glial-derived neurotrophic factor
Dynamics of neural stem cell mediated neuroprotection in the presence of oxidative stress: studies in vitro and in vivo
... One group of such developmental molecules are neurotrophic factors like, neurotrophic 3,4 & 5 NT-3, 4 & 5, brain derived neurotrophic factor BDNF, glial derived neurotrophic factor GDNF,[r] ...
155
RET mediated glial cell line derived neurotrophic factor signaling inhibits mouse prostate development
... understood. Glial cell line-derived neurotrophic factor (GDNF) binds GDNF family receptor α 1 (GFR α 1) and signals through activation of RET tyrosine ...
12
Neurotrophic actions of GDNF and neurturin in the developing avian nervous system and cloning and expression of their receptors
... known neurotrophic factors is constantly ...nerve-growth factor (NGF) (Levi-Montalcini and Hamburger, 1951), brain-derived neurotrophic factor (BDNF) (Barde ...ciliaiy ...
235
Increased antiparkinson efficacy of the combined administration of VEGF- and GDNF-loaded nanospheres in a partial lesion model of Parkinson’s disease
... as glial cell line-derived neurotrophic factor (GDNF) and vascular endothelial growth factor (VEGF), as neuroregenerative approaches that will prevent the neurodegenerative process in ...
11
Changes in cerebral autoregulation and blood biomarkers after remote ischemic preconditioning
... brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), β-nerve growth factor, ciliary neurotrophic factor, and ...
14
The role of glial cell line-derived neurotrophic factor signalling pathway in mammalian organogenesis
... inducing factor(s) present in the embryonic spinal cord, the most potent tissue inducer o f nephron formation in vitro, has been shown to not be freely soluble (Herzlinger et ...
182
Role of GDNF in Spinal Cord Injury Repair
... Keywords: Spinal cord injury, glial cell line-derived neurotrophic factor (GDNF), GFRα-1, cRET, 19.. Schwann cells, Astrogliosis, neuroprotection, axonal regeneration, comb[r] ...
12
Upregulation of mesencephalic astrocyte-derived neurotrophic factor in glial cells is associated with ischemia-induced glial activation
... CHOP, also known as growth arrest-inducible and DNA damage-inducible gene 153 (GADD153), is the proapoptotic protein that mediates ER stress-induced apoptosis [14]. CHOP has been reported to play a pivotal role in ...
13
Spermatogonial Stem Cells: A Review of Essential Factor for Self-Renewal and Differentiation
... growth factor; EGF: Epidermal growth factor; ETV5: Ets variant gene 5; GDNF: Glial cell-derived neurotrophic factor; GnRh: gonadotropin-releasing hormone; FGF2: Fibroblast growth ...
6
Histamine upregulates the expression of histamine receptors and increases the neuroprotective effect of astrocytes
... of neurotrophic factors such as glial cell-derived neuro- trophic factor (GDNF), brain-derived neurotrophic factor (BDNF), and neurotrophin-3 (NT-3) can promote neur- onal ...
10
Genetic and Epigenetic of Medullary Thyroid Cancer
... ganglioneuromatosis [32] ; patients with just FMTC individually develop MTC [29,32] . In fact proto- oncogene RET germline mutations is presented in 90% of patients with hereditary MTC (FMTC, MEN 2A, or MEN 2B) [33] . ...
9
Immunohistochemical Localization of Some Neurotrophic Factors and Their Receptors in the Rat Carotid Body
... and neurotrophic factors have been established as signaling molecules played an important role in the development of the ...some neurotrophic factors and their corre- sponding receptors in this organ by ...
6
Original Article Pulsed magnetic field promotes proliferation and neurotrophic genes expression in Schwann cells in vitro
... of neurotrophic factors in ...of neurotrophic factors in SCs was assayed by RT-PCR and ...brain-derived neurotrophic factor (BDNF), glial cell derived neurotrophic ...
11
Glial cell line-derived neurotrophic factor gene delivery via a polyethylene imine grafted chitosan carrier
... recombinant glial cell line-derived neurotrophic factor (GDNF) have been shown to protect adult nigral dopaminergic ...naturally derived material that has been used for gene ...
12
Dietary fats promote functional and structural changes in the median eminence blood/spinal fluid interface—the protective role for BDNF
... brain-derived neurotrophic factor, CTR control fed chow, GFAP glial fibrillary acidic protein, IGFBP2 insulin-like growth factor-binding protein 2, HFD high-fat diet, wk ...
18
CSF and blood biomarkers in amyotrophic lateral sclerosis: protocol for a systematic review and meta-analysis
... (PGRN), glial fibrillary acidic protein (GFAP), monocyte chemoattractant protein-1 (MCP-1), brain-derived neurotrophic factor (BDNF), TAR DNA-binding protein-43 (TDP43), YKL-40, and CHIT1 in ...
5
Serum brain derived neurotrophic factor levels and personality traits in patients with major depression
... The present study demonstrated that there was an inverse relationship between serum BDNF levels and scores for the SD personality trait in patients with MDD. In terms of the association between peripheral BDNF levels and ...
6
The Development of Treatment for Parkinson’s Disease
... anti-inflammatories, neurotrophic factors, DBS, cell based therapies and gene ...demerits. Neurotrophic factors are one particularly promising therapeutic and potentially neuroprotective ...
20
The roles of microRNAs in regulation of mammalian spermatogenesis
... niche factor glial cell line-derived neurotropic factor (GDNF) is the first well- defined paracrine factor that promotes SSC self-renewal ...
8
Heterozygous p.S811F RET gene mutation associated with renal agenesis, oligomeganephronia and total colonic aganglionosis: a case report
... Oligomeganephronia (OMN) is a type of hypoplastic kidney that most often represents congenital non-familial renal dysplasia [1]. Histopathologically, the number of nephrons per unit area is reduced, while those nephrons ...
5