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focal ischemic cerebral injury

Focal Ischemic Cerebral Injury in the Newborn: Diagnosis by Ultrasound and Correlation with Computed Tomographic Scan

Focal Ischemic Cerebral Injury in the Newborn: Diagnosis by Ultrasound and Correlation with Computed Tomographic Scan

... The focal areas of increased echodensity seen on ultrasound scan cor- respond to the appearance on CT scan of areas of decreased density which are known to represent ischemic cerebral Fu[r] ...

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Adiponectin: a pivotal role in the protection against cerebral ischemic injury

Adiponectin: a pivotal role in the protection against cerebral ischemic injury

... reported that adiponectin could promote focal angiogenesis in cerebral ischemic injury. They showed that after MCAO mice receiving intracerebral injection of adeno-associated viral vector ...

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Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

... an ischemic brain ...of ischemic stroke, and provides a general model of ...of cerebral ischemic injury is explained, and experimental animal models of global and focal ...

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Original Article Activation of STAT3 is involved in neuronal apoptosis in focal cerebral ischemia/reperfusion rats via Bcl 2/Fas pathway

Original Article Activation of STAT3 is involved in neuronal apoptosis in focal cerebral ischemia/reperfusion rats via Bcl 2/Fas pathway

... the ischemic core and the ischemic penumbra region after ...of cerebral ischemia in rats reveal that dysregulation of the Bcl-2 family of proteins can exacerbate ischemic neuronal ...oxidative ...

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Original Article Mild hypothermia combined with isoflurane post-treatment alleviates cerebral ischemia reperfusion injury in rats through inhibition of STAT3 activation

Original Article Mild hypothermia combined with isoflurane post-treatment alleviates cerebral ischemia reperfusion injury in rats through inhibition of STAT3 activation

... in cerebral I/R injury. It was found that focal cerebral ischemia would activate JAK- STAT signaling pathway in the post-ischemic brain, predominantly in the macrophages/ microglia, and ...

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Original Article Combination treatment with breviscapine and netrin-1 suppresses permanent focal cerebral ischemic injury by activating PGE2 receptor

Original Article Combination treatment with breviscapine and netrin-1 suppresses permanent focal cerebral ischemic injury by activating PGE2 receptor

... system injury, there are many down- stream events known as “secondary injury” that ends up with progressive axonal degenera- tion [12, ...(I/R) injury [14]; so we hypothesized that it has been ...

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The choroid plexus as a site of damage in hemorrhagic and ischemic stroke and its role in responding to injury

The choroid plexus as a site of damage in hemorrhagic and ischemic stroke and its role in responding to injury

... CP injury after focal ischemia [76–79] ...middle cerebral artery (MCA) occlusion can result in reduced blood supply to the LVCP [76] as the branch point for the AChA from the internal carotid artery ...

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The neuroprotective mechanisms of ginkgolides and bilobalide in cerebral ischemic injury: a literature review

The neuroprotective mechanisms of ginkgolides and bilobalide in cerebral ischemic injury: a literature review

... acute ischemic stroke has been constrained to a relatively small patient population (less than 5%) (Sifat et ...acute ischemic stroke, the most feared complication is symptomatic intracerebral hemorrhage ...

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Attenuation of Focal Cerebral Ischemic Injury Following Post-Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat

Attenuation of Focal Cerebral Ischemic Injury Following Post-Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat

... brain injury is resulting from a complex sequence of pathophysiological events that is developed with time and space ...of focal cerebral ischemia [2]. Ischemic brain edema occurring during ...

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Electroacupuncture preconditioning reduces cerebral ischemic injury via BDNF and SDF 1α in mice

Electroacupuncture preconditioning reduces cerebral ischemic injury via BDNF and SDF 1α in mice

... following cerebral ischemia ...that focal cerebral ischemia causes an increase in endothelial SDF- 1α expression in regions adjacent to the infarcted area ...the ischemic brain, thereby ...

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CEREBRAL ISCHEMIC REPERFUSION INJURY AND NEUROPROTECTIVE ACTIVITY OF HERBAL DRUGS

CEREBRAL ISCHEMIC REPERFUSION INJURY AND NEUROPROTECTIVE ACTIVITY OF HERBAL DRUGS

... histologic injury in which specific neuronal populations are affected (selective ischemic necrosis) [9-11] ...brain injury from influx of neutrophils and to increases in reactive oxygen species ...

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Original Article Bumetanide protects focal cerebral ischemia-reperfusion injury in rat

Original Article Bumetanide protects focal cerebral ischemia-reperfusion injury in rat

... In ischemic conditions, particularly after oxygen glucose deprivation in hippocampal slices [9] and in in vivo models of global ischemia [10], KCC2 is generally down-regulated while NKCC1 is ...

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Neuroprotective effects of curdione against focal cerebral ischemia reperfusion injury in rats

Neuroprotective effects of curdione against focal cerebral ischemia reperfusion injury in rats

... in ischemic cortex at 14 days after MCAO. Results showed that MCAO injury decreased the activities of SOD, CAT and GSH-PX significantly compared to the sham ...the injury with cerebral ...

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Function and mechanism of toll-like receptors in cerebral ischemic tolerance: from preconditioning to treatment

Function and mechanism of toll-like receptors in cerebral ischemic tolerance: from preconditioning to treatment

... the cerebral ischemic injury of the central nervous sys- ...in focal MCAO were significantly re- duced ...whole cerebral ischemia model further confirmed that the cerebral ...

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Tomato, a Potential Yin Food, Protects against Stroke

Tomato, a Potential Yin Food, Protects against Stroke

... found ischemic stroke is focal cerebral ...middle cerebral artery occlusion occurred in 10% - 15% of stroke ...The cerebral ischemia has been characterized by a rapid onset of neu- ...

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receptor antagonist, on chronic brain injury after focal cerebral ischemia in rats

receptor antagonist, on chronic brain injury after focal cerebral ischemia in rats

... neuronal injury such as astrocytosis and microgliosis after focal cerebral ischemia in rats, and intracerebroventricular injection of HAMI 3379, a selective CysLT 2 R antago- nist, protects against ...

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Effects of progesterone on brain infarct size and locomotor activity in transient focal cerebral ischemic male rats

Effects of progesterone on brain infarct size and locomotor activity in transient focal cerebral ischemic male rats

... Human studies have shown that the incidence of stroke in premenopausal women is lower than that in the same age men, and it is well known that the incidence of cerebrovascular accidents rapidly increases in women after ...

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A Stable Focal Cerebral Ischemia Injury Model in Adult Mice: Assessment Using 7T MR Imaging

A Stable Focal Cerebral Ischemia Injury Model in Adult Mice: Assessment Using 7T MR Imaging

... MATERIALS AND METHODS: One hundred twenty adult mice were randomly divided into 10 groups of 12 each to respectively undergo intraluminal suture occlusion, with suture insertion depths from 0.8 cm to maximum; ...

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Neuroplastic Changes Following Brain Ischemia and their Contribution to Stroke Recovery: Novel Approaches in Neurorehabilitation

Neuroplastic Changes Following Brain Ischemia and their Contribution to Stroke Recovery: Novel Approaches in Neurorehabilitation

... post injury, followed by an increase in the ipsilesional one (3–6 ...2001). Focal stroke targeted in the somatosensory cortex (SSC) induced a transient but consistent increase of basal metabolism and field ...

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Methylene Blue Reduces Acute Cerebral Ischemic Injury via the Induction of Mitophagy

Methylene Blue Reduces Acute Cerebral Ischemic Injury via the Induction of Mitophagy

... ACI injury, we first measured the effect of MB on mitophagy in an OGD model to simulate ACI injury in ...ACI injury was al- tered after mitophagy was ...

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