Glioblastoma Multiforme
The complement system in glioblastoma multiforme
... GBM: Glioblastoma Multiforme; gC1qR: Globular C1q Receptor; GSC: Glioma Stem-like Cell; HIF: Hypoxia Inducible Factor; HMEC: Human Mammary Epithelial Cells; hPSC: human induced Pluripotent Stem Cells; HVEC: ...
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The future role of personalized medicine in the treatment of glioblastoma multiforme
... Abstract: Glioblastoma multiforme (GBM) remains one of the most malignant primary central nervous system tumors. Personalized therapeutic approaches have not become standard of care for GBM, but science is ...
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Passing across the blood-brain barrier in glioblastoma multiforme (GBM)
... therapeutic potential in chemotherapy is ultrasound-mediated drug delivery (USMD). In USMD, microbubbles with a diameter of 1-10 microns are used to mechanically break cell junctions and ultrasound waves, which are aimed ...
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Lycorine inhibits glioblastoma multiforme growth through EGFR suppression
... Background: Lycorine has been revealed to inhibit the development of many kinds of malignant tumors, including glioblastoma multiforme (GBM). Although compelling evidences demonstrated Lycorine ’ s ...
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Reprogramming glioblastoma multiforme cells into neurons by protein kinase inhibitors
... Glioblastoma multiforme (GBM) is the most common and most aggressive malignant primary brain tumor in humans. Despite multimodal therapy [surgery with ioniz- ing radiation and chemotherapy (temozolomide, ...
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The Impact of Surgery on the Efficacy of Adjuvant Therapy in Glioblastoma Multiforme
... Glioblastoma multiforme (GBM) is a brain tu- mor with an especially adverse prognosis. Despite the use of modern methods of surgical treatment supplemented with radical postsurgical radiothera- py combined ...
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Image-driven modeling of the proliferation and necrosis of glioblastoma multiforme
... Glioblastoma multiforme (GBM), the most common primary brain neoplasm in adults, represents the most malignant end of the glioma spectrum. Though the prognosis is generally poor, there is considerable ...
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Expression of MECOM is associated with unfavorable prognosis in glioblastoma multiforme
... Figure 1 (A) Representative immunohistochemistry figure of low-MECOM expression (left) and high-MECOM expression (right). Slides were observed under ×400 magnification and scale bar represents 50 μm. (B) The mrna of ...
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p53 and EGFR Expression in Glioblastoma Multiforme: An Immunohistochemical study
... As mentioned above although not statistically significant it was found in this study that patients with both p53 and EGFR over expression survived for a shorter period of time as compared to those with both genetic ...
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Congenital Glioblastoma multiforme and eruptive disseminated Spitz nevi
... Congenital glioblastoma: a clinicopathologic and genetic ...Congenital glioblastoma multiforme: a report of three cases and a review of the ...
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Genome-wide associations of signaling pathways in glioblastoma multiforme
... Gliomas represent a heterogeneous family of primary brain tumors that are a significant cause of cancer mortality in the United States [1] with glioblastoma multiforme (GBM) as their most aggressive form. ...
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High metallothionein predicts poor survival in glioblastoma multiforme
... Glioblastoma multiforme (GBM) is the most common and aggressive malignant brain tumor [1]. Survival rates vary between studies (20.0 to 61.1 % at 1 year) and only 2 %–5 % of patients are expected to survive ...
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Glioblastoma Multiforme Classification by Deep Learning Techniques on Histopathology Images
... Brain tumor turns into cancerous tumor (malignant) or to be found normal tumor (benign) based on its characteristics. Glial (malignant) tumor has these following stages Astrocytomas, Ependymomas, GBM (Glioblastoma ...
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Nanoparticles of carbon allotropes inhibit glioblastoma multiforme angiogenesis in ovo
... vessels. Glioblastoma multiforme cells were cultured on the chorioallantoic membrane of chicken embryo and after 7 days of incubation, were treated with carbon nanoparticles administered in ovo to the ...
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Comprehensive portrait of recurrent glioblastoma multiforme in molecular and clinical characteristics
... 14. Reardon DA, Egorin MJ, Quinn JA, Rich JN, Gururangan S, Vredenburgh JJ, Desjardins A, Sathornsumetee S, Provenzale JM, Herndon JE 2nd, Dowell JM, Badruddoja MA, McLendon RE, et al. Phase II study of imatinib mesylate ...
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Histologic findings associated with laser interstitial thermotherapy for glioblastoma multiforme
... 4 Histologic analysis of laser-induced thermal therapy treated left temporal glioblastoma multiforme revealed showed some hallmark characteristics including a mitotic body ( a ) a multin[r] ...
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Glioblastoma multiforme in Klippel Trenaunay Weber syndrome: a case report
... Introduction: Klippel-Trenaunay-Weber syndrome (KTWS) is a rare syndrome in which patients usually present with cutaneous hemangiomas, venous varicosities, and bone and soft tissue hypertrophy of the affected limb. ...
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Role of dimethyl fumarate in the treatment of glioblastoma multiforme: A review article
... 6. Ahmadi-Beni R, Khoshnevisan A. An overview of crucial genes involved in stemness of glioblastoma multiforme. Neurochemical Journal 2017; 11(4): 259-65. 7. Safari M, Khoshnevisan A. Cancer Stem Cells and ...
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New treatment options in the management of glioblastoma multiforme: a focus on bevacizumab
... Abstract: Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor in adults and carries the poorest prognosis. Despite recent progress in molecular biology, neuro-imaging and ...
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Glioblastoma Multiforme Causing Calvarial Destruction: An Unusual Manifestation Revisited
... 10. Rainov NG, Holzhausen HJ, Meyer H, Burkert W. Local invasivity of glioblastoma multiforme with destruction of skull bone: case report and review of the literature. Neurosurg Rev 1996;19:183–188 11. ...
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