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Flupirtine Maleate

Concise review: Therapeutic potential of flupirtine maleate

Concise review: Therapeutic potential of flupirtine maleate

... properties. Flupirtine is a centrally acting analgesic but the analgesic action of flupirtine does not depend on any central opioid ...of flupirtine is not reduced by the opioid antagonistic drug ...

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NOVEL APPLICATION OF MIXED HYDROTROPIC SOLUBILIZATION TECHNIQUE IN THE FORMULATION AND EVALUATION OF SOLID DISPERSION OF FLUPIRTINE MALEATE

NOVEL APPLICATION OF MIXED HYDROTROPIC SOLUBILIZATION TECHNIQUE IN THE FORMULATION AND EVALUATION OF SOLID DISPERSION OF FLUPIRTINE MALEATE

... The solid dispersions of flupirtine maleate were developed using the concept of mixed hydrotropic solubilization technique. Solid dispersions containing blend of niacinamide and sodium benzoate as water- ...

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Development and Validation of Stability Indicating RP-HPLC Method for Simultaneous Estimation of Paracetamol and Flupirtine maleate in Pure and Pharmaceutical Dosage Forms

Development and Validation of Stability Indicating RP-HPLC Method for Simultaneous Estimation of Paracetamol and Flupirtine maleate in Pure and Pharmaceutical Dosage Forms

... and Flupirtine Maleate in combined- dosage ...and Flupirtine Maleate were ...and Flupirtine Maleate were found to be ...and Flupirtine Maleate in formulations was ...

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METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS DETERMINATION OF FLUPIRTINE MALEATE AND PARACETAMOL BY RP – HPLC TECHNIQUE

METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS DETERMINATION OF FLUPIRTINE MALEATE AND PARACETAMOL BY RP – HPLC TECHNIQUE

... of Flupirtine maleate and ...of Flupirtine maleate and Paracetamol in the commercial tablet dosage form is within the pharmacopoeial ...of Flupirtine maleate and Paracetamol in ...

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Development and Validation of RP-HPLC Method for the Simultaneous Estimation of Paracetamol and Flupirtine Maleate in Pharmaceutical Dosage Form

Development and Validation of RP-HPLC Method for the Simultaneous Estimation of Paracetamol and Flupirtine Maleate in Pharmaceutical Dosage Form

... and flupirtine maleate (1 mg/ml) were prepared separately using methanol as sol- ...of flupirtine maleate were prepared by diluting with mobile ...and flupirtine maleate were ...

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Non Ionic Surfactant Based Vesicles (Niosomes) Containing Flupirtine Maleate as an Ocular Drug Delivery System

Non Ionic Surfactant Based Vesicles (Niosomes) Containing Flupirtine Maleate as an Ocular Drug Delivery System

... of Flupirtine Maleate reduced number of eye wiping and ...that Flupirtine Maleate loaded niosome is possessing prolong antinociception activity and improve permeation rate as compared to pure ...

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Method Development and Validation of Paracetmol and Flupirtine Maleate by RP-HPLC

Method Development and Validation of Paracetmol and Flupirtine Maleate by RP-HPLC

... flupiritine maleate in ...flupiritine maleate were found to be linear in the concentration ranges of 5–15 µg/mL and ...flupiritine maleate confirming that the projected method is ...and ...

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DEVELOPMENT OF NEW ANALYTICAL METHODS FOR THE ESTIMATION OF FLUPIRTINE MALEATE IN BULK AND IN FORMULATIONS

DEVELOPMENT OF NEW ANALYTICAL METHODS FOR THE ESTIMATION OF FLUPIRTINE MALEATE IN BULK AND IN FORMULATIONS

... Two simple, sensitive, specific UV - spectroscopic and RP-HPLC methods are developed for the estimation of Flupirtine Maleate in bulk and pharmaceutical formulation. The first method was based on UV – ...

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Bioequivalence study of two formulations of flupirtine maleate capsules in healthy male Chinese volunteers under fasting and fed conditions

Bioequivalence study of two formulations of flupirtine maleate capsules in healthy male Chinese volunteers under fasting and fed conditions

... of flupirtine, and the T max is prolonged, and the C max is ...of flupirtine after ...take flupirtine in an empty stomach because of its faster absorption rate and complete absorption, which mean ...

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“Flupirtine: A Review on its Therapeutic Potency” by Syeda Khair-ul-Bariyah, Muhammad Tahman Shahid, Pakistan.

“Flupirtine: A Review on its Therapeutic Potency” by Syeda Khair-ul-Bariyah, Muhammad Tahman Shahid, Pakistan.

... slice cultures (OHSCs) exposed to N-methyl- D-aspartate (NMDA), oxygen and glucose deprivation along with reoxygenation (OGD) or serum withdrawal (SW). The most probable susceptible region to NMDA and OGD-induced ...

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The indirect NMDAR inhibitor flupirtine induces sustained post- ischemic recovery, neuroprotection and angioneurogenesis

The indirect NMDAR inhibitor flupirtine induces sustained post- ischemic recovery, neuroprotection and angioneurogenesis

... with flupirtine reduced calpain activity (Figure ...with flupirtine, however, reversed the aforementioned effects, ...by flupirtine as well (Figure ...that flupirtine indirectly exerts ...

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Sarcosinium maleate at 123 K

Sarcosinium maleate at 123 K

... The packing of molecules of (I) within the unit cell, viewed down the b axis is shown in Fig 2. The sarcosinium and semi-maleate ions which are linked by O—H···O and N—H···O hydrogen bonds, aggregate into ...

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METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF ARTEROLANE MALEATE AND PIPERAQUINE PHOSPHATE BY RP HPLC

METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF ARTEROLANE MALEATE AND PIPERAQUINE PHOSPHATE BY RP HPLC

... Arterolane maleate and Piperaquine phosphate and to validate the method according to USP and ICH guidelines and applying the same for its estimation in pharmaceutical ...

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Efficacy and tolerability of fixed-combination bimatoprost/timolol versus fixed-combination dorzolamide/brimonidine/timolol in patients with primary open-angle glaucoma or ocular hypertension: a multicenter, prospective, crossover study

Efficacy and tolerability of fixed-combination bimatoprost/timolol versus fixed-combination dorzolamide/brimonidine/timolol in patients with primary open-angle glaucoma or ocular hypertension: a multicenter, prospective, crossover study

... Bim/tim: bimatoprost 0.03% and timolol maleate 0.5%; dorz/brim/ tim: dorzolamide 2%, brimonidine 0.2%, and timolol maleate 0.5%; IOP: intraocular pressure; OHT: ocular hypertension; OSDI[r] ...

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Understanding unconventional routes to impurities from drugs in hydrolytic conditions

Understanding unconventional routes to impurities from drugs in hydrolytic conditions

... Diclofenac, flupirtine and quinapril degrade to cyclized products, and formation of these products are reported to occur through formation of an amide bond between a carboxylic acid[r] ...

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A comparative study of efficacy and safety of flupirtine versus piroxicam in postoperative pain in patients undergoing lower limb surgery

A comparative study of efficacy and safety of flupirtine versus piroxicam in postoperative pain in patients undergoing lower limb surgery

... Background: Effective control of pain postoperatively is essential in providing enhanced patient care and a cost-effective hospital stay. Though many treatment modalities exist for postoperative pain management in ...

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2 Carb­­oxy­pyridinium maleate

2 Carb­­oxy­pyridinium maleate

... Data collection: APEX2 Bruker, 2004; cell refinement: SAINT Bruker, 2004; data reduction: SAINT; programs used to solve structure: SHELXS97 Sheldrick, 2008; programs used to refine struc[r] ...

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Crystal structure of levomepromazine maleate

Crystal structure of levomepromazine maleate

... Levomepromazine maleate is a type of tranquilizer that is widely used as an important active pharmaceutical ingredient ...its maleate salt, we report here the crystal structure of this compound and compare ...

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ORAL DISSOLVING FILMS OF CHLORPHENIRAMINE MALEATE

ORAL DISSOLVING FILMS OF CHLORPHENIRAMINE MALEATE

... Present study reveals that maximum all formulated films showed satisfactory film parameters. Formulation with HPMC E3 has shown better in vitro dissolution profile compared with other formulations. Finally oral fast ...

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DL Threoninium maleate at 150 K

DL Threoninium maleate at 150 K

... glycinium maleate (Rajagopal, Krishnakumar, Mostad & Natarajan, 2001), -alaninium maleate (Rajagopal, Krishna- kumar & Natarajan, 2001), sarcosinium maleate (Rajagopal et ...l-alaninium ...

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