Independent mechanisms
Antibody-dependent and -independent mechanisms of inflammatory arthritis
... Inflammatory arthritis is not a single disease. Broadly, inflammatory arthritis may be divided into conditions focused on the synovium and those that also affect the entheses, the insertion zones of ten- dons, ligaments, ...
16
Stat3 protects against Fas induced liver injury by redox dependent and independent mechanisms
... Signal transducer and activator of transcription-3 (Stat3) is one of the most important molecules involved in the initiation of liver development and regeneration. In order to investigate the hepato- protective effects ...
11
Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms
... methylation- independent mechanisms through which Dot1 dere- presses Sir-repressed genes, we investigated whether Dot1 binding affected anchoring of the silenced telomere to the nuclear ...
14
Sodium Nitroprusside inhibits HEK293 Cell Growth by cGMP Dependent and Independent Mechanisms
... Several cGMP independent mechanisms have been reported for SNP action [28]-[31], among which the for- mation of S-nitrosoglutathione induces apoptosis [20]. The present observation that GSSG level increased ...
10
TGFβ signals regulate axonal development through distinct Smad independent mechanisms
... Proper nerve connections form when growing axons terminate at the correct postsynaptic target. Here I show that Transforming growth factor beta (TGF β ) signals regulate axon growth. In most contexts, TGF β signals are ...
11
DCYTB is a predictor of outcome in breast cancer that functions via iron independent mechanisms
... We therefore sought to understand in greater depth the nature of the association of DCYTB with breast can- cer, and to explore the role of DCYTB in the breast. We first expanded our assessment of the ability of DCYTB to ...
18
Twisted gastrulation enhances BMP signaling through chordin dependent and independent mechanisms
... Tsg decreases steady-state levels of Chordin To test the effect of Tsg on Chordin efficacy in our system, and the dependence of the effect on cleavage by Tld at either site, we performed[r] ...
9
Zic2 promotes axonal divergence at the optic chiasm midline by EphB1 dependent and independent mechanisms
... the mechanisms of axonal navigation has revealed that combinations of transcription factors expressed in neuronal subpopulations control diverse trajectories to specific targets (Jessell, 2000; Shirasaki and ...
9
COP9 signalosome subunits protect Capicua from MAPK dependent and independent mechanisms of degradation
... Our analysis confirms that CSN1b, which had not previously been studied in vivo, shares functions with CSN4, CSN5 and CSN8 in eye development (Cope et al., 2002; Suh et al., 2002), Hedgehog signaling (Wu et al., 2011) ...
10
Species-specific modifications of mandible shape reveal independent mechanisms for growth and initiation of the coronoid
... How the variability between species is developmentally patterned is currently unknown. In the mouse, the basic shape of the dentary, including the proximal coronoid, condylar and angular processes, is established before ...
14
SGLT2 inhibition reprograms systemic metabolism via FGF21-dependent and -independent mechanisms
... Interestingly, we now report that FGF21 is not required for either CANA-mediated improvement in glu- cose tolerance or induction of a broad fasting-like catabolic transcriptional program. At a whole-body level, CANA ...
18
DDB1 Stimulates Viral Transcription of Hepatitis B Virus via HBx-Independent Mechanisms
... Northern blot analysis showed that DDB1 elevated the levels of viral transcripts in both WT replicontransfected cells and X-null replicon-transfected cells, indicating a direct effect of[r] ...
10
Two independent mechanisms for motion in depth perception : evidence from individual differences
... brain mechanisms responsible for depth perception from binocular disparity (Cumming and DeAngelis, 2001; Howard, 2002; Howard and Rogers, 2002), understanding how binocular vision is used to perceive ...
8
An improved method to study NK-independent mechanisms of MTLn3 breast cancer lung metastasis
... Eradication of the NK cells by pre-treating the rats with an NK cell depleting antibody resulted in the formation of more than 130 lung metastases within four weeks after injection of th[r] ...
9
PPAR[gamma]-independent mechanisms of Src kinase activation and EGFR transactivation in response to thiazolidinediones
... 1.3. Mechanisms of MAPK activation in the rat liver epithelial cells GN4 by PPAR ...second, independent pathway was shown to be involved in increased Erk phosphorylation following nafenopin and ciglitazone ...
145
PRH represses transcription in hematopoietic cells by at least two independent mechanisms
... the promoter, PRH might repress transcription via protein- protein interactions with TBP and/or via homeodomain-inde- pendent mechanisms. To delineate the regions of PRH that function as repression domains, a ...
11
B cells contribute to MS pathogenesis through antibody-dependent and antibody-independent mechanisms
... and memory B cells, but not stem cells or plasmablasts) – has made it possible to discern whether B cells themselves or their antibody products contribute to MS pathogenesis. In various studies, RRMS patients receiving ...
7
Role of vitamin D dependent and vitamin D independent mechanisms in absorption of food calcium
... We measured net calcium absorption and the calcium content of the digestive glands secretions in people with widely different serum concentrations of 1,25 dihydroxy vitamin D (hereafter referred to a 1,25-D). Patients ...
8
Diffusion Controlled Oxidative Degradation of Un stabilised Polyethylene
... The experimental results above show two independent mechanisms of degradation: oxidation of the surface layer by formation of carbonyls as revealed by FTIR and a continuous progress of t[r] ...
7
Mechanisms of Rad52-Independent Spontaneous and UV-Induced Mitotic Recombination in Saccharomyces cerevisiae
... Even in Saccharomyces, there are several Rad52- independent mechanisms of double-strand break (DSB) repair. Single-strand annealing becomes Rad52 inde- pendent when homologous regions are several kilobases ...
13