IL-1 Family cytokine
Interleukin-1 Family Cytokines as Mucosal Vaccine Adjuvants for Induction of Protective Immunity against Influenza Virus
... of 1 g of an IL-1 family cytokine for four consecutive days has been shown to induce asthma-like symptoms, including airway hyperresponsiveness and goblet cell hyperplasia in the ...
10
Evaluating the levels of interleukin-1 family cytokines in sporadic amyotrophic lateral sclerosis
... active cytokine because inhibition efficiency depends both on the kinetics of association and dissociation between the two molecules, and on the actual concentration of IL-18 and IL-18BP in serum ...
7
Divergent roles for the IL 1 family in gastrointestinal homeostasis and inflammation
... regard, IL-37 may perform a similar function to IL-1Ra and IL-18BP, the expression of which is also up-regulated during active ...of IL-37 exist in humans, IL- 37a-e, with IL-37b ...
23
Extracellular Neutrophil Proteases Are Efficient Regulators of IL 1, IL 33, and IL 36 Cytokine Activity but Poor Effectors of Microbial Killing
... their cytokine-processing function predominating upon libera- tion into the extracellular ...extended IL-1 family were activated or inactivated by neutrophil granule proteases, our ...
15
Evaluating the role of IL-11, a novel cytokine in the IL-6 family, in a mouse model of spinal cord injury
... Mice were overdosed with isoflurane. Each animal was then perfused intracardially with 30 mL of RNase-free Ringer’s solution at 4°C. The spinal column was then dissected out of the mouse and immediately placed in ...
12
The Correlation between Increased Serum Concentrations of Interleukin 6 Family Cytokines and Disease Activity in Rheumatoid Arthritis Patients
... (IL)-6 family cytokines are elevated in patients with rheuma- toid arthritis (RA) and to investigate the relationship between IL-6 family cytokine levels and disease activity in RA ...
8
Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family
... p40, IL-27p28, and EBI3 was detected by SYBR Green-based real-time ...for 1 min, 57°C for 30 sec, for 40 cycles, followed by a melting point determination or dissociation ...
10
Oestrogen receptor negative breast cancers exhibit high cytokine content
... the cytokine family (IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL- 10, IL-12 [p70], IL-13, IL-17, granulocyte colony-stimulating ...
11
Lactobacillus acidophilus Induces Cytokine and Chemokine Production via NF-κB and p38 Mitogen-Activated Protein Kinase Signaling Pathways in Intestinal Epithelial Cells
... IEC sense bacteria through expression of conserved pattern recognition receptors (PRRs), such as the Toll-like receptors (TLRs) (21, 26). Some studies have shown that TLR2 and TLR4 were constitutively expressed both in ...
6
Neonatal alveolar macrophages upregulate cytokine gene transcription via p38 MAPK signaling but fail to secrete cytokines in response to Respiratory Syncytial Virus
... of IL-1 β protein during RSV infection Freshly isolated AMΦs from adult (n=8) or neonatal (n=8) sheep were stimulated in vitro with BRSV, following pre-incubation with p38 MAPK inhibitor, SB203580, or ...
75
Changes in Follicular Helper T Cells in Idiopathic Thrombocytopenic Purpura Patients
... Chronic ITP is an immune-mediated disorder characterized by a transient decrease in or persistently decreased platelet count caused by the platelet de- struction, and the platelet antibody–mediated platelet destruction ...
10
Infection with Theiler's Murine Encephalomyelitis Virus Directly Induces Proinflammatory Cytokines in Primary Astrocytes via NF-κB Activation: Potential Role for the Initiation of Demyelinating Disease
... induces cytokine gene expression similar to TMEV in astro- cytes (data not ...TMEV-induced cytokine expression can be ...this cytokine produced after various infections is known to induce various ...
10
Neuroinflammation induces glial aromatase expression in the uninjured songbird brain
... cut on a cryostat at 40 μm after being gel embedded and stored in cryoprotectant at -20C until use. Follow- ing standard immunohistochemistry protocols, free- floating sections were washed 6 × 10 min in 0.1 MPB, then ...
11
Effect of gold sodium thiomalate and its thiomalate component on the in vitro expression of endothelial cell adhesion molecules
... inhibited cytokine (TNF, IL-1, IL-4)-stimulated expression of vascular cell adhesion molecule-1 and E-selectin but not intercellular adhesion molecule-1 on endothelial ...
9
Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri
... inflammatory cytokine interleukin 1 (IL-1), but not IL-6 or tumor necrosis factor alpha (TNF ...of IL-1 from prestimulated peritoneal macrophages, before the cell's ...
6
The IL-12 family and dendritic cells : key regulators of immunity and immunological tolerance
... cealla cytokine singil a thairgeadh agus is feídir réimse leathan feidhmiúcháin a bheith ...ghrúpa IL-12. Tá sé déanta suas de cheithre bhaill; IL-12 agus IL-23, is iad sin na cealla ...
167
A regulatory role for IL 4 in differential inflammatory responses in the lung following infection of mice primed with Th1 or Th2 inducing pertussis vaccines
... proinflammatory cytokine production in the brain; IL-1 protein and mRNA expression were detected in the hippocampi and hypothalami of immunized or infected mice ...stimulate IL-1 and ...
8
Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN γ, IL 4, IL 5 and IL 10 with age
... and cytokine level being significant for IL-4 and IL-5 cytokines believed to be important in protection against re-infection with ...as IL-10 which has pre- viously been associated with ...of ...
11
Alterations of anti-inflammatory lipids in plasma from women with chronic widespread pain - a case control study
... and IL-1β were analysed with the commercial High Sensitivity Human Cytokine Magnetic Bead Panel Immunoassay (MILLIPLEX® MAP for Luminex® xMAP1 Technology, EMD Millipore, Missouri, ...used. IL-6, ...
9
Human Metapneumovirus Induces a Profile of Lung Cytokines Distinct from That of Respiratory Syncytial Virus
... 0.5, 1, 2, 3, 5, 8, and 10 days postinfection, bronchoalveolar lavage (BAL) fluid was collected by washing the lungs two times with 1 ml of minimal essential medium (Gibco) supplemented with 2% bo- vine ...
6