Genetic Regulatory Networks
Approximation of state variables for discrete time stochastic genetic regulatory networks with leakage, distributed, and probabilistic measurement delays: a robust stability problem
... in genetic regulatory networks (GRNs) has gained significance in both biological and bio-medical sciences, and a huge number of tremendous results have been ...
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Robust stability of interactional genetic regulatory networks with reaction diffusion terms
... these genetic regulatory networks (GRNs), which are considered as important sub- module of complex biology network, because a GRN can clarify the mechanism of biologi- cal ...of genetic ...
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Desired clustering of genetic regulatory networks with mixed delays
... In this study, we propose two techniques for clustering genetic regulatory networks with mixed delays. Laws for identifying coupling parameters are designed, and the Lyapunov theorem and Lipschitz ...
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Computational approaches for modelling intrinsic noise and delays in genetic regulatory networks
... regulatory networks. We address these aspects by focusing on genetic regulatory networks that share a common network motif, namely the negative feedback loop, leading to oscillatory ...
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On the Stability of Piecewise Genetic Regulatory Networks
... uncertain genetic regulatory networks,” International Journal of Robust and Nonlinear Control, ...of genetic regulatory networks: nutritional stress response in Escherichia ...
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Exponential stability of impulsive stochastic genetic regulatory networks with time varying delays and reaction diffusion
... We present a mean-square exponential stability analysis for impulsive stochastic genetic regulatory networks (GRNs) with time-varying delays and reaction-diffusion driven by fractional Brownian motion ...
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A novel data-driven Boolean model for genetic regulatory networks
... within the tolerated time period or Off (0) at time t +1 when the tolerated time period is expired regardless of the gene state of σ i at time t. We assume that the tolerated time period for protein decay has only one ...
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Modelling the evolution of genetic regulatory networks
... random networks and scale-free networks in terms of their degree ...a genetic algorithm, with selection acting on a range of properties from gene number and degree of connectivity through periodic ...
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Equivalent genetic regulatory networks in different contexts recover contrasting spatial cell patterns that resemble those in Arabidopsis root and leaf epidermis: a dynamic model
... the genetic networks regulating their respective cell-fate determina- tion have very similar structures and ...leaf networks, these have equivalent dynamical ...conserved genetic network ...
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Buffering of Genetic Regulatory Networks in Drosophila melanogaster
... This study explores whether an allelic imbalance in an interspecific population of D. melanogaster differs by environ- ment and whether regulatory variation equally involves cis- and trans-effects. Consistent with ...
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Metabolite Changes Signal Genetic Regulatory Mechanisms for Robust Cell Behavior
... IMPORTANCE Metabolite accumulation can create adverse intracellular conditions that are relieved by compensatory immediate changes of metabolite pools and later changes of transcript levels. It has been known that gene ...
8
From Faulty Biochemical Assumptions to Poor Diagnostic Performance: Reflections on the Failure of DNA Microarrays to Become a Reliable Clinical Diagnostic Tool
... Since their introduction into laboratory practice, the microarray measurements have been termed gene expression profiling, and this term has been used interchangeably with transcription profiling. When using such ...
12
Fan-out in gene regulatory networks
... In this manuscript, an experimental estimation method for the fan-out is proposed. This method is based on a linear relationship between a certain prop- erty of a module (response time) and the amount of load from ...
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Visualizing regulatory interactions in metabolic networks
... of regulatory interactions in a given metabolic network is based on a novel concept defining the RS of effectors regulating cer- tain reaction ...this regulatory information has never been repre- sented ...
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The effects of European regulatory networks on the bureaucratic autonomy of national regulatory authorities
... As regards rule-enforcement activities, bureaucratic autonomy firstly relates to the extent to which a regulator can act with relative discretion when putting a legal framework into practice, i.e. during the act of ...
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Modeling of gene regulatory networks: A review
... The most basic and simplest modeling methodology is discrete and logic-based, and was introduced by Kauff- man and Thomas [8,9]. The reconstruction of the regula- tory network that controls the development of sea urchin ...
9
PubMedCentral-PMC4845796.pdf
... makes genetic accommodation possi- ble (Moczek, 2007; Moczek et ...cryptic genetic variation, both be- cause the effects of novel genetic variants are buffered by com- pensatory plastic responses ...
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Evolution of Developmental Gene Regulatory Networks in Echinoids
... numerous regulatory states in the ...50 regulatory factors that execute hundreds of experimentally-validated regulatory transactions (Peter, Faure, and Davidson, ...developmental regulatory ...
183
Genomic cis regulatory networks in the early Ciona intestinalis embryo
... gene regulatory networks, in which genes exert their effects in a sequential and combinatorial manner (Levine and Davidson, ...gene regulatory networks responsible for developmental ...and ...
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Identification of Prognostic Biomarker Signatures and Candidate Drugs in Colorectal Cancer: Insights from Systems Biology Analysis
... transcriptional/post-transcriptional regulatory networks to identify reporter signaling and regulatory molecules; utilized functional overrepresentation and pathway enrichment analyses to elucidate ...
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