Herpes simplex virus type 1 infection
Nucleolin Is Required for an Efficient Herpes Simplex Virus Type 1 Infection
... The results of our experiments using cycloheximide and HSV-1 mutants demonstrate that the early delocalization of nucleolin from the nucleolus is not the consequence of the release of viral proteins from the ...
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Extracellular vesicles during Herpes Simplex Virus type 1 infection: an inquire
... HSV-1 infection vesicles are delivered from infected to uninfected cells that influence the infection; b) the cargo of these vesicles consists of viral and host transcripts (mRNAs, miRNAs and ...
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The fibroblast growth factor receptor is not required for herpes simplex virus type 1 infection.
... receptor fragment was able to bind bFGF directly and inhibited bFGF binding and receptor activation; however, the soluble receptor did not inhibit HSV-1 infection of either Vero cells or[r] ...
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Phosphorylation of Transcription Factor Sp1 during Herpes Simplex Virus Type 1 Infection
... HSV infection, the viral genes are ex- pressed such that those possessing binding sites for transcrip- tion factors, including Sp1, in their upstream promoter regions are expressed ...
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Clinical Manifestations of Primary Herpes Simplex Virus Type 1 Infection in a Closed Community
... The clinical features and the molecular ep- idemiology ofprimary herpes simplex virus type 1 (HSV- 1) infection among children younger than 3 years of age were investigated in day-cane n[r] ...
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The transneuronal spread phenotype of herpes simplex virus type 1 infection of the mouse hind footpad.
... Viral infection primarily involved the ascending sensory pathways of nociception and ...proprioception. Infection was detected in first-order neurons of the dorsal root ganglia and traced into the dorsal ...
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Soluble glycoprotein D blocks herpes simplex virus type 1 infection of rat eyes.
... Herpes simplex virus type 1 (HSV-1) ocular infection in rats was blocked by treating the eyes with UV-.. inactivated virions containing glycoprotein D (gD) prior to ocular challenge.[r] ...
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NF-κB Is Required for Apoptosis Prevention during Herpes Simplex Virus Type 1 Infection
... for 1 h or treated with PMA for 45 min, and the cells were fixed and permeabilized for immunofluorescence using anti-NF-B p65 antibody as described in Materials and ...
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Noninvasive Bioluminescence Imaging of Herpes Simplex Virus Type 1 Infection and Therapy in Living Mice
... Although we anticipate that bioluminescence imaging will enhance research into pathogenesis of HSV-1 in vivo, this imaging modality will not completely replace conventional as- says. Because the spatial resolution ...
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Interleukin-18 Protects Mice against Acute Herpes Simplex Virus Type 1 Infection
... HSV-1 infection between C57BL/6 and beige mice, one of whose immune deficiency characteristics is a lack of NK cell ...to infection with 10 4 PFU of HSV-1 than did BALB/c mice, but as known ...
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Neutrophil-mediated suppression of virus replication after herpes simplex virus type 1 infection of the murine cornea.
... CD8 1 T-cell population. Effect of MAb RB6-8C5 administration on HSV-1 replica- tion in the eyes of SCID ...CD8 1 T cells have been reported to participate in HSV-1 clearance from infected ...
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Impact of Rac1 and Cdc42 Signaling during Early Herpes Simplex Virus Type 1 Infection of Keratinocytes
... for herpes simplex virus type 1 (HSV-1) in ...HSV-1 infection of epithelial cells, and thus, we investigated the impact of Rac1 and Cdc42, which serve as key ...
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Modification and Reorganization of the Cytoprotective Cellular Chaperone Hsp27 during Herpes Simplex Virus Type 1 Infection
... with herpes simplex virus type 1 ...for virus induced chaperone enriched, contain Hsc70, Hsp70, Hsp40, Hsp90, polyubiquitinated proteins, and components of the proteasome ...
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PML Contributes to a Cellular Mechanism of Repression of Herpes Simplex Virus Type 1 Infection That Is Inactivated by ICP0
... the virus-infected ...wt virus infections they are transient and later disperse through the activities of HSV-1 ICP0 and HCMV IE1, the viral regulatory proteins that bring about the disruption of ...
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Nuclear Sequestration of Cellular Chaperone and Proteasomal Machinery during Herpes Simplex Virus Type 1 Infection
... It is clear that HSV-1 causes a dramatic nuclear redistribu- tion of the chaperone and proteasomal machinery during in- fection, but whether this is essential for portal assembly and efficient viral production ...
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Gender Influences Herpes Simplex Virus Type 1 Infection in Normal and Gamma Interferon-Mutant Mice
... (Tables 1 and 2), and use of IFN-␥ null mutant mice eliminates any potential effect of estrogen on the IFN-␥ ...abnormality; 1, eyelid hair loss; 2, periocular hair loss extending ⬍3 mm from the eyelid; 3, ...
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Linker Histones Are Mobilized during Infection with Herpes Simplex Virus Type 1
... with herpes simplex virus type 1 (HSV-1) genomes and localize to replication compart- ments early during ...HSV-1 infection modulates histone mobility, using ...
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Circularization of the Herpes Simplex Virus Type 1 Genome upon Lytic Infection
... A central feature of the above model is that HSV-1 genomes should be circularized prior to replication. Restriction enzyme analysis of infecting molecules indicates that terminal genomic fragments remain readily ...
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Detection of herpes simplex virus type 1 transcripts during latent infection in mice.
... Total cellular RNAs were isolated from the trigeminal ganglia of acutely (5 days postinfection) and latently infected mice, Northern blotted (5 ,g per lane), and hybridized to a nick-tra[r] ...
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Two outbreaks of herpes simplex virus type 1 nosocomial infection among newborns
... Further and more fine cleavage analysis of each genome with five REs showed that three isolates of the first or the second instance were essentially identical, indicating that they were [r] ...
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