Human mesenchymal stem cells (hMSCs)
Localization of Human Mesenchymal Stem Cells from Umbilical Cord Blood and Their Role in Repair of Diabetic Foot Ulcers in Rats
... of human mesenchymal stem cells from umbilical cord matrix (hMSCs-UC) and the role of these cells in the repair of foot ulcerate tissue in diabetic foot ulcers in ...weeks. ...
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Nanog overexpression allows human mesenchymal stem cells to differentiate into neural cells——Nanog transdifferentiates mesenchymal stem cells
... Although stem cell therapies have been proposed as a candidate for treating neurological diseases, the best stem cell source and their therapeutic efficacy remain ...Embryonic stem cells ...
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<p>Functionalized Graphene Nanoparticles Induce Human Mesenchymal Stem Cells to Express Distinct Extracellular Matrix Proteins Mediating Osteogenesis</p>
... content, human fat-derived MSCs express and secrete a discrete and organized pattern of bone-speci fi c ECM proteins within 24 hrs post ...of hMSCs with- out any contribution from the FBS present in the ...
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Bioprocessing strategies for the large-scale production of human mesenchymal stem cells: a review
... of hMSCs may alter their phenotype and therapeutic proper- ties as it represents an environment which is a different from their niche in vivo ...pre-conditioning hMSCs with either biological factors or the ...
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SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells
... modify hMSCs at very high efficiencies and for extended periods without affecting their potential for dif- ferentiation ...of hMSCs in suitable aggregate cultures, with an increased production of major ...
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Human mesenchymal stem cells maintain their phenotype, multipotentiality, and genetic stability when cultured using a defined xeno-free human plasma fraction
... for hMSCs culture and expansion and is being used in many studies, some drawbacks are coming out, such as donor variability [45], decreased expression of adipogenic and osteogenic differentiation markers [46, 47], ...
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Labeling Human Mesenchymal Stem Cells with Gold Nanocages for in vitro and in vivo Tracking by Two-Photon Microscopy and Photoacoustic Microscopy
... the cells based on their two-photon luminescence intensity or pho- toacoustic ...daughter cells when the mother cells ...daughter cells upon the division of the mother ...by hMSCs were ...
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Heart on a chip: Micro-nanofabrication and microfluidics steering the future of cardiac tissue engineering
... using human umbilical vein endothelial cells (HUVECs) and human mesenchymal stem cells (hMSCs) on a defined ...heart. Cells were integrated into the vessels of the ...
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Differential redox potential profiles during adipogenesis and osteogenesis
... multipotent human mesenchymal stem cells (hMSCs) that are capable of differentiating into many different phenotypes in vitro, including osteoblasts and adipocytes [8], as a more ...
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Assessment of Migration of Human MSCs through Fibrin Hydrogels as a Tool for Formulation Optimisation
... for cells to provide any therapeutic effect, they must migrate out from the delivery ...encapsulated human mesenchymal stem cells (hMSCs) from a cell spheroid through fibrin ...
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LAMA2 regulates the fate commitment of mesenchymal stem cells via hedgehog signaling
... and human mesenchymal stem cells (hMSCs) are the ideal seed cells for bone tissue engineering due to their multi-lineage differentiation potential and ...of mesenchymal ...
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Comparative studies on thin polycaprolactone-tricalcium phosphate composite scaffolds and its interaction with mesenchymal stem cells
... Method: Thin biodegradable poly( ε -caprolactone) (PCL) based hybrid scaffolds were developed in combination with α -tricalcium phosphate (TCP) particles, gelatin and fibronectin separately and the fabricated scaffolds ...
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Overexpression of hTERT increases stem-like properties and decreases spontaneous differentiation in human mesenchymal stem cell lines
... of stem-like properties and spontaneous differentiation those hinder the expansion and applica- tion of human mesenchymal stem cells (hMSCs), we have clonally isolated permanent ...
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A novel bispecific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells to target blood vessels and vasculogenic mimicry of malignant gliomas
... in hMSCs via lentiviral transduction, cells were incubated with VEGF 165 -ephrin A1-PE38KDEL lentivirus at 100 MOI, and untransduced hMSCs were used as the ...of hMSCs, as shown in Figure ...
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Role of the P2X7 receptor in the osteogenic differentiation of mesenchymal cells and in osteoclast fusion
... of hMSCs in ...in human MSC, the P2X7 receptor has been previously shown to play a role in the balance of pro-survival or pro-death signals in mouse embryonic stem cells ...in stem cell ...
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CCL1 blockade alleviates human mesenchymal stem cell (hMSC)-induced pulmonary fibrosis in a murine sclerodermatous graft-versus-host disease (Scl-GVHD) model
... T cells in vitro ...that hMSCs would mitigate the severity of Scl-GVHD in mice after ...reveal hMSCs to effect- ively diminish Scl-GVHD in skin tissue; dissimilarly, hMSCs resulted in a ...
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Unveiling mesenchymal stromal cells’ organizing function in regeneration
... Multilineage potential of adult human mesenchymal stem cells. A., Mesenchymal stem cells in tissue growth and repair[r] ...
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Original Article Calcium sulfate cement combined with silica-based mesoporous material for bone regeneration: in vitro and in vivo study
... osteogenic cells as well as the ability to repair bone defects in vivo still remains ...of human bone marrow mesenchymal stem cells (hMSCs), inc- luding the cell adhesion, ...
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MicroRNA-181c prevents apoptosis by targeting of FAS receptor in Ewing’s sarcoma cells
... technology. Human Ewing sarcoma cells (SK-N-MC, RD-ES, SK-ES-1 and SCCH) were purchased from Japa- nese Collection of Research Bioresources (Tokyo, ...a human ES cell line, was generously provided by ...
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Nonadherent culture method promotes MSC-mediated vascularization in myocardial infarction via miR-519d/VEGFA pathway
... years, stem cell therapy has become a promising approach to treat MI, as it has the potential to restore damaged myocardium [3, ...4]. Mesenchymal stem cells (MSCs) exist in the bone mar- row, ...
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