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Homeotic (HOX) gene

Evolving expression patterns of the homeotic gene Scr in insects

Evolving expression patterns of the homeotic gene Scr in insects

... the homeotic (hox) gene Sex combs reduced ...this gene is crucial in establishing the identity of the labial segment, suppressing wing formation on the prothorax (T1), and directing the ...

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Transvection and Silencing of the Scr Homeotic Gene of Drosophila melanogaster

Transvection and Silencing of the Scr Homeotic Gene of Drosophila melanogaster

... (Scr) gene specifies the identities of the labial and first thoracic segments in Drosophila ...Scr gene is blocked by rearrangements that disrupt pairing, but is zeste ...Scr gene in the second and ...

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The regulation of Hox gene expression during animal development

The regulation of Hox gene expression during animal development

... Ubx gene expression during appendage development (Ronshaugen et ...evident homeotic transformation in the haltere or elsewhere in the developing fly (Bender, 2008; Thomsen et ...of Hox regulation by ...

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The significance of Hox gene collinearity

The significance of Hox gene collinearity

... vertebrate Hox genes. Thus, in situ hybridization studies showed that Hox genes of mice are similarly expressed in partially overlap- ping domains along the head-tail axis, and the location of genes along ...

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Initiation, establishment and maintenance of Hox gene expression patterns in the mouse

Initiation, establishment and maintenance of Hox gene expression patterns in the mouse

... of Hox gene expression domains A possible role of RA in modulating the expression domains of the Hox genes during embryogenesis was suggested by Kessel and Gruss ...posterior homeotic-like ...

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Vertebrate GAGA factor associated insulator elements demarcate homeotic genes in the HOX clusters

Vertebrate GAGA factor associated insulator elements demarcate homeotic genes in the HOX clusters

... of Hox expression have not been ...murine Hox genes suggest sites of potential regulatory function that could help demarcate their domains of ...regulate Hox clusters ...murine Hox clusters ...

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Investigating the functional significance of evolutionarily conserved protein motifs of the Drosophila melanogaster HOX protein, Sex combs reduced

Investigating the functional significance of evolutionarily conserved protein motifs of the Drosophila melanogaster HOX protein, Sex combs reduced

... the Homeotic selector (Hox) genes. In Drosophila melanogaster, Hox gene expression in spatially restricted domains along the A-P axis of the embryo determines segmental ...of HOX ...

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Schmähling, Sigrun
  

(2019):


	Biochemical purification and functional characterization of a novel trithorax-group protein complex.


Dissertation, LMU München: Fakultät für Biologie

Schmähling, Sigrun (2019): Biochemical purification and functional characterization of a novel trithorax-group protein complex. Dissertation, LMU München: Fakultät für Biologie

... entwicklungsregulatorischer Gene im Körperbauplan vielzelliger Organismen verantwortlich ...sind HOX-Gene. HOX-Gene codieren wiederum für Transkriptionsfaktoren, die innerhalb ihrer ...

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Onychophoran Hox genes and the evolution of arthropod Hox gene expression

Onychophoran Hox genes and the evolution of arthropod Hox gene expression

... segmentation gene cascade reviewed in ...the Hox genes, which in turn specify segmen- tal ...the Hox genes are involved in providing positional information in a combinatorial mode to give each ...

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Regulation of mouse Hoxb-4 expression during embryogenesis

Regulation of mouse Hoxb-4 expression during embryogenesis

... MU gene has been disrupted by gene targeting (Yu et a l, ...bidirectional homeotic transformations of the axial skeleton as well as sternal ...representative Hox genes, Hoxa-7 and Hoxc-9, are ...

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Hox gene function and cell identity in Drosophila

Hox gene function and cell identity in Drosophila

... The Drosophila Hox genes are expressed in precise segmental domains (Figure 1.2), suggesting that their downstream targets would also be differentially expressed between segments. Based on this assumption, two ...

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Wnt signaling is a key mediator of Cdx1 expression in vivo

Wnt signaling is a key mediator of Cdx1 expression in vivo

... the Hox gene products are crucial mediators of AP vertebral ...murine Hox genes are distributed in four clusters, Hoxa to Hoxd, which are likely to have arisen from duplication of an ancestral ...

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A comprehensive catalog of post-translational modifications of Drosophila melanogaster HOX protein, Sex combs reduced

A comprehensive catalog of post-translational modifications of Drosophila melanogaster HOX protein, Sex combs reduced

... The Hox genes provide an example of extensive conservation. Primitive Hox clusters are found in the diploblastic Cnidarian lineage, but not in Ctenophores, Placozoa or Porifera lineages (Murtha et ...A ...

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Is Function of the Drosophila Homeotic Gene Ultrabithorax Canalized?

Is Function of the Drosophila Homeotic Gene Ultrabithorax Canalized?

... This observation does not, however, necessarily imply that the traits are under control of different genes, as fine structure analy- sis indicates that the same alleles can [r] ...

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Segment specific prevention of pioneer neuron apoptosis by cell autonomous, postmitotic Hox gene activity

Segment specific prevention of pioneer neuron apoptosis by cell autonomous, postmitotic Hox gene activity

... on Hox function, their late, segment- specific survival is under homeotic control; the Hox gene Abdominal B (Abd-B) acts in posterior segments in a cell- autonomous and postmitotic fashion to ...

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Genetic Analysis of the Bone Morphogenetic Protein-Related Gene, gbb, Identifies Multiple Requirements During Drosophila Development

Genetic Analysis of the Bone Morphogenetic Protein-Related Gene, gbb, Identifies Multiple Requirements During Drosophila Development

... melanogaster gene glass bottom boat (gbb), which encodes a TGF-b signaling molecule (formerly referred to as 60A) with highest sequence similarity to members of the bone morphogenetic protein (BMP) subgroup ...

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The lawc Gene Is a New Member of the trithorax-Group That Affects the Function of the gypsy Insulator of Drosophila

The lawc Gene Is a New Member of the trithorax-Group That Affects the Function of the gypsy Insulator of Drosophila

... lawc gene result in a pleiotropic phenotype that includes homeotic transformation of the arista into ...affect homeotic gene transcription, causing ectopic expression of Antennapedia in the ...

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Composition and genomic organization of arthropod Hox clusters

Composition and genomic organization of arthropod Hox clusters

... of Hox gene duplications were identified in ...tandem gene duplication located in an arthropod Hox cluster; ...complete Hox clusters ...apparent Hox gene ...

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Hox Gene Collinearity May Be Related to Noether’s Theory on Symmetry and Its Linked Conserved Quantities

Hox Gene Collinearity May Be Related to Noether’s Theory on Symmetry and Its Linked Conserved Quantities

... as Hox Gene Collinearity (HGC) can be easily incorporated in the present ...the Hox genes is a very surprising event that proved later to be a universal property widespread to most animal clades ...

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Did homeobox gene duplications contribute to the Cambrian explosion?

Did homeobox gene duplications contribute to the Cambrian explosion?

... of Hox gene clusters are especially similar in DNA sequence to Hox genes, and for some time their evolutionary origins remained ...some Hox genes than many Hox genes are to each other. ...

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