HepG2 Cells
on proliferation and apoptosis of human HepG2 cells
... the HepG2 cells, which may involve the PPARγ-nondependent ...the HepG2 cells by 15d-PGJ 2 , but in the cells transfected with PPARγ-pSG5 expression plasmid, 15d-PGJ 2 restored its above ...
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Lipid-Modulating Effects of Aqueous Extract of Rubus Occidentalis in Hepatocarcinoma HepG2 Cells
... Abstract: Little knowledge exists on the lipid-modulating effect of Rubus occidentalis (RO). The present study investigated the molecular mechanisms of lipid-modulating effects of aqueous extract of RO (ROW) in ...
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PKCα mediated induction of miR-101 in human hepatoma HepG2 cells
... PKC is a member of serine/threonine kinase whose iso- forms have been shown to be involved in a number of cel- lular processes, including cell proliferation, apoptosis, invasion and migration [9,10]. Various PKC isoforms ...
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Effects of statins on the secretion of human serum albumin in cultured HepG2 cells
... The structure of HMG-CoA reductase and complexes with six statins have been determined by X-ray crystallographic studies [23]. All statins function similarly by binding to the active site of HMG-CoA reductase and thus ...
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The utility of HepG2 cells to identify direct mitochondrial dysfunction in the absence of cell death
... mitochondrial toxicity when used alongside HepG2 cells in the presence of glucose. Furthermore, the dual assessment of ATP con- tent alongside cytotoxicity provides an enhanced mechanistic understanding of ...
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Involvement of mitochondrial pathway in NCTD-induced cytotoxicity in human hepG2 cells
... -treated HepG2 cells, cyto c was detected after a 24 h treatment ...NCTD-treated cells, the release of cyto c from the mitochondria was followed by activation of caspase-9 and ...
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Apigenin and hesperidin augment the toxic effect of doxorubicin against HepG2 cells
... on HepG2 cells, reducing the cells’ viability by approximately ...cancer cells even though the cell’ s oxygenation is normal [8, ...cancer cells [22–27] or makes the cancer cells ...
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Heat shock protein 70 promotes lipogenesis in HepG2 cells
... in HepG2 cells, we established HepG2 cells stably overexpressing human ...in HepG2 cells compared with cells stably expressing the empty lentiviral vector ...in ...
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Taurine reduces the secretion of apolipoprotein B100 and lipids in HepG2 cells
... hepatoblastoma cells, HepG 2, as a model of human liver. HepG2 cells have been found to retain many typical functions of the normal human hepatocytes, including lipoprotein and apolipoprotein ...
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Effects of quercetin on ionizing radiation-induced cellular responses in HepG2 cells
... in HepG2 cells. (A) HepG2 cells were exposed to querce n (100 μM) for 48 h with or without irradia on (10 Gy), and the protein expressions of p53, p21, Bax, Bcl-2, cleaved caspase -3, cleaved ...
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Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
... treated HEPG2 cells was approximately 4 fold higher that in controls (Figure 3A and ...Amitriptyline-treated HepG2 cells (Figure 3A and ...control cells versus 65±12.86 in cells ...
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Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation
... HepG2 cells were transfected with GFP-light chain 3 (LC3) in the pcDNA3 plasmid using Lipofectamine 2000 (Invitrogen, USA) in serum- and antibiotic-free medium for 6 hours, followed by a 72 hours incubation ...
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ABCC6 knockdown in HepG2 cells induces a senescent-like cell phenotype
... of HepG2 cells that lack ABCC6 ...knockdown HepG2 cells showed dysregulation of some genes related with the calcification processes, such as the tissue nonspecific alkaline phosphatase (TNAP), ...
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Multifunctional selenium nanoparticles as carriers of HSP70 siRNA to induce apoptosis of HepG2 cells
... normal cells. The cytotoxicity of Se@PEI@siRNA was lower for normal cells than tumor cells, indicating that these compounds may have fewer side ...cancer cells became more sensi- tive to ...
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Synergistic effect of phytochemicals on cholesterol metabolism and lipid accumulation in HepG2 cells
... of HepG2 cells resulted in a marked decrease in lipid deposition in comparison to individual CRO, CGA, GEN, and QUE treatment, determined by Oil red O staining, and trigly- ceride and total cholesterol ...
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In vitro infection of human hepatoma (HepG2) cells with hepatitis B virus.
... To further characterize the structures of extraceilular HBV proteins and to determine whether the virus was released from in vitro-infected HepG2 cells, viral particles pelleted from cul[r] ...
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The roles of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells
... tumor cells grow including those of colon, lung, skin, breast, liver origins and prostate ...HL-60 cells in a dosedepen- dent manner, DADS promoted caspase-3 activity and increased cyclin E and decreased ...
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Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells
... of HepG2 cells was assessed using MTT dye reduction assay (Sigma, USA), which was conducted as described previously ...[23]. Cells were seeded in a 96-well plate at a density of 1 ×10 4 ...
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Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53
... the cells were not apoptotic and did not exhibit DNA ...treatment, cells began to display apoptotic ...the HepG2 cells, indicat- ing the presence of DNA ...apoptotic cells, whereas at ...
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Azoles expressed cyto protective effects to hepg2 cells
... liver cells that showed it can cause angiogenesis as we observed in this ...study, HepG2 cells are used as liver cell ...more cells in liver vitro study was based on one group of cells ...
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