Inhaled corticosteroid therapy
Effect of long term inhaled corticosteroid therapy on adrenal suppression, growth and bone health in children with asthma
... Background: Inhaled corticosteroids (ICS) are the most effective treatment for children with persistent ...term inhaled corticosteroid therapy (ICS) on adrenal function, growth and bone health ...
6
Extrafine inhaled corticosteroid therapy in the control of asthma
... extrafine inhaled corticos- teroid particle sizes may achieve sufficient deposition in the peripheral ...extrafine inhaled corticosteroids on inflammation, ie, on dysfunction in both the central and distal ...
12
Is low dose inhaled corticosteroid therapy as effective for inflammation and remodeling in asthma? A randomized, parallel group study
... study inhaled FP significantly reduced mRNA expression of the pro-inflammatory cytokines GM-CSF and TNF- a ...of inhaled budesonide (800 μg twice daily) in comparison to placebo [48], given the lack of ...
11
Adrenal suppression: A practical guide to the screening and management of this under-recognized complication of inhaled corticosteroid therapy
... ICS therapy on the HPA axis, it is important to remember that effective anti- inflammatory therapy is essential for the treatment of asthma, that ICSs are the most effective anti-inflamma- tory agents ...
12
Short-term effect of a smart nebulizing device on adherence to inhaled corticosteroid therapy in Asthma Predictive Index-positive wheezing children
... Asthma is the most prevalent chronic disease in children, and the majority of asthma or wheezing starts before the age of 5 years. While the management of these children is complicated, nebulization of steroid or ...
8
Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy
... ICS: Inhaled Corticosteroids; mRNA: Messenger RNA; messenger Ribonucleic Acid; NR3C1: Nuclear Receptor Subfamily 3 Group C Member 1; ORMDL3: ORMDL Sphingolipid Biosynthesis Regulator 3; SGK1: ...
8
Inhaled Corticosteroid Therapy for Asthma in Preschool Children: Growth Issues
... Several conclusions appear well-supported by studies of ICS in school-aged prepubertal children. First, ICS used in small dosages present no signifi- cant risk for systemic adverse effects. When ICS are used at higher ...
10
Overt Glucocorticoid Excess Due to Inhaled Corticosteroid Therapy
... are discontinued.’6 Occasionally, however, fur- then depression in serum cortisol levels following initiation of tniamcinolone acetonide may ur’3 Although tniamcinolone acetonide use in [r] ...
6
Randomised trial of once-daily vilanterol in children with asthma on inhaled corticosteroid therapy
... Background: Inhaled corticosteroids (ICS) are effective maintenance treatments for childhood asthma; however, many children remain ...an inhaled long-acting beta-2 agonist which, in combination with the ICS ...
11
Inhaled corticosteroid treatment for 6 months was not sufficient to normalize phagocytosis in asthmatic children
... The internalization of particles by phagocytes occurs via receptors. When phagocytosis occurs via pattern- recognition receptors, the phagocyte recognizes directly conserved pattern molecular in the surface of the par- ...
12
Adjunctive corticosteroid therapy for inpatients with Mycoplasma pneumoniae pneumonia
... A total of 2718 patients with M. pneumoniae pneumo- nia were admitted to 690 hospitals from January 2010 to December 2013. Among them, 2390 patients were diagnosed by paired antibody titers, 213 by polymerase chain ...
10
A Double-Blind Trial of Corticosteroid Therapy in Status Asthmaticus
... The use of adrenocorticosteroids in treatment of status asthmaticus produced a more rapid re- covery from arterial hypoxemia than that noted in placebo patients treated identically but w[r] ...
9
Management of Pituitary-Adrenal Suppression Secondary to Corticosteroid Therapy
... High doses of exogenous steroids wifi suppress ACTH and adrenal secretion over the short term, but if the duration of therapy is brief (less than five days), the recovery of normal adren[r] ...
9
<p>Inhaled Corticosteroid Treatment Regimens and Health Outcomes in a UK COPD Population Study</p>
... triple therapy. 30 Several trials have compared triple therapy to LAMA-LABA but a meta-analysis in 2018 found only modest improvements in ef fi cacy against exacerbations from triple therapy, except ...
10
Effectiveness using higher inhaled corticosteroid dosage in patients with COPD by different blood eosinophilic counts
... drug therapy, these COPD patients were randomized to and pre- scribed one of the two treatment doses, which were higher dosage (HD) and medium dosage (MD) of ...
8
Changes to inhaled corticosteroid dose when initiating combination inhaler therapy in long-acting β agonist-naive patients with asthma : a retrospective database analysis
... combination therapy among patients with asthma treated in GP ...add-on therapy with a LABA or other controller ...ICS therapy before starting therapy with a combination inhaler, suggestive of ...
9
Sputum eosinophilia can predict responsiveness to inhaled corticosteroid treatment in patients with overlap syndrome of COPD and asthma
... of inhaled procaterol hydrochloride), arterial blood gas analysis, analysis of inflammatory cells in induced sputum, and the findings on chest ...with inhaled corticosteroid (ICS; 400 µ g/day of ...
7
A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy
... GC therapy. Assessment of BMD at baseline and after 1 year of GC therapy in adults who are expected to be on prednisone ≥5 mg/day (or equivalent) for over 3 months is also ...pharmacologic therapy ...
25
Addition of Theophylline or Increasing the Dose of Inhaled Corticosteroid in Symptomatic Asthma: A Meta Analysis of Randomized Controlled Trials
... Because most of the included studies provided insuffi- cient information, we were not able to make a meta-analy- sis regarding symptom scores, rescue medication and exac- erbation in the present study. However, all four ...
8
Corticosteroid-sparing therapy: practice patterns among uveitis specialists
... Though they do not receive the highest favorability ratings for effectiveness, the most commonly used and most preferred drugs are from the antimetabolite class. Respond- ents indicate that the long-used methotrexate is ...
8