Hepatic lipid accumulation
Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man
... increased hepatic lipid accumula- tion ...increased hepatic lipid accumulation ...in hepatic steatosis is fueled by in- creased DNL, which may represent an important driver to ...
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Caffeine reduces hepatic lipid accumulation through regulation of lipogenesis and ER stress in zebrafish larvae
... reduce hepatic lipid accumulation in zebrafish, which was coordinated with the results of previous researchers studying the effects of caffeine in human [27, 29], rats [38] and hepatocytes ...reduced ...
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Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation through β-catenin accumulation
... mouse hepatic cells were obtained from the 10 weeks old WT or parkin KO mouse liver as described previously ...primary hepatic cells, the cells from the liver of WT or parkin KO mouse were treated with ...
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ORAL SUPPLEMENTATION WITH RUTIN, A FLAVONOL GLYCOSIDE, INHIBITS ETHANOL INDUCED HEPATIC LIPID ACCUMULATION IN EXPERIMENTAL RATS
... induced hepatic lipid accumulation in experimental ...glucose. Hepatic injury was induced in groups 3 and 4 by administering 20% ethanol via intragastric intubation for ...in lipid ...
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Schisandra polysaccharide inhibits hepatic lipid accumulation by downregulating expression of SREBPs in NAFLD mice
... dered lipid metabolism is considered a key ...late lipid metabolism in the liver, with the aim to dis- cover novel drug targets for the prevention and treatment of NAFLD are being carried ...
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Sake lees extract improves hepatic lipid accumulation in high fat diet-fed mice
... rated hepatic TG accumulation in the HFD ...and lipid content of the SL extract group were significantly lower than those in the HFD ...body lipid accumulation and serum components in ...
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Low-arginine and low-protein diets induce hepatic lipid accumulation through different mechanisms in growing rats
... stimulate lipid accumulation [9, ...the lipid accumulation level, serum lipid profile, glucose tolerance, and insulin signal activ- ...and lipid oxidation [26], we evaluated ...
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A gender related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator activated receptor alpha deficient mice
... the hepatic and cardiac dysfunction caused by inherited defects in b -oxidation has not been characterized; potential contributing factors include energy deficiency or ac- cumulation of toxic intracellular ...
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Direct comparison of metabolic health effects of the flavonoids quercetin, hesperetin, epicatechin, apigenin and anthocyanins in high-fat-diet-fed mice
... and hepatic lipid ...with lipid homeostasis, which could be possibly regulated via ...on hepatic Cyp2b9 expression and adiposity are mechanistically related, but this requires further investi- ...
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Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis
... We found that the homeostatic state of accelerated but healthy adi- pogenesis shifts towards adipocyte dysfunction and increased ectopic lipid accumulation when Cyp2j4 / rats are fed with CAF or left aging ...
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Crocin ameliorates hepatic steatosis through activation of AMPK signaling in db/db mice
... attenuated hepatic lipid accumulation and liver injury, as evidenced by decreased liver weight, serum levels of AST and ALT, liver TG level and morphological ...and lipid metabolic ...
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Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling
... resistance, and fatty liver disease. Here we have dissected mechanisms underlying this association using mice fed either chow or HFD with or without fructose- or glucose-supplemented water. In chow-fed mice, there was no ...
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High feeding intensity increases the severity of fatty liver in the American mink (Neovison vison) with potential ameliorating role for long-chain n-3 polyunsaturated fatty acids
... Fatty liver syndrome is a common metabolic disease in farmed American mink ( Neovison vison ) and it has been reported to develop during acute stressful periods, when mink may show a loss in appetite for a few days [1]. ...
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Selective Glucocorticoid Receptor Modulation Prevents and Reverses Nonalcoholic Fatty Liver Disease in Male Mice
... therapeutics.. 1 CORT118335 prevents and reverses hepatic lipid accumulation. A-C) C118 reduced body weight, fat mass and lean mass. H) C118 increased intravenous glucose tolerance in we[r] ...
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Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway
... in lipid me- tabolism, we first examined NAMPT expressions in the liver from normal diet (ND)- and high fat diet (HFD)- fed ...affects hepatic lipid accumulation, we examined the lipogenesis ...
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Silica nanoparticles trigger hepatic lipid-metabolism disorder in vivo and in vitro
... on hepatic lipid metabolism is ...disturb hepatic lipid metabolism in vivo and in ...and hepatic lipid levels through repeated intravenous administration, meanwhile, the protein ...
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Leucine Biosynthesis Is Involved in Regulating High Lipid Accumulation in Yarrowia lipolytica
... in lipid accumula- ...of lipid accumulation accompanied by downregu- lation of several amino acid biosynthetic pathways, including that of leucine in par- ticular, and these changes were further ...
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Dietary resveratrol increases the expression of hepatic 7α-hydroxylase and ameliorates hypercholesterolemia in high-fat fed C57BL/6J mice
... characterized the underlying mechanism of the effects of RSV in HepG2 hepatocytes by Western blot analysis. Results: RSV (200 mg/kg per day) reduced body weight and liver weight gains, improved serum lipid ...
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Growth kinetics and lipid accumulation in Rhodosporidium toruloides
... Studying the growth of R. toruloides on pure glycerol was very important because it gave a clear understanding on whether R. toruloides can as well grow on the impurities in crude glycerol since the only difference ...
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Hepatoprotective effect of licorice, the root of Glycyrrhiza uralensis Fischer, in alcohol induced fatty liver disease
... that both oxidative stress and inflammation as second hits are critical factors in the pathological progression from simple fat accumulation to liver disease. Recently, we re- ported that licorice extract had an ...
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