High-risk human papillomavirus 16
Nuclear Entry of High-Risk Human Papillomavirus Type 16 E6 Oncoprotein Occurs via Several Pathways
... [IPTG] at 30°C), and the soluble His-tagged proteins were purified in their native state on Talon beads using a standard procedure. GST-Kap 1 (5) and GST-Kap 2 (6) were expressed in E. coli BL21(DE3) (3-h induction ...
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Modulation of microRNA mRNA Target Pairs by Human Papillomavirus 16 Oncoproteins
... by high-risk human papillomaviruses ...of human foreskin keratinocytes (HFKs) with stable expression of HPV16 E6/E7 or a control ...the high-risk HPV E6 and E7 proteins that ...
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Molecular characterization of high risk human papillomavirus genotypes involved in invasive cervical cancer from formalin fixed, paraffin embedded tissues in Ouagadougou, Burkina faso
... HPV 16 and 18 were detected in ...HPV 16 and 18 namely HPV31, 35, 39, 45, 51, 52, 56, 58 and 59 were therefore more common in both squamous cell carcinomas and ...
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Anal high-risk human papillomavirus infection and high-grade anal intraepithelial neoplasia detected in women and heterosexual men infected with human immunodeficiency virus
... was done according to the manufacturer’s instructions on the anal cytology specimen using the Hybrid Capture 2 assay (Qiagen Corporation, Gaithersburg, MD, USA). The Hybrid Capture 2 assay utilizes probes for 13 types of ...
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Genetic variations in E6, E7 and the long control region of human papillomavirus type 16 among patients with cervical lesions in Xinjiang, China
... with high-risk human papilloma- virus (HR-HPV) (such as HPV16 and HPV18) can lead to atypical hyperplasia and cancer in the cervix, thus confirming HPV as a central cause of this malignant tumor ...
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Human papillomavirus type 16 E6 variants in France and risk of viral persistence
... High-risk (HR) human papillomaviruses (HPVs), are the etiological agents of cervical cancer [1]. Even though in- fection with an HR-HPV is frequent in sexually active women, the majority of ...
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Human papillomavirus infection in anal intraepithelial lesions from HIV infected Cuban men
... Persistent human papillomavirus (HPV) infection, es- pecially high-risk HPV (HR-HPV) viral types such as HPV- 16 and HPV- 18, is associated with anal cancer and its precursor lesions, ...
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Worldwide Genomic Diversity of the High-Risk Human Papillomavirus Types 31, 35, 52, and 58, Four Close Relatives of Human Papillomavirus Type 16
... described human papillomavirus (HPV) types, 18 are referred to as high-risk HPV types due to their association with anogenital ...a 16-bp insert in select variants of HPV-35, which ...
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Risk of Human Papillomavirus (HPV) Infection and Cervical Neoplasia after Pregnancy
... included high oncogenic risk (HR-) HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68, 73 and 82, and low oncogenic risk (LR-) HPV types 6, 11, 26, 32, 34, 40, 42, 44, 53, 54, ...
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Clinical Performance of Human Papillomavirus E6 and E7 mRNA Testing for High Grade Lesions of the Cervix
... HPV DNA detection and genotyping. HPV DNA detection was performed with the Hybrid Capture II system (HC2; Digene), according to the manufacturer’s directions. HC2 is a nonradioactive signal amplification method based on ...
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Low avidity of human papillomavirus (HPV) type 16 antibodies is associated with increased risk of low risk but not high risk HPV type prevalence
... increased risk of acquiring other HPVs ...Sexual risk-taking behavior also predisposes women to various HPV types earlier in Uganda than in Finland ...increased risk of HPV6 or 11 ...
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Comparison of Human Papillomavirus Detection by Aptima HPV and cobas HPV Tests in a Population of Women Referred for Colposcopy following Detection of Atypical Squamous Cells of Undetermined Significance by Pap Cytology
... HPV 16 18/45 genotype assay (AHPV GT) for high-risk human papillomavirus (hrHPV) detection, clinical performance in detecting cervical intraepithelial neoplasia grade 2 (CIN2) or more ...
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E6^E7, a Novel Splice Isoform Protein of Human Papillomavirus 16, Stabilizes Viral E6 and E7 Oncoproteins via HSP90 and GRP78
... from high-risk, 4 from possibly high-risk, 8 from low-risk, and 11 from risk-undetermined HPVs), of which 8 are high-risk HPVs (HPV16, -18, -31, -39, -45, -56, -59, ...
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Genotyping of high risk anal human papillomavirus (HPV): ion torrent next generation sequencing vs linear array
... a human β-globin internal control target. Both high- and low-risk HPV genotypes were detected using the LA (Roche Diagnostics, Indianapolis ...IN). High-risk HPV in- cluded 13 type ...
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High risk human papillomavirus prevalence and genotype distribution among women infected with HIV in Manaus, Amazonas
... In the present study we found a clear association be- tween weakened immune status and infection by HR- HPV. In most studies of HIV and HPV, the magnitude of increased HPV prevalence was proportional to the se- verity of ...
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Comparison of the Abbott RealTime High Risk Human Papillomavirus (HPV), Roche Cobas HPV, and Hybrid Capture 2 Assays to Direct Sequencing and Genotyping of HPV DNA
... Compared with changes in cervical cytology, HPV DNA can be detected earlier and is identifiable for a longer time (30). Previous randomized trials also reported the usefulness of HPV-based screening tests in cervical ...
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Safety and immunogenicity of the quadrivalent human papillomavirus (qHPV) vaccine in HIV-positive Spanish men who have sex with men (MSM)
... quadrivalent human papillomavirus (qHPV) vaccine carried-out in HIV seronegative ...at risk, vs. in HM 0.08/100 person-year at risk) [22], and a lower antibody response against the qHPV ...
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Serological Detection of Human Papillomavirus Type 16 Infection in Human Immunodeficiency Virus (HIV)-Positive and High-Risk HIV-Negative Women
... Study population. The Women’s Interagency HIV Study (WIHS) is a multi- center prospective cohort study consisting of 2,059 HIV-positive and 569 HIV- negative women enrolled from 1994 to 1995. At baseline and at each ...
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Agreement between the AMPLICOR Human Papillomavirus Test and the Hybrid Capture 2 Assay in Detection of High Risk Human Papillomavirus and Diagnosis of Biopsy Confirmed High Grade Cervical Disease
... with human papillomavirus (HPV) has been de- tected in 95 to 100% of cervical cancers, the second most common female cancer worldwide (30), and persistent infec- tion with high-risk HPV ...
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Molecular Pap smear: HPV genotype and DNA methylation of ADCY8, CDH8, and ZNF582 as an integrated biomarker for high-grade cervical cytology
... of human papillomavirus (HPV)-16 from cervical carcinoma by zur Hausen et ...primary high-risk HPV (hrHPV) cervical screening and alternative strategies that supplant the ...
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