human T-cell leukemia virus
The tax gene of human T-cell leukemia virus type 2 is essential for transformation of human T lymphocytes.
... of human T-cell leukemia virus (HTLV)-mediated transformation and induction of malig- nancy is unknown; however, several studies have implicated the viral gene product, ...infectious ...
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Human T cell leukemia virus type I infects human lung epithelial cells and induces gene expression of cytokines, chemokines and cell adhesion molecules
... Human T-cell leukemia virus type I (HTLV-I) is a retrovi- rus responsible for adult T-cell leukemia (ATL) [1] and a chronic neurological disorder known as ...
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Transmission of Human T-Cell Leukemia Virus Type 1 to Mice
... Human T-cell leukemia virus type 1 (HTLV-1) is known to be associated with the pathogenesis of adult T-cell leukemia (ATL) (5, 8, 29, 30, 39, 44), HTLV-1-associated ...
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A Human T-Cell Leukemia Virus Type 1 Regulatory Element Enhances the Immunogenicity of Human Immunodeficiency Virus Type 1 DNA Vaccines in Mice and Nonhuman Primates
... from human T-cell leukemia virus type 1 (HTLV-1) to the cytomegalovirus (CMV) enhancer/promoter increased transgene expression 5- to 10-fold and improved cellular immune re- sponses to ...
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Superoxide-Generating Nox5α Is Functionally Required for the Human T-Cell Leukemia Virus Type 1-Induced Cell Transformation Phenotype
... Human T-cell leukemia virus type 1 (HTLV-1) is associated with adult T-cell leukemia (ATL) and transforms T cells in ...HTLV-1-transformed cell lines, ...
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Effector domains of human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex are functionally interchangeable and share an essential peptide motif.
... 6001-6007 0022-538X/91/116001-07$02.00/0 Copyright C 1991, American Society for Microbiology Effector Domains of Human Immunodeficiency Virus Type 1 Rev and Human T-Cell Leukemia Virus T[r] ...
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Human T-Cell Leukemia Virus Type 1 Expressing Nonoverlapping Tax and Rex Genes Replicates and Immortalizes Primary Human T Lymphocytes but Fails To Replicate and Persist In Vivo
... Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus associated primarily with adult T-cell leukemia and neurological ...primary T cells, ...
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Prevention of Adult T-Cell Leukemia-Like Lymphoproliferative Disease in Rats by Adoptively Transferred T Cells from a Donor Immunized with Human T-Cell Leukemia Virus Type 1 Tax-Coding DNA Vaccine
... Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) in infected individuals after a long incubation ...immune T cells on the ...
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Human T cell leukemia virus type I (HTLV I) infection and the onset of adult T cell leukemia (ATL)
... After HTLV-I infection, viral proteins such as Tax protein promote the proliferation of infected cells and also inhibit apoptosis by their pleiotropic actions. Since the HTLV-I provirus is randomly integrated into the ...
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APOBEC3G targets human T cell leukemia virus type 1
... (pNL43-Luc or pNL43/∆vif-Luc, respectively) with or without an expression vector for HA-APOBEC3G and per- formed Western blotting to detect APOBEC3G in pro- ducer cells and produced virions. Incorporation of APOBEC3G was ...
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Oncoviral Bovine Leukemia Virus G4 and Human T-Cell Leukemia Virus Type 1 p13II Accessory Proteins Interact with Farnesyl Pyrophosphate Synthetase
... FPPS interaction was, however, obtained by means of a pri- mary cell immortalization assay. One of the most interesting issues of this work indeed concerns the biological relevance of the G4-FPPS interaction ...
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Molecular biology of the type I human T cell leukemia virus (HTLV I) and adult T cell leukemia
... Abbreviations used in this paper: ATF, activating transcription factor; ATLL, adult T-cell leukemia/lymphoma; CREB, cyclic ANMP response element binding protein; HTLV-I, type I human T-c[r] ...
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TM domain swapping of murine leukemia virus and human T-cell leukemia virus envelopes confers different infectious abilities despite similar incorporation into virions.
... the cell- to-cell fusion ...a cell-free assay on permissive ...various cell lines (7, 11). However, HTLV-1 Env is highly fusogenic for many cell lines in cell-to-cell ...
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Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV 1) tax protein or virus transformed cells
... transformed human lymphoid lines, but not in thymocytes from Thy-tax transgenic ...fibroblastic cell line and Jak3 in HTLV-1 transformed human T cell ...
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Inhibition of constitutively active Jak Stat pathway suppresses cell growth of human T cell leukemia virus type 1 infected T cell lines and primary adult T cell leukemia cells
... HTLV-1-infected T-cell lines, we treated the cells with 50 µM AG490 for 24 h and performed EMSA (Figure ...HTLV-1-infected T-cell ...HTLV-1-infected T-cell ...
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Mechanisms employed by retroviruses to exploit host factors for translational control of a complicated proteome
... monkey virus (MPMV), human foamy virus (HFV), retic- uloendotheliosis virus strain A (REV-A), human T-cell leukemia virus type 1 (HTLV-1), feline ...
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In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor.
... Transcriptional activation of homologous viral long terminal repeats by the human immunodeficiency virus type 1 or the human T-cell leukemia virus type 1 tat proteins occurs in the absen[r] ...
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Replication and Pathogenicity of Primer Binding Site Mutants of SL3-3 Murine Leukemia Viruses
... host cell are annealed to the primer binding site (PBS) ...host cell tRNA population, and different viruses utilize different tRNA mole- cules as primers for reverse ...Murine leukemia viruses (MLV) ...
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Multidisciplinary insight into clonal expansion of HTLV-1–infected cells in adult T-cell leukemia via modeling by deterministic finite automata coupled with high-throughput sequencing
... Adult T-cell leukemia (ATL) is a life-threatening malig- nancy that manifests with very poor prognosis [11, ...with human T-cell leukemia virus type-1 (HTLV-1), ...
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HTLV 1 infection of myeloid cells: from transmission to immune alterations
... HTLV-1: Human T-cell leukemia virus type 1; ATLL: adult T-cell leukemia/lym- phoma; HAM/TSP: HTLV-1-associated myelopathy/tropical spastic paraparesis; ACs: ...
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