glycopeptide antibiotic
New chiral stationary phase with macrocyclic glycopeptide antibiotic eremomycin chemically bonded to silica
... macrocyclic glycopeptide antibiotic eremomycin to the epoxy-activated silica under mild ...macrocyclic glycopeptide antibiotics affects remarkably the resulting ...
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Antimicrobial resistance (AMR) nanomachines: mechanisms for fluoroquinolone and glycopeptide recognition, efflux and/or deactivation
... the glycopeptide antibiotic teicoplanin occurs via efflux regulated by the TcaR regulator in ...and glycopeptide resistances, respectively, and the complexities of bacterial sensing mechanisms that ...
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Profile of oritavancin and its potential in the treatment of acute bacterial skin structure infections
... the glycopeptide antibiotic chloroeremomy- cin, received the US Food and Drug Administration approval for the treatment of acute bacterial skin and skin structure infections caused by susceptible ...
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Central venous catheter related infections: Risk factors and the effect of glycopeptide antibiotics
... using glycopeptide antibiotic during catheteriza- tion in comparison to patients who were not using these antibiotics (p = ...[12,20]. Glycopeptide antibiotics are active against Staphylococci, ...
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Eremomycin pyrrolidide: a novel semisynthetic glycopeptide with improved chemotherapeutic properties
... semisynthetic glycopeptide antibiotic eremomycin pyrrolidide (5) which may be a prospective antimicrobial agent for further pre-clinical and clinical ...
11
DETECTION OF VANCOMYCIN-RESISTANT ENTEROCOCCUS SPP. (VRE) FROM POULTRY
... many antibiotic therapies has become an important public health concern ...the glycopeptide antibiotic agent, vancomycin was useful in the treatment of severe infections due to gram-positive bacteria ...
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Update on the Antimicrobial Management of Foot Infections in Patients With Diabetes
... Treatment options for moderate to severe DFIs with MRSA include vancomycin, daptomycin, and line- zolid. Vancomycin, a glycopeptide antimicrobial, has been the tradi- tional agent used to cover MRSA in more severe ...
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Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns
... LD-block. Hereby, SNPs could be assigned to more than one LD-block. We then merged LD-blocks that were overlapping position-wise (see Figures S5A–F in Supplementary Material). This step takes care of SNPs for which no LD ...
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Detection of Enterococcal Surface Protein Gene (esp) and Amplified Fragment Length Polymorphism Typing of Glycopeptide Resistant Enterococcus faecium during Its Emergence in a Greek Intensive Care Unit
... of glycopeptide-resistant strains, we studied the characteristics of this outbreak, focusing on molecular typing with amplified fragment length polymor- phism (AFLP) analysis and esp gene ...
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A Transposon Screen Identifies Genetic Determinants of Vibrio cholerae Resistance to High-Molecular-Weight Antibiotics
... Gram-negative bacteria are notoriously resistant to a variety of high-molecular-weight antibiotics due to the limited permeabil- ity of their outer membrane (OM). The basis of OM barrier function and the genetic factors ...
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Once Daily Gentamicin Administration for Community Associated Methicillin Resistant Staphylococcus aureus in an in vitro Pharmacodynamic Model: Preliminary Reports for the Advantages for Optimizing Pharmacodynamic Index
... an antibiotic con- centration of four and eight times of the MIC for each organism and were incubated for 48 hours at 37˚C in order to monitor the development of ...
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Oligosaccharide moieties of the glycoprotein of vesicular stomatitis virus.
... The major products peak I produced by glycosidase digestion of the VSV glycopeptides from virus grown in HeLa cells consisted of a small glycopeptide fragment that contained glucosamine,[r] ...
9
Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance
... between antibiotic-treated and untreated animals at a significance level (alpha) of ...effective antibiotic treatment rapidly clear the infection and remain perfectly ...to antibiotic therapies ...
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Glycopeptide storage in skin fibroblasts cultured from a patient with alpha mannosidase deficiency
... The glycopeptide nature of the storage material isolated from cultured skin fibroblasts may be attributed to the low level of N-aspartyl-beta-glucosamindase (EC ...
9
Amyloid-like aggregation of provasopressin in diabetes insipidus and secretory granule sorting
... The large variety of more than 70 different known ADNDI mutations throughout the sequence of vaso- pressin and NPII strongly suggests that the common mechanism to cause disease is to prevent native fold- ing of the ...
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An investigation into the structure and function of VanS proteins involved in the two component VanS/VanR regulatory system controlling antibiotic resistance
... A recent comprehensive HTS program of chemical libraries by GSK in 2007, examining 500,000 small molecules against a range of antibacterial targets did not find any new drugs worthy of development (Payne et al., 2007). ...
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Use of antibiotics and asthma medication for acute lower respiratory tract infections in people with and without asthma: retrospective cohort study
... of antibiotic prescribing, although when analysis was restricted to the first ALRTI episode, this association was attenuated in patients with asthma and reversed in those ...an antibiotic for subsequent ...
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PATTERN OF ANTIBIOTIC USE AND THEIR RESISTANCE IN PATIENTS ADMITTED IN ICU
... Some strategies followed in ICUs for rational use of antimicrobial agents like de-escalation, monitoring serum levels of the drugs, appropriate duration of therapy and use of biological markers. This strategy requires ...
6
Glycopeptides of Murine Leukemia Viruses I. Comparison of Two Ecotropic Viruses
... 31, 1979 MuLV GLYCOPEPTIDES DISCUSSION The present results indicate that at least four different glycopeptide size classes are associated with glycoproteins of R-MuLV grown in JLS-V9 cel[r] ...
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Genomic analysis of an emerging multiresistant Staphylococcus aureusstrain rapidly spreading in cystic fibrosis patients revealed the presence of an antibiotic inducible bacteriophage
... with 9.2% being MRSA. This percentage increased in 2004, with a mean of 14.5%, with similar results in chil- dren and adults (unpublished data). Overall in our two centres in Marseille, prevalence of S. aureus was 61% ...
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