Human urine-derived stem cell
Hypoxic preconditioning of human urine-derived stem cell-laden small intestinal submucosa enhances wound healing potential
... fresh urine was collected from each ...in cell culture medium comprised of 50% Keratinocyte Serum-Free Medium (KSFM, Gibco, USA), ...after cell seeding and the non- adherent cells were ...
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Original Article The transplantation of human urine stem cells combined with chondroitinase ABC promotes brain-derived neurotrophic factor and nerve growth factor following spinal cord injury in rats
... regeneration. Cell-based ther- apy has been considered to be effective in pro- moting myelin regeneration and the recovery of spinal function ...embryonic stem cells, bone mar- row stromal cells, ...
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Extracellular matrix derived from human urine-derived stem cells enhances the expansion, adhesion, spreading, and differentiation of human periodontal ligament stem cells
... We also used hPDLSCs grown on TCP covered in fi- bronectin, an abundant component in UECM, as a con- trol group. In the proliferation assay, cells cultured on UECM- and PECM-coated TCP had similar growth rates and grew ...
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Silver nanoparticles promote osteogenic differentiation of human urine-derived stem cells at noncytotoxic concentrations
... engineering, urine-derived stem cells are ideal seed cells and silver nanoparticles (AgNPs) are perfect antimicrobial ...on urine-derived stem cells, a study was conducted to ...
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Urine-derived cells for human cell therapy
... grain”-like urine stem cells were transdifferen- tiated into spindle-shaped skeletal cells on myogenic dif- ferentiation, with high levels of expression of skeletal muscle markers ...using stem cells ...
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Human urine derived stem cells in combination with polycaprolactone/gelatin nanofibrous membranes enhance wound healing by promoting angiogenesis
... USCs: Human urine-derived stem cells; PCL/GT: Polycaprolactone/gelatin; HUVECs: Human umbilical vein endothelial cells; ASCs: Adipose-derived mesenchymal stem cells; CMC: ...
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The challenges and promises of allogeneic mesenchymal stem cells for use as a cell-based therapy
... The effectiveness of genetically modified auto-MSCs has been reported in different disease models [50–52]. Similarly, the protective effect of allo-MSCs was im- proved by gene modification. de la Garza-Rodea et al. [53] ...
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Fibroblast growth factor-2 stimulates proliferation of human adipose-derived stem cells via Src activation
... of human embryonic stem cells (hESCs) and oncogenesis of tumors [39], whereas FGF signaling is important in early vertebrate development through the Ras/MAPK pathway, PLCγ/Ca ...
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The potential and limitations of induced pluripotent stem cells to achieve wound healing
... multiple cell types and ...therapies. Stem cell therapy is emerging as a potential treatment for chronic wounds, and adult-derived stem cells are currently employed in several ...
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PubMedCentral-PMC5831028.pdf
... (Figure 4B). To test the utility of this dataset to potentially inform chemically mediated differentiation strategies, we compared it with two previously published datasets from hPSC-derived neurons. First, we ...
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Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34+ cells using the auto-erasable Sendai virus vector
... 2000, and 4000 cells/well) onto iMatrix-511-coated 6- well plates containing StemFit AK02N medium. No more hematopoietic cytokines were needed beyond day 0. After seeding, some adherent cells showed ini- tial ...
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Therapeutic applications of adipose cell-free derivatives: a review
... require cell separation and in vitro cultivation and can be quickly prepared in the operating room or simple laboratory, significantly reducing the risk of biological contamin- ...medium derived from ...
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Large animal models for stem cell therapy
... of cell- based ...of stem cell actions and preclinical evidence for safety and therapeutic effi ...potential stem cell-based products that can be used for regenerative medicine, ...
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Developmental cues for the maturation of metabolic, electrophysiological and calcium handling properties of human pluripotent stem cell-derived cardiomyocytes
... increases by over three-fold at term. Thyroid hormone has been shown to exert effects during different stages of cardiac development; it mediates a myosin heavy chain isoform switch from predominantly β in the fetal ...
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The advancement of human pluripotent stem cell derived therapies into the clinic
... embryonic stem cells (hESCs) were first reported in 1998 by Dr Jamie Thomson ’ s group, and their reprogrammed cousins, human induced pluripotent stem cells (hiPSCs), were described in 2007 (Yu et ...
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Extracellular vesicles derived from human ES-MSCs protect retinal ganglion cells and preserve retinal function in a rodent model of optic nerve injury
... 80% cell confluency (days 3–4). The EVs were extracted from the human ES-MSC culture medium using ultracentrifugation; all the centrifugation processes performed at 4 ...
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Systems biology discoveries using non-human primate pluripotent stem and germ cells: novel gene and genomic imprinting interactions as well as unique expression patterns
... PSCs derived from the adult human testis ...germ cell factors could infl uence their ability to become pluripotent (for example, including expression of genes associated with ...In human ...
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Original Article Comparison of different conditions for culturing of mesenchymal stem cells from human umbilical cord Wharton’s jelly
... four cell groups. Proliferative activities, cell cycle analysis, flow cytometric analysis, apoptosis anal- ysis, and the differentiation potential of these four cell populations were ...
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Polyethylene glycol in spinal cord injury repair: a critical review
... Abstract: Polyethylene glycol (PEG) is a synthetic biocompatible polymer with many useful properties for developing therapeutics to treat spinal cord injury. Direct application of PEG as a fusogen to the injury site can ...
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Scalable Generation of Mesenchymal Stem Cells from Human Embryonic Stem Cells in 3D
... pluripotent stem cells (iPSC) are unlimited and stable sources with the potential to differentiate into any cell type in the ...previously derived from hESC via co-culturing with mouse OP9 cells, ...
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