Growth and Remodeling
Signaling effectors underlying pathologic growth and remodeling of the heart
... hypertrophic growth by enlarging individual myocytes to augment cardiac pump function and decrease ventricular wall ...hypertrophic growth is often compen- satory, but as time progresses these changes ...
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Optimization of bone growth and remodeling in response to loading in tapered mammalian limbs
... trading-off growth versus ...periosteal growth rate in response to loading is lower for the metatarsal than the tibia, causing the metatarsal to have a thinner cortex and lower section moduli to resist ...
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Post crisis Remodeling of the Economy for the Sustainable Growth of South Eastern European Countries
... economic growth model of selected South Eastern European economies (Albania, Bosnia, Macedonia, Serbia, Slovenia, Croatia, Bulgaria and Montenegro) during pre-global economic crisis was based mainly on foreign ...
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Dynamic Monitoring of Cellular Remodeling Induced by the Transforming Growth Factor-β1
... The phenomenon of plasticity of differentiated adult cells could have a great therapeutic potential, but at the same time, it is characteristic of progression of serious pathological states. Epithelial – mesenchymal ...
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Effects of resveratrol supplementation on bone growth in young rats and microarchitecture and remodeling in ageing rats
... and remodeling is less ...bone growth and bone mass accumulation during rapid growth in early life and modulate bone metabolism during early ageing, both of which are likely to be important for ...
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Rhinovirus-induced basic fibroblast growth factor release mediates airway remodeling features
... In addition to that, RV infection results in stimulation of MMP activity released by bronchial epithelial cells, in accordance to recent findings [38]. Increased MMP-9 levels have been detected in BAL fluid [39], ...
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Growth differentiation factor 15 contributes to marrow adipocyte remodeling in response to the growth of leukemic cells
... and growth of prostate cancers or ovarian cancers [4, ...phological remodeling of the mature adipocytes, includ- ing the reduction of adipocyte size and acquisition of fibroblast-like morphology ...
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Role of multidomain structure of urokinase in regulation of growth and remodeling of vessels
... плазмин. плазмин, в свою очередь, является активатором урокиназы и переводит одноце- почечную урокиназу в двухцепочечную фор- му. Двухцепочечная урокиназа обладает про- теазной активностью как по отношению к ...
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Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor β signaling
... Because NE proteins are implicated in cell proliferation and apoptosis (Cohen et al., 2001; Gruenbaum et al., 2005), we examined these processes in Man1 ⌬/⌬ embryos. We first analyzed cell proliferation in Man1 ⌬/⌬ ...
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Transforming growth factor beta 1 is decreased in remodeling hypertensive bovine pulmonary arteries
... The development of pulmonary hypertension in hypoxic newborn calves is associated with a complex pattern of increased tropoelastin and type I procollagen synthesis and deposition by smooth muscle cells in large elastic ...
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Growth factors and the regulation of bone remodeling
... Abbreviations used in this paper: aFGF, acidic FGF; 12 m, beta2 microglobulin; BDGF, bone-derived growth factor; bFGF, basic FGF; ECGF, endothelial cell growth factor; FGF, fibroblast gr[r] ...
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Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation
... postnatal growth and remodeling of the lung, we hypothesize that the observed hemorrhaging resulting from SMC-specific Nrp1 knockout may be due to defective alveolarization consequent upon im- paired ...
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Molecular Mechanisms of Pulmonary Arterial Remodeling
... A novel transcription factor, Oct-4 is also referenced as POU51, OCT-3/4 and OTF3/4 in the literature. Originally shown to be a critical mediator in main- taining human embryonic stem cells in an undifferentiated state, ...
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Bidirectional remodeling of β1-integrin adhesions during chemotropic regulation of nerve growth
... negative remodeling by MAG. In growth cones exposed to MAG (1 μ g/mL), surface immunostaining and quantitative analysis after image thresholding revealed a complete loss of clustered b1-integrin compared to ...
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Cardiac remodeling in postischemic end stage human hearts: Involvement of extracellular matrix and angiogenesis related molecules
... Tenascins (TNs) constitute another family of cardiac ECM proteins. We have investigated the roles of tenascin cytotactin (TN-C) and TN-X in modulating cell migra- tion and adhesion during angiogenesis. TN-C is strongly ...
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Dynamic Remodeling of Microbial Biofilms by Functionally Distinct Exopolysaccharides
... during growth (4, 38), and the variation between Psl expression and Pel expression may represent an im- portant adaptation strategy of ...centralize growth to the newly attached site when the biofilm has ...
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Original Article External stents inhibit intimal hyperplasia of rabbit autologous vein grafts via modulation of matrix metalloproteinase-2 expression
... nisms of inhibitory effects [13]. It has also been proposed as one of the mechanisms for the protective effects of ES, with adventitial angio- genesis and the promotion of vasa vasorum around the vein grafts [13, 14, ...
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Dynamic Remodeling of the Magnetosome Membrane Is Triggered by the Initiation of Biomineralization
... membrane remodeling mechanisms exist to achieve the distinct sizes and morphologies of organelles ...membrane remodeling, similar to the endoplasmic reticulum and mito- chondria (49, ...membrane ...
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Pericyte-targeting drug delivery and tissue engineering
... platelet-derived growth factor receptor β (PDGFR- β ), PDGFR- α , α -smooth muscle actin ( α SMA), and smooth muscle myosin heavy ...lar remodeling during neovascularization, as reported by Berger et ...
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Chronic allograft rejection: A significant hurdle to transplant success
... and growth factors (PDGF, transforming growth factor (TGF)-β, endothelial growth factor (EGF), vascular endothelial growth factor (VEGF), and chitinase and chitinase-like proteins involved in ...
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