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High grade gliomas

Differential expression of p42 3 in low  and high grade gliomas

Differential expression of p42 3 in low and high grade gliomas

... malignant gliomas include loss of heterozygosity 10 ( LOH10 ), phosphatase and tensin homolog ( PTEN ), tumor protein p53 ( TP53 ), epidermal growth factor receptor ( EGFR ) and P16 ...with ...

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Role of 3D Hypofractionated Radiotherapy in Treatment of High Grade Gliomas: A Prospective Study

Role of 3D Hypofractionated Radiotherapy in Treatment of High Grade Gliomas: A Prospective Study

... survival after surgery alone is approximately 4 months, indicating the need for more efficient and tolerable treatment alternatives (3). Radiotherapy has been the most effective treatment for these aggressive lesions, ...

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Overexpression of TELO2 decreases survival in human high- grade gliomas

Overexpression of TELO2 decreases survival in human high- grade gliomas

... High-grade gliomas are characterized with poor ...in high- grade ...of high-grade gliomas is still not yet ...with high-grade ...(WHO) grade IV ...

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Favorable Ki 67 immunohistochemical Expression in low grade and high grade gliomas

Favorable Ki 67 immunohistochemical Expression in low grade and high grade gliomas

... various gliomas to differentiated low grade and high ...low grade glioma (23 Pilocytic Astrocytoma,12 Diffuse Astrocytoma, 13 Ependymoma, 5 Oligodendroglioma, 2 Diffuse Fibrillary Astrocytoma, ...

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The Challenges of Management of High-grade Gliomas in Nigeria.

The Challenges of Management of High-grade Gliomas in Nigeria.

... Background: High-grade gliomas (HGG) are among the most challenging brain tumors despite many research efforts ...of gliomas with male:female ratio of ...Organization Grade IV ...

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Peritumoral Diffusion Tensor Imaging of High Grade Gliomas and Metastatic Brain Tumors

Peritumoral Diffusion Tensor Imaging of High Grade Gliomas and Metastatic Brain Tumors

... High-grade gliomas and metastatic tumors often contain signal intensity heterogeneity secondary to necrosis and susceptibility ...both high-grade gliomas and metastatic tumors ...

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Dendritic cell vaccines for high-grade gliomas

Dendritic cell vaccines for high-grade gliomas

... Abstract: Glioblastoma (GBM) is the most common and fatal primary adult brain tumor. To date, various promising chemotherapeutic regimens have been trialed for use in GBM; however, temo- zolomide (TMZ) therapy remains ...

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Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas

Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas

... Pediatric high-grade gliomas (pHGGs) are aggressive neoplasms representing approximately 20% of brain tumors in children. Current therapies offer limited disease control, and patients have a poor ...

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Altered splicing leads to reduced activation of CPEB3 in high-grade gliomas

Altered splicing leads to reduced activation of CPEB3 in high-grade gliomas

... of gliomas–most frequent of intracranial tumors found in ...in gliomas correlated with the rising grade of tumor ...in high-grade gliomas is caused by expression of alternatively ...

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MR Imaging Correlates of Survival in Patients with High Grade Gliomas

MR Imaging Correlates of Survival in Patients with High Grade Gliomas

... tic gliomas had much lower rates of enhancement and imaging evidence of necrosis—56% and 20%, respec- tively—than ...patients. Grade III glioma patients with enhancing tumor had a median survival of 694 ...

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Preoperative grading of glioma malignancy with thallium 201 single photon emission CT: comparison with conventional CT

Preoperative grading of glioma malignancy with thallium 201 single photon emission CT: comparison with conventional CT

... of gliomas, because thallium is taken up by ma- lignant glioma cells (3, ...is high (89%), and there is a strong statistical dif- ference between the thallium index in high- grade ...

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Dynamic Contrast enhanced T2* weighted MR Imaging of Tumefactive Demyelinating Lesions

Dynamic Contrast enhanced T2* weighted MR Imaging of Tumefactive Demyelinating Lesions

... as high-grade ...and high-grade glial neoplasms: hypercel- lularity; pleomorphic reactive astrocytes with large, hyperchromatic nuclei; mitotic figures; presence of necrotic areas; and areas ...

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Diagnostic Accuracy of Dynamic Contrast Enhanced MR Imaging Using a Phase Derived Vascular Input Function in the Preoperative Grading of Gliomas

Diagnostic Accuracy of Dynamic Contrast Enhanced MR Imaging Using a Phase Derived Vascular Input Function in the Preoperative Grading of Gliomas

... the phase-derived VIF with the bookend T1 measurement tech- nique can be used to differentiate low-grade from high-grade gliomas. This novel method can be implemented by using either a 2D or a ...

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Prognostic Factors and Treatment Outcome in Glial Brain Tumors; Data from the Third Neuro-oncology Scientific Club’s Input Forum, 2013, Mashhad, Iran

Prognostic Factors and Treatment Outcome in Glial Brain Tumors; Data from the Third Neuro-oncology Scientific Club’s Input Forum, 2013, Mashhad, Iran

... in high-grade gliomas and some interdisciplinary practical discussions, part of the meeting was dedicated to updating the members with the interim results of the neuro-oncology clinical ...

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Diagnostic Accuracy of Neuroimaging to Delineate Diffuse Gliomas within the Brain: A Meta Analysis

Diagnostic Accuracy of Neuroimaging to Delineate Diffuse Gliomas within the Brain: A Meta Analysis

... Inherent in any regional treatment, such as surgery and radi- ation therapy, is the need to delineate a target volume, which mandates a dichotomous classification into tumor and normal tissue. Low- and ...

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Dynamic Susceptibility Contrast Enhanced Perfusion and Conventional MR Imaging Findings for Adult Patients with Cerebral Primitive Neuroectodermal Tumors

Dynamic Susceptibility Contrast Enhanced Perfusion and Conventional MR Imaging Findings for Adult Patients with Cerebral Primitive Neuroectodermal Tumors

... as gliomas, lympho- mas, and tumefactive demyelinating ...in high grade gliomas. The relative high cellularity and resultant iso- to hypointensity on T2-weighted images sometimes makes ...

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Preoperative Grading of Presumptive Low Grade Astrocytomas on MR Imaging: Diagnostic Value of Minimum Apparent Diffusion Coefficient

Preoperative Grading of Presumptive Low Grade Astrocytomas on MR Imaging: Diagnostic Value of Minimum Apparent Diffusion Coefficient

... benign grade for which, typically, the survival exceeds 5 years and the postoperative survival usually ranges from 3 to 10 ...Conversely, high-grade astrocytic tumors have poor ...and ...

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Glioma Grading: Sensitivity, Specificity, and Predictive Values of Perfusion MR Imaging and Proton MR Spectroscopic Imaging Compared with Conventional MR Imaging

Glioma Grading: Sensitivity, Specificity, and Predictive Values of Perfusion MR Imaging and Proton MR Spectroscopic Imaging Compared with Conventional MR Imaging

... low- grade gliomas is the same as that of misclassifying high-grade gliomas and the two are equally likely to be presented to you for ...and high-grade gliomas in ...

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The Complexities of Resistance to Bevacizumab

The Complexities of Resistance to Bevacizumab

... Glioblastoma is a highly malignant primary tumor of the central nervous system tumor with a poor survival rate. The treatment of glioblastoma is shifting from a purely cytotoxic approach to one that incorporates ...

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Diffusion Tensor MR Imaging of High Grade Cerebral Gliomas

Diffusion Tensor MR Imaging of High Grade Cerebral Gliomas

... Therefore, highlighting why the differentiation of abnormal tissue from apparently normal tissue was possible in the current study is important. In our study, all of the patients examined had newly diag- nosed ...

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