helper 1
T Helper 1/T Helper 2 Cytokine Imbalance in Respiratory Syncytial Virus Infection Is Associated With Increased Endogenous Plasma Cortisol
... T helper 1 (Th1) and Th2, on the basis of the cytokine profiles they ...Type 1 T cells produce interferon ␥ (IFN- ␥ ), an essential cytokine in the viral cell-mediated immune ...
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Interleukin-22 Promotes T Helper 1 (Th1)/Th17 Immunity in Chlamydial Lung Infection
... The role of interleukin-22 (IL-22) in intracellular bacterial infections is a controversial issue, although the contribution of this cy- tokine to host defense against extracellular bacterial pathogens has been well ...
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Adenovirus Serotype 5 Vaccination Results in Suboptimal CD4 T Helper 1 Responses in Mice
... CD4 T cells orchestrate immune responses against various types of pathogens by differentiating to diverse effector subsets with unique effector functions (10, 11). During viral infection, for example, lymphocytic ...
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Imbalanced shift of cytokine expression between T helper 1 and T helper 2 (Th1/Th2) in intestinal mucosa of patients with post-infectious irritable bowel syndrome
... T helper 1 and T helper 2 (Th1/Th2) in intestinal mucosa of PI-IBS patients, suggesting that an immune dysregula- tion mechanism was involved in the ...
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Cell fate decision: T helper 1 and 2 subsets in immune responses
... kinase 1 for instance, I-κB kinases are activated and phos- phorylate I- κ B proteins, which leads to their dissociation from NF-κB and degradation by ubiquination-dependent proteosomes, and NF-κB proteins ...
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Enhanced IgG4 production by follicular helper 2 T cells and the involvement of follicular helper 1 T cells in the pathogenesis of IgG4 related disease
... follicular helper T (Tfh) cells and B cells at the germi- nal center plays a major role in antibody production, immunoglobulin-isotype switching, affinity maturation, and plasmablast and plasma-cell genesis [16, ...
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Natural killer cells control a T helper 1 response in patients with Behçet's disease
... How the NK2 cells from iBD patients suppress the IFNγ expression in Th1 cells, however, remains unclear. One potential soluble mediator in our cell-contact-free culture system is IL-13, a typical T-helper 2 ...
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T-helper 1 versus T-helper 2 lymphocyte immunodysregulation is the central factor in genesis of Burkitt lymphoma: hypothesis
... The hypothesis is consistent with the concept that onco- genic cellular lesions that result in cancers may be a con- sequence of an adaptive response to biologic stresses [38]. It highlights the polyclonal ...
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Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN gamma secreting TH1 cells in humans
... T helper 2 (TH2)-type cells in the anti- CD4 treated group was observed, numbers of IFN-gamma-producing T helper 1 (TH1)-type cells remained stable, resulting in a significant increase in the TH1/TH2 ...
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Local Expression of T Cell Subsets in Sensitized and Unsensitized Experimental Cystic Echinococcosis.
... Signal transducer and activator of transcription (STATs) are DNA-binding transcription factors that induce the transcription of their target genes by recognizing specific DNA consensus sequences. STATs family proteins ...
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Two-Helper RNA System for Production of Recombinant Semliki Forest Virus Particles
... mutated helper, cells were coelectroporated with SFV-lacZ, SFV-helper-S1, and SFV-helper-C-S219A ...Table 1), indicating that the mutation in the capsid did not affect the functionality of the ...
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Immune function after major surgical interventions: the effect of postoperative pain treatment
... Notes: Blood samples were obtained before surgery, immediately after the end of surgery and 24 and 48 hours later. PBMC were stimulated in vitro for 24 hours with 10 µg/ mL PHA, and INF-γ (A), IL-2 (B), IL-4 (C) and ...
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Immune contexture defined by single cell technology for prognosis prediction and immunotherapy guidance in cancer
... application of immunotherapy have brought hope to countless patients by improving their PFS and OS rate. Tumor cells can suppress the immune system by activat- ing immune checkpoints to achieve immune escape [43]. Among ...
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Alveolar T helper 17 responses to streptococcus pneumoniae are preserved in ART untreated and treated HIV infected Malawian adults
... HIV-1-infected participants were divided into two sub- groups based on whether they were on ART or not at the time of recruitment. First line ART consisted of stavudine, lamivudine, and nevirapine, or tenofovir, ...
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Assisted-Leach (A-Leach) Energy Efficient Routing Protocol for Wireless Sensor Networks
... in Helper nodes selection and route set up ...among helper and cluster head nodes. We propose algorithms for helper node selection and multi-hop ...
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Proportions of circulating follicular helper T cells are reduced and correlate with memory B cells in HIV infected children
... follicular helper cells are expected to be antigen- experienced, the proportions of memory follicular-homing CD4 T cells were also determined based on the additional expression of CD45RO, the marker of memory in T ...
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Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report
... Our patient was diagnosed as having MM IgG-κ chain type, stage IIIA according to the Durie-Salmon system and stage II according to the International Sta- ging System. Following a definite diagnosis, she re- ceived a VRD ...
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The antiretrovirus drug 3'-azido-3'-deoxythymidine increases the retrovirus mutation rate.
... It was previously observed that the nucleoside analog 5-azacytidine increased the spleen necrosis virus (SNV) mutation rate 13-fold in one cycle of retrovirus replication (V. K. Pathak and H. M. Temin, J. Virol. ...
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Selective induction of rheumatoid factors by superantigens and human helper T cells
... particular polymorphism of the V beta gene segment. Data presented here demonstrate that the staphylococcal enterotoxin D (SE D), but not other bacterial superantigens, exhibits an ability to induce IgM, IgG, and ...
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Performance evaluation of Cooperative MAC and ZRP in Cooperative Communication Networking Environment
... a helper. We ran different experiments changing the position of the helper between the different regions by forcing the data rates between the source, helper and destination ...the helper, ...
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