innate and adaptive immunity
Role of innate and adaptive immunity in obesity associated metabolic disease
... The prevalence of obesity has increased dramatically over the past three decades and has contributed to the increasing prevalence of insulin resistance (IR) and type 2 diabetes (T2D) as well as cardio- vascular disease, ...
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Influenza Virus Evades Innate and Adaptive Immunity via the NS1 Protein
... to immunity against influenza virus ...Th1 immunity is crucial for viral ...of innate immunity via the inhibition of type I interferon (IFN) production in infected ...inhibits innate ...
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Wakayama symposium: interface between innate and adaptive immunity in dry eye disease
... how innate immune mechanisms act following a local insult, why some patients are particularly vulnerable, and why local inflammation fails to resolve in these ...from innate to adaptive ...
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Autophagy in Innate Recognition of Pathogens and Adaptive Immunity
... to innate recognition, autophagy can be used to fa- cilitate MHC class II presentation of endogenous intracellu- lar antigens as well as phagocytosed or endocytosed extra- cellular antigens to activate CD4 T ...in ...
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Investigation of coordination and order in transcription regulation of innate and adaptive immunity genes in type 1 diabetes
... the innate and the adaptive arms of immune system in disease ...the innate and adaptive immunity gene sets, or their co- expression network structures in cohorts at different disease ...
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Inactivated Influenza Vaccine That Provides Rapid, Innate Immune System Mediated Protection and Subsequent Long Term Adaptive Immunity
... induce innate immunity to provide imme- diate protection as well as subsequent adaptive immunity, includ- ing heterologous CD8 ⫹ T cell-mediated responses, has yet to be ...
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Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes
... University of Cincinnati, unpublished data, February, 2017). Our emphasis has been on T cells and Tregs in these studies, but since both CD137 and CD137 ligand are expressed on APCs, the innate immune system may ...
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Modulation of innate and adaptive immunity by Fasciola hepatica
... the innate immune system and play an important role in organ development, tissue turnover, and ...important innate defence mechanism involving the internalization of particles and infectious ...
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Plasmacytoid Dendritic Cells: Linking Innate and Adaptive Immunity
... pDCs also accumulate in the epidermis and papillary dermis of the skin of patients with cutaneous SLE, psoriasis vulgaris, and allergic contact dermatitis but not in patients with atopic dermatitis (45, 151). pDCs may ...
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Effects of cholera toxin on innate and adaptive immunity and its application as an immunomodulatory agent
... Abstract: Cholera toxin (CT) is a potent vaccine adjuvant when administered via parenteral, muco- sal, or transcutaneous routes. It also inhibits innate inflammatory responses induced by pathogen-de- rived ...
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Immunological outcomes of exercise in older adults
... Macrophages are another class of lymphocytes belonging to the innate immune system that serve four important roles. They (1) present antigen to memory (but not naïve) cells, produce both (2) cytokines and (3) ...
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Patole, Prashant (2006): Nucleic acid specific Toll-like receptors in lupus nephritis. Dissertation, LMU München: Medizinische Fakultät
... on innate and adaptive immunity, and the potential mechanisms involved have been discussed in a detailed review by Theofilopoulos AN et al (88) A crucial role of DCs has been identified in autoimmune ...
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The Fungal Quorum Sensing Molecule Farnesol Activates Innate Immune Cells but Suppresses Cellular Adaptive Immunity
... on innate immune cells known to be important for fungal clearance and protective ...influencing innate immune cells to promote inflammation and mitigating the Th1 response, which is essential for fungal ...
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Oncolytic viruses as immunotherapy: progress and remaining challenges
... OV therapy holds the promise that it may function as a cancer vaccine strategy. This is based on available data that indicate that DAMPs and TAAs released from the tumor cells lysed by the replicating OVs induce ...
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Toward a Cure: Does Host Immunity Play a Role?
... epigenetic immunity, however, needs to be further ...epigenetic immunity exerts its protective response against the patho- genic nucleic acid invasion versus cultivates symbiosis with the DNA of ...
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Evolution of RNA- and DNA-guided antivirus defense systems in prokaryotes and eukaryotes: common ancestry vs convergence
... (pAgo)-centered innate immunity and CRISPR-Cas adaptive immunity as well as diverse branches of RNA interference (RNAi) in ...The adaptive immunity function in eukaryotes is ...
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The great debate at “Immunotherapy Bridge 2018”, Naples, November 29th, 2018
... of adaptive versus innate immunity in the anti-cancer immune ...both innate and adaptive immune cells, immunothera- peutic strategies have primarily focused on stimulation of ...
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Tumor immunology and cancer immunotherapy: summary of the 2014 SITC primer
... including innate immunity, adaptive immunity, dendritic cells, adoptive T cell therapy, anti-tumor antibodies, cancer vaccines, immune checkpoint blockade, challenges to immunotherapy, ...
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The iSBTc/SITC primer on tumor immunology and biological therapy of cancer: a summary of the 2010 program
... topics: innate immunity and inflammation; an overview of adaptive immunity; dendritic cells; tumor microenvironment; regulatory immune cells; immune monitoring; cytokines in cancer ...
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Balance between innate versus adaptive immune system and the risk of dementia: a population-based cohort study
... Only few studies examined the interplay between the in- nate and adaptive immunity by studying levels of these blood cell-based ratios in dementia patients. Two cross-sectional studies showed that NLR and ...
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