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human epidermal growth factor

The coexpression  and prognostic significance of c-MET, fibroblast growth factor receptor 2, and human epidermal growth factor receptor 2 in resected gastric cancer: a retrospective study

The coexpression and prognostic significance of c-MET, fibroblast growth factor receptor 2, and human epidermal growth factor receptor 2 in resected gastric cancer: a retrospective study

... fibroblast growth factor receptor 2 (FGFR2), and human epidermal growth factor receptor 2 (HER2) in human GC and their clinical significance in clinical therapy were ...

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Prognostic significance of Human epidermal growth factor receptor 2 expression in patients with resectable gastric adenocarcinoma

Prognostic significance of Human epidermal growth factor receptor 2 expression in patients with resectable gastric adenocarcinoma

... Human epidermal growth factor receptor 2 (HER2), a target used in breast cancer treatment, is the second member of the epidermal growth factor receptor (EGFR) family and ...

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PIK3CA mutations, phosphatase and tensin homolog, human epidermal growth factor receptor 2, and insulin like growth factor 1 receptor and adjuvant tamoxifen resistance in postmenopausal breast cancer patients

PIK3CA mutations, phosphatase and tensin homolog, human epidermal growth factor receptor 2, and insulin like growth factor 1 receptor and adjuvant tamoxifen resistance in postmenopausal breast cancer patients

... Sufficient tumor material was available for 739 patients, who did not differ in prognostic factors from the total group (see Additional file 1: Table S1). After revision of ERα status as assessed with ...

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6100.pdf

6100.pdf

... EGFR(epidermal growth factor receptor) and the related HER-2 (human epidermal growth factor receptor 2) associated with breast cancer has allowed for the development of ...

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Gene expression meta-analysis supports existence of molecular apocrine breast cancer with a role for androgen receptor and implies interactions with ErbB family

Gene expression meta-analysis supports existence of molecular apocrine breast cancer with a role for androgen receptor and implies interactions with ErbB family

... (AR): Androgen Receptor; (BCRI): Backward Chaining Rule Induction; (EGFR): Epidermal Growth Factor Recep- tor; (ER): Estrogen Receptor; (ErbB2): Human Epidermal Growth Factor Receptor 2 [r] ...

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... In a previous study [6], we analyzed the prognostic impor- tance of the circulating tumor markers (CTMs) cytokeratin 19 (CK19), CK20, epidermal growth factor receptor (EGFR) and human ...

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Triple-negative breast cancer: new perspectives for targeted therapies

Triple-negative breast cancer: new perspectives for targeted therapies

... Abstract: Breast cancer is a heterogeneous disease, encompassing a large number of entities showing different morphological features and having clinical behaviors. It has became apparent that this diversity may be ...

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Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis

Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis

... of epidermal growth factor receptors (EGFRs) or ERBB receptors has attracted great attention in the literature ...(HER1/c-erbB1), human epidermal growth factor receptor ...

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Aquaporin 3 promotes epithelial-mesenchymal transition in gastric cancer

Aquaporin 3 promotes epithelial-mesenchymal transition in gastric cancer

... GC. Human epidermal growth factor (EGF) [17] and hepatocyte growth factor (HGF) [18] up-regulate AQP3 expression via the extracellular signal-regulated kinase (ERK) pathway, then ...

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Impact of country of birth on genetic testing of metastatic lung adenocarcinomas in France : African women exhibit a mutational spectrum more similar to Asians than to Caucasians

Impact of country of birth on genetic testing of metastatic lung adenocarcinomas in France : African women exhibit a mutational spectrum more similar to Asians than to Caucasians

... Abbreviations NSCLC: non-small cell lung cancer; EGFR: epidermal growth factor receptor; ERBB2: human epidermal growth factor receptor 2 avian erythroblastosis oncogene B2 homolog; KRAS:[r] ...

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Metastasizing Maxillary Ameloblastoma: Report of a Case with Molecular Characterization

Metastasizing Maxillary Ameloblastoma: Report of a Case with Molecular Characterization

... a human epidermal growth factor receptor belonging to the same family of EGFR and its protein overexpression has been found in several carcinomas ...

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The progress of targeted therapy in advanced gastric cancer

The progress of targeted therapy in advanced gastric cancer

... Approximately one million people are diagnosed each year with gastric cancer, making it the fourth most com- mon cancer and the second leading cause of cancer re- lated death worldwide with an estimated 800,000 deaths ...

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Role of lapatinib in the first-line treatment of patients with metastatic breast cancer

Role of lapatinib in the first-line treatment of patients with metastatic breast cancer

... Abstract: Lapatinib is a dual tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR/ErbB1) and human epidermal growth factor receptor 2 (HER2/ErbB2). EGFR ...

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The non-small cell lung cancer EGFR extracellular domain mutation, M277E, is oncogenic and drug-sensitive

The non-small cell lung cancer EGFR extracellular domain mutation, M277E, is oncogenic and drug-sensitive

... the epidermal growth factor receptor (EGFR) kinase domain, the human epidermal growth factor receptor 2 kinase domain, as well as the KRAS, BRAF, ALK, ROS1 and RET ...

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Mutations in the phosphatidylinositol 3 kinase pathway: role in tumor progression and therapeutic implications in breast cancer

Mutations in the phosphatidylinositol 3 kinase pathway: role in tumor progression and therapeutic implications in breast cancer

... phosphatidylinositol 3-kinase (PI3K) pathway occur in >70% of breast cancers. Clinical and experimental evidence suggest that PI3K pathway activation promotes resistance to some of the current breast cancer therapies. ...

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In silico identification of EGFR-T790M inhibitors with novel scaffolds: start with extraction of common features

In silico identification of EGFR-T790M inhibitors with novel scaffolds: start with extraction of common features

... Background: Epidermal growth factor receptor (EGFR) is an attractive therapeutic target for a number of human tumors including non-small cell lung cancer ...

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Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha

Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha

... The epidermal growth factor (EGF) receptor is activated by both EGF and transforming growth factor-alpha ...normal human pancreas, and that all three proteins are expressed at ...

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Actions of growth factors on plasma calcium  Epidermal growth factor and human transforming growth factor alpha cause elevation of plasma calcium in mice

Actions of growth factors on plasma calcium Epidermal growth factor and human transforming growth factor alpha cause elevation of plasma calcium in mice

... Certain growth factors (such as epidermal growth factor, platelet-derived growth factor, and transforming growth factors-alpha and -beta) have been shown to stimulate the ...

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Does consuming isoflavones reduce or increase breast cancer risk?

Does consuming isoflavones reduce or increase breast cancer risk?

... from human intervention studies have been less ...and growth vary between different ...of human interventions, have led to a controversy surrounding the intake of isoflavone to reduce breast cancer ...

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Liver-derived human mesenchymal stem cells: a novel therapeutic source for liver diseases

Liver-derived human mesenchymal stem cells: a novel therapeutic source for liver diseases

... Similar to MSCs from other tissues, LHMSCs have the capacity for self-renewal, multipotent differentiation, and immunosuppression. LHMSCs exhibit high proliferative ability in long-term culture, and Wnt signaling has ...

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