GPI-ANCHORED PROTEINS
Biogenesis of GPI anchored proteins is essential for surface expression of sodium channels in zebrafish Rohon Beard neurons to respond to mechanosensory stimulation
... of GPI (glycosylphosphatidylinositol) transamidase, which is essential for membrane anchoring of GPI-anchored ...of GPI-anchored proteins is necessary for cell surface expression ...
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Mutational Analysis of the Glycosylphosphatidylinositol (GPI) Anchor Pathway Demonstrates that GPI-Anchored Proteins Are Required for Cell Wall Biogenesis and Normal Hyphal Growth in Neurospora crassa
... of GPI anchoring in the synthesis of the ...the GPI anchor mutant colonies, where we find no evidence indicating that either the inner or outer cell is degen- ...
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Convergent extension movements in growth plate chondrocytes require gpi anchored cell surface proteins
... of gpi-anchored proteins, the spindle orienting mechanism is functional, but imprecise, resulting in a percentage of chondrocytes that divide out of ...Although gpi-anchored glypicans ...
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Glycosyl Phosphatidylinositol-Anchored Proteins in Chemosensory Signaling: Antisense Manipulation of Paramecium tetraurelia PIG-A Gene Expression
... a GPI-anchored protein involved in swimming behavior, such as a component of the voltage-gated calcium channel which functions in the calcium-based swimming turn, we would expect that attraction to ammonium ...
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De Novo Sphingolipid Synthesis Is Essential for Viability, but Not for Transport of Glycosylphosphatidylinositol-Anchored Proteins, in African Trypanosomes
... Sphingolipid synthesis and intracellular transport in mam- malian cells. In contrast to the situation for yeast (50, 59, 65), ER exit and intracellular transport of GPI-anchored proteins in ...
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COMPARATIVE GENOMICS USING CANDIDA ALBICANS DNA MICROARRAYS REVEALS ABSENCE AND DIVERGENCE OF VIRULENCE ASSOCIATED GENES IN CANDIDA DUBLINIENSIS
... Candida dubliniensis is a pathogenic yeast species closely related to Candida albicans. However, it is less frequently associated with human disease and displays reduced virulence in animal models of infection. We have ...
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Lipid rafts: linking prion protein to zinc transport and amyloid-β toxicity in Alzheimer's disease
... The GPI-anchored PrP C is localized in cholesterol-rich, detergent-resistant lipid rafts at the cell surface (Taylor et ...caveolin proteins, may lead to the local assembly of membrane protein ...
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Immunological characterization of Plasmodium vivax Pv32, a novel predicted GPI anchored merozoite surface protein
... (GPI)‑anchored proteins of Plasmodium parasites are exposed to neutralizing antibodies, and several are advanced vaccine ...predicted GPI‑ anchored and cysteine‑rich motif was ...
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Human LYPD8 protein inhibits motility of flagellated bacteria
... for recombinant hLYPD8 protein was observed at about the 75-kDa position (Fig. 1b). In addition, the treatment with peptide-N-glycosidase F (PNGase F), which cleaves N-oligosaccharide chains from glycoproteins, substan- ...
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GPI anchored complement regulatory proteins in seminal plasma An analysis of their physical condition and the mechanisms of their binding to exogenous cells
... three GPI- anchored proteins remained in the supernatant ...some GPI-anchored proteins in SP are not pros- tasome ...of proteins in this fraction to pellet during ...
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Insight into the Antiadhesive Effect of Yeast Wall Protein 1 of Candida albicans
... 33). GPI-anchored Sap9 may have a role in this shedding (52; our unpublished ...of GPI- anchored proteins may also result from cell wall remodeling or from washout during the ...
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Fate of Glycosylphosphatidylinositol (GPI)-Less Procyclin and Characterization of Sialylated Non-GPI-Anchored Surface Coat Molecules of Procyclic-Form Trypanosoma brucei
... a GPI anchor addition, the procyclins appear to be normally N-glycosylated in the ER, transported to the lysosomal com- partment, proteolytically degraded in the N-terminal do- main, and secreted from the cells ...
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GLYCOPHOSPHATIDYLINOSITOL ANCHORED PROTEINS IN PARAMECIUM TETRAURELIA
... many GPI-anchored proteins. If there are other proteins present in the salt/ethanol wash of whole cells, and hence available as antigens for the antisera, they are likely to be peripheral ...
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The Role of GPI-anchored PrPC in Mediating the Neurotoxic Effect of Scrapie Prions in Neurons
... of GPI anchors is poorly understood, and GPI anchored proteins may serve a variety of functions (receptors, adhesion, enzymes, complement regulation, signal ...of GPI anchors, along ...
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Signaling by epithelial members of the CEACAM family – mucosal docking sites for pathogenic bacteria
... are GPI-anchored proteins or that they sustain functionality in the absence of a cytoplasmic domain, the mechanistic details of signal transduction processes initiated by these CEACAM family members ...
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The role of Gpi-anchored axonal glycoproteins in neural development and neurological disorders.
... Precursor Proteins (APP, APLP1, APLP2; Ma et ...Contactin-associated proteins (CNTNAP/Caspr1-5; Gollan et ...the GPI-anchored proteins can interact with the ...
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Comprehensive Analysis of Glycosylphosphatidylinositol-Anchored Proteins in Candida albicans
... GPI-anchored proteins in C. albicans represent an extraor- dinary group of proteins localized to the cell ...involving proteins and ...of proteins would not have been possible ...
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Oral Delivery of Protein Drugs: Driver for Personalized Medicine?
... the GPI anchor and produced by recombinant technologies was used as model ...This GPI-anchored insulin was labelled with immunogold to enable visualization by electron ...the GPI- ...
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Release of exosomes and microvesicles harbouring specific RNAs and glycosylphosphatidylinositol anchored proteins from rat and human adipocytes is controlled by histone methylation
... the GPI-anchored protein CD73 and FSP27-specific mRNA (Müller, ...specific GPI-anchored proteins and RNAs from rat and human adipocytes is apparently not controlled by histone ...
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GPAA1 promotes gastric cancer progression via upregulation of GPI-anchored protein and enhancement of ERBB signalling pathway
... of GPI-APs from the cell surface via the cleavage site at the mannose-mannose linkage ...incising GPI-anchored proteins at the plasma membrane ...of GPI anchors in the human body. ...
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