IFN-γ/IL-4
Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN γ, IL 4, IL 5 and IL 10 with age
... tralising IL-10 using samples from a subgroup of the par- ticipants who had provided enough blood to allow additional assays (n = 17, age range 6–17 years, mean infection intensity range 0–111 eggs/10 ml ...
11
IFN-γ, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13
... antagonize IL-13-induced STAT6 activity in air- way epithelial cells, an effect that is time- and dose- dependent ...of IFN-γ on IL-4 sig- nalling has been more extensively studied and ...
16
IL 1 Receptor Type II Production Is Upregulated by IL 4 and IL 13, and Downregulated by IFN γ in Mouse Gingival Epithelial Cells
... multiple IL-4/IL-l3-inducible genes, including IL-1Ra [56], Fc epsilon receptor II [57], and IL-4 receptor ...[58]. IL-4 and IL-13 failed to induce ...
11
IFN-γ +874 and IL-4 -590 Polymorphisms and Asthma Susceptibility in North West of Iran
... of IFN-γ +874 A/T, and IL-4 - 590 C/T polymorphisms in asthmatic patients and controls in West Azerbaijani population (North-West of ...of IL-10 -1082 A/G, IFN-γ +874 A/T ...
6
Evaluation of IL-4, IL-17, and IFN-γ Levels in PatientsWith Breast Cancer
... All samples were stored at -80°C. To obtain a homogenous tissue solution, tissue samples were homogenized by a Homogenizer (Topsonic, Iran) for 15 minutes. The resultant homogeneous solutions were then centrifuged for 15 ...
5
Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study
... cytokines IL-2, IL-4 and IL-6. Interestingly, IL-6 is part of a cytokine family with well-defined neurological impacts ...as IL-6 to pregnancy complications and neurological ...
11
Deficiency of Vitamin D in HIV Infected Patients and Its Effect on Some of the Immunological Parameters
... low IFN- γ (mean < ...average IFN- γ value that was measured was above the upper referent limit (mean > 56 ...the IL-4 level and the IFN- γ ...
7
Original Article Effect of rTsP53 on the M1/M2 activation of bone-marrow derived macrophage in vitro
... (IFN-γ, IL-6 and TNF-α) level decreased in the culture medium supernatant of BMDM co-incubated with ...and IL-13) and regulatory cyto- kines in the culture medium ...with IFN-γ, ...
16
Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD
... and IL-1 that protect against tissue ...feron- γ (IFN- γ ), a "master" cytokine that orchestrates the coordinated induction and production of the "killing" phase ...as ...
12
Human limbal fibroblast-like stem cells induce immune-tolerance in autoreactive T lymphocytes from female patients with Hashimoto’s thyroiditis
... and IL-6, and considerably increase PDL-1 and PDL-2 expression at the protein ...in IFN-γ and IL-17A levels as observed in female HT-derived T ...
14
Naturally acquired cellular immune response against Plasmodium vivax merozoite surface protein 1 paralog antigen
... To evaluate the response of helper T cells upon PvMSP1P- 19 stimulation, the cell phenotypes were analysed by flow cytometry (BD FACScanto II; Becton Dickinson, Oxford, UK). Th1 or Th2 cells were defined by staining with ...
9
The IL 23/IL 17 axis in inflammation
... not IFN-γ and ...blocking IL-23 or its downstream factors IL-17 and IL-6, but not the IL-12/ IFN-γ pathways, can significantly suppress disease development in ...
6
Cytokine patterns in nasal secretion of non-atopic patients distinguish between chronic rhinosinusitis with or without nasal polys
... CRSsNP. IL-5, IL-10, IL-12, IL-17, and IFN-γ represent a disequilibrium of T cells in NP, and ECP, tryptase, G-CSF, MCP-1, MIP-1α, and MIP-1β depict the activation of various ...
9
Simvastatin increases cell viability and suppresses the expression of cytokines and vascular endothelial growth factor in inflamed human dental pulp stem cells in vitro
... Quantitative real-time PCR (qPCR) was performed to quantify the expression of interleukin (IL)-1, IL-4, IL-6, IL-1β, interferon-gamma (IFN-γ) and tumor necrosis fac- ...
9
Temporal regulation of natural killer T cell interferon gamma responses by β-catenin-dependent and -independent Wnt signaling
... staining was performed on leukocytes using the Cytofix/Cytoperm kit (BD Biosciences) according to the manufacturer’s instruc- tions. Fc receptor binding was blocked with anti-mouse CD16/32 (2.4G2; BD Pharmingen) before ...
13
Assessment of Immunological Changes in Workers Occupationally Exposed to Low Levels of Ionizing Radiation
... The current observations did not reveal statistically significant differences in serum TNF-α and IFN-γ concentrations in group 2 than in control group. Different studies indicate that ionizing radiation ...
16
The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen
... secrete IFN-γ or Th2 cells that secrete IL-4, IL-5, and IL-13 ...of IL-12 by DC1s favors the develop- ment of Th1 cells ...and IFN-γ, which are potent ...
10
Imbalanced shift of cytokine expression between T helper 1 and T helper 2 (Th1/Th2) in intestinal mucosa of patients with post-infectious irritable bowel syndrome
... secrete IFN-γ, IL-12, IL-2, and tumor necrosis factor-α (TNF-α), and mediate cellular immunity, while Th2 cells play a key role in promoting Th1 differentiation and the Th1 ...produce ...
6
Anti-inflammatory effect of hesperidin enhances chondrogenesis of human mesenchymal stem cells for cartilage tissue repair
... of IFN- γ , IL-2, IL-4 and IL-10, and enhances chondrogenesis of ...of IFN- γ , IL-2, IL-4 and IL-10 in the ...
8
Pathogen imposed skewing of mouse chemokine and cytokine expression at the infected tissue site
... Both IL-4– and IFN-γ–produc- ing effector T cells homed to inflamed OVA/CFA-immunized dermis, but only IL-4–producing cells homed to ...
12