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Gene Expression Profile

Gene Expression Profile, Androgen Independence and Prostate Cancer

Gene Expression Profile, Androgen Independence and Prostate Cancer

... of gene expression, through yet unclear signalling pathways results in various molecular and cel- lular changes which may independently and synergisti- cally induce transformation to androgen resistant ...

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Gene expression profile in obesity and type 2 diabetes mellitus

Gene expression profile in obesity and type 2 diabetes mellitus

... study gene expression profiles in subjects who have obesity and type 2 diabetes mellitus with and without family history to know the role of genetics in the pathobiology of these two ...performed ...

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THE CURRENT SCREENING TECHNOLOGIES OF GENE EXPRESSION PROFILE IN DIABETES MELLITUS

THE CURRENT SCREENING TECHNOLOGIES OF GENE EXPRESSION PROFILE IN DIABETES MELLITUS

... the gene expression in a patient within insulin resistant in respond to fish oil (omega-3) ...RNA expression of the kidney from diabetic rat ...on gene expression profiling in T2DM ...

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Eotaxin 3 and a uniquely conserved gene expression profile in eosinophilic esophagitis

Eotaxin 3 and a uniquely conserved gene expression profile in eosinophilic esophagitis

... other gene products) by resident cells within the ...eosinophil-derived gene products were present in the EE transcript signature; major basic protein (MBP) ...a gene that is strongly overexpressed ...

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GENE EXPRESSION PROFILE OF ETHANOL-STRESSED YEAST IN THE PRESENCE OF ACETALDEHYDE

GENE EXPRESSION PROFILE OF ETHANOL-STRESSED YEAST IN THE PRESENCE OF ACETALDEHYDE

... HXT gene family. The HXT gene family comprises seven isogenes (HXT1, 2, 3, 4, 5, 6, and ...HXT4 gene has increased expression levels in the presence of low glucose concentrations, and to be ...

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Use of serial analysis of gene expression to reveal the specific regulation of gene expression profile in asthmatic rats treated by acupuncture

Use of serial analysis of gene expression to reveal the specific regulation of gene expression profile in asthmatic rats treated by acupuncture

... of gene expression (SAGE), may help to reveal and clarify the pos- sible mechanism of ...powerful expression profiling method and much more accessible for dissecting the complex system, was applied ...

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Rap1 Relocalization Contributes to the Chromatin-Mediated Gene Expression Profile and Pace of Cell Senescence

Rap1 Relocalization Contributes to the Chromatin-Mediated Gene Expression Profile and Pace of Cell Senescence

... facilitate gene activation by the Gcn4 transcription factor, which by itself cannot function efficiently at binding site ensconced within a nucleosome (Yu and Morse 1999), and experimental depletion of Rap1 leads ...

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Comprehensive analysis of gene-expression profile in chronic obstructive pulmonary disease

Comprehensive analysis of gene-expression profile in chronic obstructive pulmonary disease

... Results: A total of 39 up- and 15 downregulated DEGs were screened. Most of the upregulated genes were involved in the immune response process, while the downregulated genes were involved in the steroid metabolic ...

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Exploring the Key Genes and Pathways of Osteoarthritis in Knee Cartilage in a Rat Model Using Gene Expression Profiling

Exploring the Key Genes and Pathways of Osteoarthritis in Knee Cartilage in a Rat Model Using Gene Expression Profiling

... Knee cartilage samples were collected from individual male Wistar rats with monosodium iodoacetate (MIA)-induced OA (0, 2, 14, and 28 days after treatment). MIA-treated (3 mg) ani- mals were compared to intact controls. ...

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Computational discovery of therapeutic candidates for preventing preterm birth

Computational discovery of therapeutic candidates for preventing preterm birth

... disease gene expression profiles to identify potential new treatments for ...The Gene Expression Omnibus (GEO), which was created in an effort to make high-throughput gene ...

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Basal like phenotype is not associated with patient survival in estrogen receptor negative breast cancers

Basal like phenotype is not associated with patient survival in estrogen receptor negative breast cancers

... 0.19). Gene expression profiles of immunohistochemically determined CK5/14-positive tumors within the ER-negative tumor group implicated 1,713 differently expressed genes (p < ...published gene ...

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Unbiased analysis of the impact of micropatterned biomaterials on macrophage behaviour provides insights beyond pre defined polarisation states

Unbiased analysis of the impact of micropatterned biomaterials on macrophage behaviour provides insights beyond pre defined polarisation states

... and gene expression profile were assessed using conventional methods (morphology, cytokine profile, surface marker expression, phagocytosis) and gene ...distinct gene ...

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A functional profile of gene expression in ARPE-19 cells

A functional profile of gene expression in ARPE-19 cells

... the gene expression profile of these cells, which will than lay the foundation for further molecular characterization of RPE cells in both normal and diseased ...

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Reduced H3K27me3 leads to abnormal Hox gene expression in neural tube defects

Reduced H3K27me3 leads to abnormal Hox gene expression in neural tube defects

... Hox gene expression induced by RA during neural tube development To define alterations in gene expression profile accompa- nying RA-induced morphology changes, RNA-Seq was performed on ...

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Explore the Potential Mechanism of Bufadienolides-Like Chemicals on Breast Cancer through Bioinformatics Analysis

Explore the Potential Mechanism of Bufadienolides-Like Chemicals on Breast Cancer through Bioinformatics Analysis

... During the process of DEGs selection with relative enrichment sets, the gene expression profile 311. was first transformed into the prior knowledge gene set of c2BroadSets and[r] ...

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Expression Profile of Cell Cycle-related Genes in Human Fibroblasts Exposed Simultaneously to Radiation and Simulated Microgravity

Expression Profile of Cell Cycle-related Genes in Human Fibroblasts Exposed Simultaneously to Radiation and Simulated Microgravity

... changes in gene expression profile due to the combined effect in genes involved in the cell cycle. 292[r] ...

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Characterization of EDP-305, a Highly Potent and Selective Farnesoid X Receptor Agonist, for the Treatment of Non-alcoholic Steatohepatitis

Characterization of EDP-305, a Highly Potent and Selective Farnesoid X Receptor Agonist, for the Treatment of Non-alcoholic Steatohepatitis

... anti-inflammatory gene signatures in human macrophage and stellate cell lines, as well as favorable effects on lipid metabolism in hepatocytes, including enhanced low density lipoprotein (LDL)-cholesterol uptake ...

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Screening of feature genes of the ovarian cancer epithelia with DNA microarray

Screening of feature genes of the ovarian cancer epithelia with DNA microarray

... the gene expression profile between ovarian surface epithelia (OSE) and laser capture microdissected serous ovarian cancer epithelia (CEPI) ...using gene ontology (GO), molecular pathway, and ...

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Irreversible dual inhibitory mode: the novel Btk inhibitor PLS- 123 demonstrates promising anti-tumor activity in human B-cell lymphoma

Irreversible dual inhibitory mode: the novel Btk inhibitor PLS- 123 demonstrates promising anti-tumor activity in human B-cell lymphoma

... ibrutinib. Gene expression profile analysis further suggested that the different selectivity profile of PLS-123 led to significant downregulation of oncogenic gene PTPN11 ...

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Heat shock genes in the stingless bee Melipona interrupta (Hymenoptera, Meliponini)

Heat shock genes in the stingless bee Melipona interrupta (Hymenoptera, Meliponini)

... The gene expression profile of HSP60 in insects is not as commonly studied as those of HSP70 and 90 because the expression of this protein cannot be induced by heat stress in certain species ...

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