Hydroxyethyl starch 130/0.4
Interactions between the volume effects of hydroxyethyl starch 130/0 4 and Ringer´s acetate
... Methods: Ten male volunteers with a mean age of 22 years underwent three infusion experiments, on separate days and in random order. The experiments included 10 mL/kg of 6% hydroxyethyl starch ...
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Clinical Utility of Intra-Operative 6% Hydroxyethyl Starch (130 / 0.4) Supplementation in Hypoxemic Femur Injury Patients: A Preliminary Report of Twenty Cases
... Demographic characteristics, new injury severity score, time lapse from injury to admission and injury to sur- gery, duration of surgery, time of reaming and anesthe- sia time were similar in both groups (Table 1). ...
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A Comparative Retrospective Analysis of Mortality, Renal Dysfunction, and Incidence of Bleeding in Patients Receiving Hydroxyethyl Starch 130/0 4 (HES 130/0 4) or Albumin
... trials, hydroxyethyl starch ...all hydroxyethyl starch products continue including coagulation abnormali- ties, acute kidney injury/renal failure, and refractory pruritus which are generally ...
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Early fluid resuscitation with hydroxyethyl starch 130/0 4 (6%) in severe burn injury: a randomized, controlled, double blind clinical trial
... the first few hours after trauma. The capillary leak is be- lieved to resolve within 8 to 24 hours after trauma, but data vary [1,5]. In this critical situation of massive inflam- mation, hypovolemia, and large edema ...
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Efficacy and safety of 6% hydroxyethyl starch 130/0 4 (Voluven) for perioperative volume replacement in children undergoing cardiac surgery: a propensity matched analysis
... Human albumin (HA) and crystalloids remain first choices for CPB priming and volume replacement in the perioperative period of pediatric cardiac surgery [6]. Compared with crystalloids, the administration of HA in the ...
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The Volume Effect and Safety of 6% Hydroxyethyl Starch 130/0 4 in Patients Undergoing Major Elective Surgery: An Uncontrolled, Open Labeled, Multi Center Study
... Purpose: The primary aim of this study was to investigate volume effect and safety of up to 50 mL/kg BW 6% hy- droxyethyl starch (HES) 130/0.4 in adult and pediatric patients undergoing major elective ...
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Effects of hydroxyethyl starch 130/0.4 on the kidney tissue of rats with ureteral obstruction
... At the end of the 3-week period, anesthesia was induced using 100 mg/kg ketamine intraperitoneally, and 20 mL/kg HES 130/0.4 was then administered over 15 minutes intra- venously through the tail vein. After the ...
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Hydroxyethyl starch 130/0.4 and sodium chloride injection as adjunctive therapy in patients with cerebral hypoperfusion
... Because of the lack of reliable clinical data, the effect of volume therapy (HES 130/0.4) on cerebral hypoper- fusion due to severe ICA/MCA stenosis or occlusion is largely unsettled. In this trial, three types of ...
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Effects of synthetic colloids on oxidative stress and inflammatory response in hemorrhagic shock: comparison of hydroxyethyl starch 130/0 4, hydroxyethyl starch 200/0 5, and succinylated gelatin
... coagulation impairment [21,24] and bleeding events [25] compared to HES 130. Extensive cross-talk is observed between inflammation and hemostasis [26]. Vancine et al . demonstrated that factor VIII deficiency is ...
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Effect of 6% Hydroxyethyl Starch 130/0 4 as a Priming Solution on Coagulation and Inflammation Following Complex Heart Surgery
... Purpose: Prolonged duration of cardiopulmonary bypass aggravates the degree of inflammation and coagulopathy. We investigated the influence of 6% hydroxyeth- yl starch (HES) 130/0.4 on coagulation and ...
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Comparing the effect of hydroxyethyl starch 130/0 4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S Scandinavian Starch for Severe Sepsis/Septic Shock trial): Study protocol, design and rationale for a double blinded, randomised clinical trial
... weight hydroxyethyl starch (HES) may cause acute kid- ney failure (AKF) in patients with severe sepsis as observed in a recent meta-analysis ...- hydroxyethyl groups per glucose), but found divergent ...
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Update on transfusion solutions during surgery: review of hydroxyethyl starches 130/0.4
... substitution. Hydroxyethyl starch 130/0.4 (mean molecular weight, 130 kd; degree of substitution, ...newer starch-based plasma volume expanders has been driven by the need to improve ...
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Extracellular Fluid Accumulation Predicts Fluid Responsiveness after Hydroxyethyl Starch 70/0 5 Bolus Infusion during Major Abdominal Surgery
... Contrary to our expectations, pre-bolus SVV did not predict fluid responsiveness after HES bolus infusion. The threshold of SVV for fluid responsiveness defined as an increase in cardiac output (e.g., 12%) was reported ...
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HES 130/0 4 impairs haemostasis and stimulates pro inflammatory blood platelet function
... Hydroxyethyl starch (HES) solutions are widely used for vol- ume replacement therapy in anaesthesiology and intensive care medicine despite a lack of clinical superiority over crystal- loid solutions in ...
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Effects of synthetic colloid and crystalloid solutions on hemorheology in vitro and in hemorrhagic shock
... by forming dextran bridges between the cells [8,9]. Hydroxyethyl starch (HES) 450/0.7 infusion elevated blood viscosity and erythrocyte aggregation while de- creasing the erythrocyte deformability [6]. ...
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Hydroxyethyl Starch- Friend or Foe?
... Reductions in MW and MS have led to products with shorter half-lives, improved pharmacokinetic and pharmacodynamic properties, and fewer side effects [17]. Two third-generation starches, one based on waxy maize and other ...
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Effect of restrictive fluid therapy with hydroxyethyl starch during esophagectomy on postoperative outcomes: a retrospective cohort study
... effective volume expander than crystalloids, could be a good choice for proper intravenous fluid therapy during esophageal surgery [18]. Our study also indicates that the increased use of HES during surgery was ...
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Hydroxyethyl starch 6%, 130/0.4 vs. a balanced crystalloid solution in cardiopulmonary bypass priming: a randomized, prospective study
... A prospective and randomized study has been carried out. The study was approved by the “Medicana Inter- national Ankara Hospital Ethics Committee” and written informed consent was taken from every patient. The only ...
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Adverse effects of hydroxyethyl starch (HES 130/0 4) on intestinal barrier integrity and metabolic function are abrogated by supplementation with Albumin
... The application of HES for volume resuscitation is con- troversially discussed and clinical studies have suggested adverse effects of HES substitution, leading to increased patient mortality [1, 4, 25]. The ...
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6% Hydroxyethyl starch (HES 130/0 4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice
... animals were randomized to treatment groups, and the investigators were blinded to these groups. An animal group size of eight mice was analyzed for each condition. Pulmonary inflammation induced by inhalation of lipo- ...
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