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Innate intestinal immune responses

T bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function

T bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function

... responses are essential in mediating immunity against intestinal parasites, 17,18,38,39 and previous studies have shown that T-bet- deficient mice display an accelerated expulsion of Trichinella spiralis. 40 ...

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Nanoparticles induce dermal and intestinal innate immune system responses in zebrafish embryos

Nanoparticles induce dermal and intestinal innate immune system responses in zebrafish embryos

... adaptive immune system not yet being fully de- veloped in zebrafish larvae, 35 the innate immunity is their first defense against ...invaders. Immune responses triggered by NPs is suggested to ...

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Immunopathological properties of the Campylobacter jejuni flagellins and the adhesin CadF as assessed in a clinical murine infection model

Immunopathological properties of the Campylobacter jejuni flagellins and the adhesin CadF as assessed in a clinical murine infection model

... elicit innate and adaptive immune cell responses within the large intestines of infected ...in innate immune cell subsets, such as F4/80 + macrophages and mono- cytes in the colonic ...

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T bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function

T bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function

... PowerPoint Presentation Supplemental figure 1 Supplemental Figure 1 IFNγ production is reduced in NK and CD4+ T cells from T bet deficient mice, Related to Figure 1 Representative plots and percentage[.] ...

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Loss of intestinal sympathetic innervation elicits an innate immune driven colitis

Loss of intestinal sympathetic innervation elicits an innate immune driven colitis

... Here, we describe colitis upon sympathectomy only seen in Rag1 − / − mice since we confirmed in an earlier report that wild-type mice, C57Bl/6, do not develop col- itis upon sympathectomy (Willemze et al. 2018). This is ...

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Commensal Bacterial Communities Regulate Antiviral Immunity

Commensal Bacterial Communities Regulate Antiviral Immunity

... influence immune cell development, function and homeostatic regulation within the intestinal environment, leading to altered host susceptibility to infectious or inflammatory ...of intestinal ...

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Viral Induction of Central Nervous System Innate Immune Responses

Viral Induction of Central Nervous System Innate Immune Responses

... and intestinal epithelium, respec- tively ...of immune reac- tants in response to nonclassical MHC class I expression and other stimuli, suggesting that a resident brain cell may act in a similar manner ...

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Amelioration of intestinal and systemic sequelae of murine Campylobacter jejuni infection by probiotic VSL#3 treatment

Amelioration of intestinal and systemic sequelae of murine Campylobacter jejuni infection by probiotic VSL#3 treatment

... comparable intestinal loads, but co-colonization did not result in reduction of the pathogen ...ameliorated intestinal apoptosis and pro-inflammatory immune responses as indicated by lower ...

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Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases

Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases

... the immune responses occurred in the periph- ery through cytokines and chemokines, which alert the CNS through humoral and/or neurochemical ...the immune stimulations as well as the healthy people ...

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Innate immune responses in hepatitis B virus (HBV) infection

Innate immune responses in hepatitis B virus (HBV) infection

... in immune responses, due to their ability to process foreign antigens and present them to ef- fector ...antiviral immune response, due to their ability to secrete type 1 ...an immune ...

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Treatment Strategies for Reducing Damages to Lungs in Coronavirus and Other Lung Infections

Treatment Strategies for Reducing Damages to Lungs in Coronavirus and Other Lung Infections

... Kinetic differences are reflected in ample data. It generally takes 4-7 days to activate adaptive immunity and achieve detectable antibodies [15]. In infants infected with RSV virus, viral clearance is typically ...

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PubMedCentral-PMC5674984.pdf

PubMedCentral-PMC5674984.pdf

... Of interest are recent studies identifying the micro-biota as a mediator of diet-induced modulation of host cellular processes, likely through the generation of selective metabolites. We direct readers to a series of ...

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The early intestinal immune response in experimental neonatal ovine cryptosporidiosis is characterized by an increased frequency of perforin expressing NCR1+ NK cells and by NCR1− CD8+ cell recruitment

The early intestinal immune response in experimental neonatal ovine cryptosporidiosis is characterized by an increased frequency of perforin expressing NCR1+ NK cells and by NCR1− CD8+ cell recruitment

... governing innate immunity against intracellular parasites. The adaptive immune response is often required for complete control of infection ...adaptive immune response and further studies are needed ...

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In vitro or in vivo models, the next frontier for unraveling interactions between Malassezia spp. and hosts. How much do we know?

In vitro or in vivo models, the next frontier for unraveling interactions between Malassezia spp. and hosts. How much do we know?

... the immune response transcriptome [143] and the miRNAs involved in the regulation of the immune response [144] that can help to evaluate the host response to a specific ...

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Emerging roles of gut microbiota and the immune system in the development of the enteric nervous system

Emerging roles of gut microbiota and the immune system in the development of the enteric nervous system

... the innate immune system of the mucosa is the population of macrophages, which perform functions related to innate and adaptive immunity and are essential for the response of gut tissues to injury ...

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Review on Human Immune Response against Hepatitis B Virus (HBV) Infection

Review on Human Immune Response against Hepatitis B Virus (HBV) Infection

... host immune system creates opportunity for HBV DNA integration into the host ...an immune response against the virus-infected liver cells, although immune suppression appears to enhance replication ...

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Critical Role for the Adenosine Pathway in Controlling Simian Immunodeficiency Virus-Related Immune Activation and Inflammation in Gut Mucosal Tissues

Critical Role for the Adenosine Pathway in Controlling Simian Immunodeficiency Virus-Related Immune Activation and Inflammation in Gut Mucosal Tissues

... tumor immune evasion (41– ...inflammatory responses (3, 22, 49–51), we studied the changes in CD39 and CD73 expression on Tregs from the gut of SIV-infected nonhuman primates ...modulating immune ...

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GM-CSF and the role of myeloid regulatory cells in the pathogenesis and treatment of Crohn’s disease

GM-CSF and the role of myeloid regulatory cells in the pathogenesis and treatment of Crohn’s disease

... 3 innate lymphoid cells (ILC3s) thereby promoting intestinal ...promote intestinal myeloid cell homeostasis through enhancing DC and regulatory T cell function ...

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HIV 1 Is a Poor Inducer of Innate Immune Responses

HIV 1 Is a Poor Inducer of Innate Immune Responses

... FIG 1 Single-round infection with HIV-1 reporter virus does not induce markers of innate immune activation in A549 lung epithelial cells. (A) Overview of experimental setup. (B) A549 cells were transfected ...

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Immunological characterization and transcription profiling of peripheral blood (PB) monocytes in children with autism spectrum disorders (ASD) and specific polysaccharide antibody deficiency (SPAD): case study

Immunological characterization and transcription profiling of peripheral blood (PB) monocytes in children with autism spectrum disorders (ASD) and specific polysaccharide antibody deficiency (SPAD): case study

... conventional immune workup Most of the ASD/SPAD children suffered from chronic rhinosinusitis (CRS) and recurrent otitis media (ROM) requiring fre- quent antibiosis prior to IVIG ...

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