Human rhinoviruses (HRVs)
Human rhinoviruses: coming in from the cold
... Human rhinoviruses (HRVs) are the most common cause of acute respiratory tract illness globally [1], infecting both upper and lower respiratory tract tissues ...
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Real Time Reverse Transcription PCR Assay for Comprehensive Detection of Human Rhinoviruses
... Human rhinoviruses (HRVs) are important contributors to respiratory disease, but their healthcare burden remains unclear, primarily because of the lack of sensitive, accurate, and convenient means of ...
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Antiviral Effects of Pyrrolidine Dithiocarbamate on Human Rhinoviruses
... Human rhinoviruses (HRVs), the main causative agents of the common cold occurring worldwide (20), constitute the most extensive genus of the Picornaviridae. The frequent ap- pearance of HRV infections and ...
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Major and Minor Receptor Group Human Rhinoviruses Penetrate from Endosomes by Different Mechanisms
... Intercellular adhesion molecule 1 and the low-density lipoprotein receptor are used for cell entry by major and minor receptor group human rhinoviruses (HRVs), respectively. Whereas minor-group viruses, ...
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Molecular detection of human rhinoviruses in respiratory samples: a comparison of Taqman probe , SYBR green I and BOXTO based real time PCR assays
... In conclusion, this study confirms the difficulty in detecting HRVs in clinical samples using a single molecular detection system. Besides the possible utilisation of distinct pairs of primers to adequately cover the ...
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Screening Respiratory Samples for Detection of Human Rhinoviruses (HRVs) and Enteroviruses: Comprehensive VP4 VP2 Typing Reveals High Incidence and Genetic Diversity of HRV Species C
... (ARTIs). Human rhinoviruses (HRVs) are classified into two species, species A and B, which contain over 100 serotypes, and a recently discovered genetically hetero- geneous third species (HRV species ...
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Superiority of Digital Reverse Transcription PCR (RT PCR) over Real Time RT PCR for Quantitation of Highly Divergent Human Rhinoviruses
... ABSTRACT Human rhinoviruses (HRV) comprise 3 species representing more than 150 ...important human respiratory pathogen, molecular detection is an indispensable tool for diagnosis and ...
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Isolation of a monoclonal antibody that blocks attachment of the major group of human rhinoviruses.
... This was shown by reciprocal competition binding assays 1, 12 and by isolation of a mouse monoclonal antibody capable of blocking infection of HeLa cells by the major group of HRVs.. Thr[r] ...
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Antiviral activity and possible mode of action of ellagic acid identified in Lagerstroemia speciosa leaves toward human rhinoviruses
... is between 0.22 and 294.55 μM. Ellagic acid exhibited greater antiviral activity than ribavirin toward three HRVs and high selectivity. This original finding indicates that materials derived from L. speciosa leaves can ...
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Human major group rhinoviruses downmodulate the accessory function of monocytes by inducing IL 10
... Human rhinoviruses (HRVs) are the predominant cause of the common cold. Although this disease is per se rather harmless, HRV infection is considered to set the stage for more dangerous pathogens in vivo. ...
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Lack of a Close Relationship Between Three Strains of Human Rhinoviruses as Determined by Their RNA Sequences
... Native virions of HRV 1A, HRV 2, and HRV 14 were permitted to react with high titer antisera which were produced against the native virions of these types, and the results confirm the ab[r] ...
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Broad Neutralization of Human Immunodeficiency Virus Type 1 (HIV-1) Elicited from Human Rhinoviruses That Display the HIV-1 gp41 ELDKWA Epitope
... In this study, we focused our attention on presenting part of the membrane-proximal external region (MPER) of the trans- membrane glycoprotein gp41, a region of approximately 30 amino acids adjacent to the transmembrane ...
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Isolation of a receptor protein involved in attachment of human rhinoviruses.
... Similar to the receptor antibody, the polyclonal antiserum was able to selectively protect HeLa cell monolayers from infection by HRV-14 and HRV-15 major HRV group and coxsackie A13 viru[r] ...
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Human Rhinoviruses in Korean with Acute Low Respiratory Tract Infections
... showed that among the 27 isolates with HRV, 14 (52%) were infected with species A, 2 (7%) were infected with species B, and 11 (41%) were infected with the strains from HRV-C. The alignment of the sequences in the ...
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The ABCs of Rhinoviruses, Wheezing, and Asthma
... Virology and clinical textbooks and virtually all web-based information sources generally describe human rhinoviruses (HRVs) as the most frequent cause of the common cold. In this light, HRVs are important ...
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Human Rhinoviruses in Severe Respiratory Disease in Very Low Birth Weight Infants
... METHODS: A 2-year prospective cohort study was conducted among VLBW premature infants in Buenos Aires, Argentina. Infants were enrolled in the NICU from June 1, 2003, to May 31, 2005, and managed monthly and with every ...
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Characterization of human rhinoviruses displaced by an anti-receptor monoclonal antibody.
... Percentage of radioactively labeled virus displaced from membranes by incubation with PBS or with anti-receptor antibody Virus serotype and radioactive precursor % of viruses displaced" [r] ...
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Human rhinoviruses and enteroviruses in influenza like illness in Latin America
... [30,31], human metapneumovirus [32,33], respira- tory syncytial virus [30,31], and adenovirus [31,34] in the region, emphasizing the potential clinical and public health importance of this ...
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New Molecular Detection Tools Adapted to Emerging Rhinoviruses and Enteroviruses
... Human rhinoviruses (HRV), and to a lesser extent human enteroviruses (HEV), are important respi- ratory pathogens. Like other RNA viruses, these picornaviruses have an intrinsic propensity to ...
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Human rights and human development: a conceptual framework for research
... of human rights in general and in the success of ...The Human Development Report 2000 combines this under-standing of human development as the enhancement of capabilities with the concept of basic ...
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