H/sub 3/PO/sub 4/
Fe<sub>3</sub>O<sub>4</sub>-based PLGA nanoparticles as MR contrast agents for the detection of thrombosis
... Fe 3 O 4 -based poly(lactic-co- glycolic acid) (PLGA) nanoparticles (NPs) surface-modified with a cyclic Arg-Gly-Asp (cRGD) peptide as an MR contrast agent for the detection of ...Fe 3 O 4 ...
14
NH<sub>4</sub>HCO<sub>3</sub> gas-generating liposomal nanoparticle for photoacoustic imaging in breast cancer
... of 3:1:1, cholesterol-free distearoylphosphatidylcho- line, distearoylphosphatidylethanolamine–polyethylene glycol 2000 (Avanti Polar Lipids, ...min. 3) After the rota- tion, 5 mL of NH 4 HCO ...
11
Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>/DNR magnetic nanoparticles in the treatment of hematologic malignancies
... Blood was obtained from healthy rabbits and anticoagulated with potassium oxalate, at a final concentration of 1.0 mg/mL of blood. The Fe 3 O 4 -MNPs/DNR were scrubbed with distilled water twice, lixiviated ...
6
Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... Samples of tumor tissue weighing 0.1 g was collected from each mouse and homogenized for detection of P- glycoprotein, Bcl-2, Bax, and caspase-3. Briefly, the tissues were extracted with Triton X-100, and the ...
9
Fe<sub>3</sub>O<sub>4</sub>/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
... HAuCl 4 solution containing ...in 3% bovine serum albumin and phosphate-buffered solution at 37 ° C for one hour to block excess active groups and nonspecific binding sites on the ...
11
Pharmacokinetic parameters and tissue distribution of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles in mice
... Fe 3 O 4 MNPs in the various organs and tissues is shown in Figures 3 and ...Fe 3 O 4 MNPs at all time points between the experimental and control groups, there were statistically ...
6
The effects of magnetite (Fe<sub>3</sub>O<sub>4</sub>) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH<sub>3</sub>) cells and in RAW 264.7 macrophages
... Figure 4, when cells were exposed to Fe 3 O 4 NPs (100 µ g/mL), there was a progressive decrease in the activity of MEP-induced channels, which occurred at the level of hyperpolarizing potentials ...
10
Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... minor modifications. An aqueous solution of doxorubicin 5 mg/5 mL was emulsified in 10 mL dichloromethane, in which 120 mg of the copolymer and 4 mg magnetic nanopar- ticles had been dissolved, using a probe ...
16
Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>@Au composite magnetic nanoparticles in vitro and in vivo
... OH 3 HCl and HAuCl 4 ) were performed during the reaction, and the stirring continued for at least 30 minutes after each ...Fe 3 O 4 @Au composite ...
15
The effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> on immune function in normal ICR mice
... Nanotechnology offers an efficient alternative for cancer diagnostics and tumor target treatment due to the unique properties of nanostructures, such as large surface-to-volume ratio, porous structure, embedded effect, ...
7
Immobilized transferrin Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery
... Fe 3 O 4 @SiO 2 -based drug delivery system that combines three properties: magnetic targeting, TfR targeting, and high DOX ...Fe 3 O 4 @ SiO 2 nanoparticle (DMP) was synthesized as a ...Fe ...
9
Biocompatibility of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their cytotoxic effect on MCF-7 cells
... Fe 3 O 4 nanoparticles were approximately spherical, with diameters of about ...Fe 3 O 4 was determined by scanning electron microscopy-energy dispersive x-ray spectroscopy elemental analysis, ...
10
The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... Fe 3 O 4 magnetic nanoparticles (Fe 3 O 4 ...Fe 3 O 4 -MNPs were synthesized, and their characteristics such as particle size, zeta potential, and X-ray diffraction patterns were ...
6
Effect of interaction of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and artesunate on apoptosis of K562 cells
... purchased: 3-(4, 5- dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) (Ameresco, Solon, OH); Z-VAD-FMK (Beyotime Biotechnology); RPMI 1640 medium and fetal calf serum (GIBCO, USA); artesunate ...
8
Synergistic effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> with gambogic acid on apoptosis of K562 leukemia cells
... MNPs-Fe 3 O 4 induced apoptosis not only through influencing the regulatory factors in the intrinsic mitochondrial pathway such as bax and bcl-2, but also through regulating the transcription factor NF- κ B ...
9
Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... (Fe 3 O 4 ) nanoparticles and incorporate them into ...Fe 3 O 4 were first synthesized by chemical co-precipitation and then coated with dextran ...Dex/Fe 3 O 4 particles were ...
12
Synergistic effect of a combination of nanoparticulate Fe<sub>3</sub>O<sub>4</sub> and gambogic acid on phosphatidylinositol 3-kinase/Akt/Bad pathway of LOVO cells
... pro-caspase 3, and caspase ...pro-caspase 3, caspase 3, or β -actin antibody, and then sub- sequently incubated with horseradish peroxidase-conjugated goat antirabbit (1:5000) as a secondary ...
10
Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... sulfate [SDS], 20% glycerol) containing the protease inhibitor phenylmethanesulfonyl fluoride 0.1 mM/L. We separated 50 µ g of proteins on SDS–polyacrylamide gel electrophoresis 10%. Proteins were transferred to ...
8
Vancomycin-modified Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@Ag microflowers as effective antimicrobial agents
... Van/Fe 3 O 4 @SiO 2 @Ag microflower with enhanced antibacterial activity is experimentally and theoretically presented in this ...Van/Fe 3 O 4 @SiO 2 @Ag microflowers can rapidly and ...
18
Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... strategy is to treat tumor cells with antioxidants, such as through the dietary administration of red wine and green tea polyphenols to prevent cancer. The other strategy is to provide pro-oxidant therapy, which consists ...
10