induced pluripotent stem cells (iPS cell) (iPSC)
Generation of induced pluripotent stem cells from large domestic animals
... iPSCs: Induced pluripotent stem cells; OSKM: Oct4, Sox2, KFL4, and c-Myc; biPSCs: Bovine induced pluripotent stem cells; miPSCs: Mouse induced ...
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Induced pluripotent stem cells in infections
... of induced pluripotent stem cells came into ...effector cells as they contain plethora of cytotoxic mediators such as ECP, EDN, MBP, EPO and many more ...
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Induced Pluripotent Stem Cells: History, Properties and Potential Applications
... of induced pluripotent stem cells (iPSCs) has been met with much enthusiasm and hailed as a breakthrough discovery by the scientific and research communities amidst the divisive and ongoing ...
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Role of tumor suppressor genes in the cancer-associated reprogramming of human induced pluripotent stem cells
... their pluripotent characteristics, human induced pluripotent stem cells (iPSCs) possess great potential for therapeutic application and for the study of degenerative ...These ...
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Mouse induced pluripotent stem cells
... reprogrammed cells (Brambrink et ...identify cells at specific intermediate stages in the reprogram- ming process (by their specific gene marker expression) should prove useful in further deciphering the ...
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Induced pluripotent stem cells in medicine and biology
... In 2007, the proof of concept of the therapeutic use of iPSCs was reported for the mouse model of sickle-cell anemia, a genetic blood disorder caused by a defect in the β-globin gene (Hanna et al., 2007). Gene correction ...
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Induced pluripotent stem cells: advances to applications
... way, stem cell-based regenerative medicine is expected to drive the evolution of medical sciences from palliation, which mitigates symptoms, to curative therapy aimed at treating the root cause of degenerative and ...
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Induced pluripotent stem cells: An update
... the cells were tolerated by the immune system ...took cells from a chimera that had been grown from iPSC clones and a mouse embryo and transplanted into syngenic ...
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Pluripotency of induced pluripotent stem cells
... somatic cells from various mammalian species can be reprogrammed into induced pluripotent stem (iPS) cells by the ectopic expression of four transcription factors that are highly ...
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Disruption of histamine/H1R signaling pathway represses cardiac differentiation and maturation of human induced pluripotent stem cells
... The in vitro cardiac differentiation from PSCs is simi- lar to heart development involving the primitive streak formation, the specification of the lateral mesoderm, and the generation of cardiac progenitor cells ...
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Biomedical Applications of Induced Pluripotent Stem Cells
... iPS cells from a child afflicted with a genetic spinal muscular ...These cells were able to maintain the disease genotype, and capable of differentiating into motor neurons that revealed specific defects in ...
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Understanding Megakaryopoiesis And Thrombopoiesis Using Human Stem Cells Models
... Human stem cell models (CD34+ hematopoietic progenitors, embryonic stem cells and induced pluripotent stem cells (iPSCs)) are powerful tools for the study of ...
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Transplantation of induced pluripotent stem cell-derived mesenchymal stem cells improved erectile dysfunction induced by cavernous nerve injury
... Induced pluripotent stem cells (iPSC) are pluripotent stem cells generated by reprogramming somatic cells ...(induced pluripotent stem ...
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Directly induced human Schwann cell precursors as a valuable source of Schwann cells
... iSCPs: Induced-Schwann cell precursors; iSCs: iSCP-derived Schwann cells; iPSC: Induced pluripotent stem cells; hESCs: Human embryonic stem cells; NCSCs: Neural ...
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Advances in Regenerative Medicine: From Stem Cells to Organoids
... used stem cells to develop substitute tissue/organs “ex vivo” with various degree of success, which the ultimate goal is to be trans- planted to replace a damaged organ ...various stem cells, ...
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Therapeutic use of stem cells for cardiovascular disease
... of cells have been explored, each with their own benefits and ...limitations. Induced pluripotent stem cells possess an embryonic-like state and therefore have a high proliferative ...
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Mesenchymal stem cell-based cell-free strategies: safe and effective treatments for liver injury
... multipotent cells that are able to proliferate, self- renew, and differentiate into various somatic cells in vitro, and they have attracted much attention for re- storing tissue function in vivo with little ...
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A SY Stematic approach towards understanding stem cell biology
... various stem cell research ...how stem cells make ‘ decisions ’ during early development and how stem cells function in the ...embryonic stem cells (ESCs), induced ...
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Stem cells: a model for screening, discovery and development of drugs
... conclusion, stem cells (both normal and cancerous) are a valuable tool in the drug discovery ...tumorigenic stem cell behavior (Figure ...embryonic stem cells are limited due to ethical ...
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Ex Vivo Gene Therapy for Lysosomal Storage Disease Using Ipsc-Derived Neural Stem Cells
... Induced pluripotent stem cells are promising candidates for treating many diseases in the ...patient cells because of the cross-correction ...deficient cells (Fratantoni et ...
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