatic, patently infected (INF) individuals, directly ex vivo ...
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Morphometric analyses of canine blood microfilariae isolated by the Knott’s test enables Dirofilaria immitis and D repens species specific and Acanthocheilonema (syn Dipetalonema) genus specific diagnosis
... The morphometric analysis proved to be a very useful, quick and inexpensive diagnostic tool and it represents the first step in the diagnosis of filarial infections. How- ever, the discrimination between ...
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Decreased nematode clearance & anti-phosphorylcholine specific IgM responses in mannose-binding lectin deficient mice
... lymphatic filarial infection. Indeed, gain of new filarial infections over a 30-year period are 10-fold higher in people with low, compared to high, MBL-expression ...of filarial and bacterial ...
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Cytokine regulation of antigen driven immunoglobulin production in filarial parasite infections in humans
... with filarial infections, with a focus on the role of interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) in the generation and regulation of the ...
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Killing filarial nematode parasites: role of treatment options and host immune response
... human filarial infections are well documented, the host immune determinants ...as filarial nematodes, are currently not well defined, and remain elusive ...of filarial nematodes, the innate ...
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A rare case of giant leiomyosarcoma in a filarial scrotum: a case report
... Filariasis in advance stages may evolve into scrotal lym- phedema and scrotal elephantiasis. In 1948 Stewart and Treves first described the association of chronic lymphe- dema with lymphangiosarcoma [6]. ...
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Rapid, Novel, Specific, High Throughput Assay for Diagnosis of Loa loa Infection
... in filarial infections can increase specificity (8, 14), no increase in sensitivity or specificity was found by measuring anti-IgG4 levels compared with total IgG levels in the LIPS for- ...
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Filarioid infections in wild carnivores: a multispecies survey in Romania
... of the canine host and is associated with a variety of dermatological conditions [3, 4] and, more recently, O. lupi , which is localized in the connective tissue of the sclera or in the retrobulbar regions of the eye of ...
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Nematode Asparaginyl-tRNA Synthetase Resolves Intestinal Inflammation in Mice with T-Cell Transfer Colitis
... helminth infections in humans ...the filarial protease inhibitor cystatin (4), the Toll-like receptor response to filarial glycoprotein ES-62 (25), the effects of Schistosoma mansoni egg glycoprotein ...
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Examining the role of macrolides and host immunity in combatting filarial parasites
... In individual dogs infected with D. immitis, a single dose of ML can lead to extended amicrofilaremia, but more typically, this is not the case. Since adult D. immitis res- ide in the pulmonary arteries and microfilariae ...
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Chiluria in a lymphatic filariasis endemic area
... of filarial infections and are able to detect microfilariae and/or their antigens in peripheral blood, besides the possibility of using ultrasound to identify adult worms in lymphatic vessels ...with ...
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Development of filarial vaccine by targeting stage specific proteins
... B. malayi infects only certain host species, among them the jird, which has been used as a model for human filariasis [13]. We immunized jirds with four doses of ALT-1 and challenged them with 300 live L3. Four weeks ...
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Loiasis in an Expatriate American Child: Diagnostic and Treatment Difficulties
... Loiasis in an Expatriate American Child: Diagnostic and Treatment Difficulties.. Eight filarial nematodes cause disease in man,.[r] ...
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Interleukin 1 (IL-1)- and IL-23-Mediated Expansion of Filarial Antigen-Specific Th17 and Th22 Cells in Filarial Lymphedema
... in filarial lymphedema. Since Th17 FIG 2 Filarial lymphedema is associated with higher baseline and antigen-stimulated frequencies of Th17 and Th22 ...
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Filarial infection influences mosquito behaviour and fecundity
... Understanding vector-parasite interactions is increasingly important as we move towards the endpoint goals set by the Global Programme for the Elimination of Lymphatic Filariasis (GPELF), as interaction dynamics may ...
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Giant filarial retroperitoneal cyst: a diagnostic dilemma
... Case presentation: We report a case of a huge retroperitoneal cystic mass in a 46-year-old patient who presented with a long-standing, painless progressive abdominal swelling. On examination, there was a large, ...
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