hematopoietic stem/progenitor cells
Open the gates: vascular neurocrine signaling mobilizes hematopoietic stem and progenitor cells
... of hematopoietic stem and progenitor cells (HSPCs) from the bone marrow (BM) into the peripheral blood is a complex process that is enhanced dramatically under stress-induced ...for ...
5
Enhanced self-renewal of hematopoietic stem/progenitor cells mediated by the stem cell gene Sall4
... NB4 cells as well as normal human CD34+ BM cells ([20], and unpub- lished ...transduction. Cells were collected and total RNAs were prepared and subjected to qRT-PCR ...LSK cells, there were ...
14
Active RHOA favors retention of human hematopoietic stem/progenitor cells in their niche
... To determine the effect of RHOA on the migration of HSPCs, RHOA transduced HSPCs were allowed to migrate in a transwell chamber towards SDF1α gradient. Post-migration analysis showed that there was a significant increase ...
8
Arterial endothelium creates a permissive niche for expansion of human cord blood hematopoietic stem and progenitor cells
... stromal cells and growth factors has been utilized in an attempt to ex vivo recapitulate in- teractions in hematopoietic microenvironment to expand ...CB stem cells in clinical ...
13
Engineering approaches for regeneration of T lymphopoiesis
... T cells, to deplete the endogenous T cells from FTOC while maintaining the surviving stromal ele- ments ...lymphoid cells of different haplotypes, and has become a great platform to study T cell ...
10
Functional similarities of microRNAs across different types of tissue stem cells in aging
... tissue stem cells (TSCs) contribute to loss of tissue homeostasis, including re- ductions in lymphopoiesis and the long-term repopu- lating abilities of hematopoietic stem/progenitor ...
5
Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells
... cell (CFC) (Figure 5E) and SLAM LSK cell (Figure 5F) mobiliza- tion response to G-CSF to the level seen in WT mice. Similarly, coadministration of NPY 3-36 and G-CSF reversed the attenuation of CFC mobilization ...
15
Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects
... CD34+ cells, which peaked at 60 minutes-post administration and subsided at 120 minutes ...marrow cells was assessed, in which a 60% enhancement of growth was reported ...marrow cells from mice ...
10
Vol 70, No 3 (2018)
... – hematopoietic stem cells; HSPC − hematopoietic stem/progenitor cells; HOXB4 – homeobox protein Hox-B4; TNC –total nucleated cells; CFU – colony forming unit; MSC ...
9
The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis
... epithelial cells in the ...leukemic cells of 90% of patients with acute myeloid leukemia (AML) but not in hematopoietic stem and progenitor cells derived from normal ...murine ...
13
Circulating hematopoietic stem cell count is a valuable predictor of prematurity complications in preterm newborns
... circulating progenitor cells in respiratory system disorder found in neonates born ...+ progenitor cells compared to ...+ cells were correlated with a prolonged duration of mechanical ...
16
Intrathymic injection of hematopoietic progenitor cells establishes functional T cell development in a mouse model of severe combined immunodeficiency
... affect hematopoietic stem cells in the bone marrow by impairing their ability to differentiate into ...marrow-derived hematopoietic progenitor cells, is atro- phied from lack of ...
9
A case of minor BCR-ABL1 positive acute lymphoblastic leukemia following essential thrombocythemia and originating from a clone distinct from that harboring the JAK2-V617F mutation
... in hematopoietic stem and progenitor cells (HSPCs), but not in the CD34 + CD19 + population that mostly consists of Ph + ALL cells, indicating that this Ph + ALL clone did not originate ...
5
Bone marrow characterization in COPD: a multi-level network analysis
... HSC: Hematopoietic stem cells; EPC: Endothelial progenitor cells; TNF R80: Tumour necrosis factor receptor p80; TGF-ß: Transforming growth factor beta; HGF: Hepatocyte growth factor; ...
9
Activated fibronectin-secretory phenotype of mesenchymal stromal cells in pre-fibrotic myeloproliferative neoplasms
... stromal cells (BMSC) from patients with pre-fibrotic myeloproliferative neoplasms ...normal hematopoietic stem and progenitor cells and displayed increased matrix remodelling (in ...
5
Regulation of human hematopoietic stem cell lineage commitment
... My thesis projects focus on identifying and characterizing regulatory factors involved in myeloid commitment steps for human hematopoietic stem and progenitor cells (HSPCs), so as [r] ...
143
Hematopoietic stem cells from peripheral blood the perspective of non mobilized peripheral blood
... vitro expansion. Results from pilot clinical trials of transplants using expanded UCB-HSC have shown no adverse effects in the patients. However, more clinical trials must be conducted using expanded HSC for guar- ...
9
PubMedCentral-PMC4974169.pdf
... of hematopoietic function and a number of clinical parameters, such as blood oxygen-carrying capacity, inflammation, and ...in hematopoietic cell lines and follow-up tar- geted knockdown experiments in ...
8
Expansion of Cord Blood Hematopoietic Stem Cells on the Amniotic Membrane Derived Mesenchymal Stem Cells
... Clinical trials have basically shown that UCB transplantation causes less graft versus host disease (GVHD) and graft failure (8). Recipients seem to be less sensitive to HLA mismatching when UCB is used as a source of ...
9
Cusan, Monica (2012): Studie über das leukämogene Potential der Hoxb4-DeltaProlin Mutante in einem murinen Knochenmarkstransplantationsmodell und den Effekt der Hemmung von Histondeacetylasen in vitro und in vivo. Dissertation, LMU München: Medizinische Fakultät
... of cells with LTC-IC (long-term culture-initiating cells) activity, to promote the development of B cells in vivo, and to increase the number of cells able to repopulate NOD/SCID mice (Buske ...
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