insulin signaling pathway
Torso-Like Is a Component of the Hemolymph and Regulates the Insulin Signaling Pathway in Drosophila
... activated signaling pathways control ecdysone production in response to environmental signals, including the insulin signaling path- way, which regulates ecdysone production in response to ...the ...
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Akt/PKB activation and insulin signaling: a novel insulin signaling pathway in the treatment of type 2 diabetes
... the insulin-signaling pathway for the treatment of insulin ...for insulin resis- tance cannot be completely disregarded, with McBride et al ...
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Zinc stimulates glucose oxidation and glycemic control by modulating the insulin signaling pathway in human and mouse skeletal muscle cell lines
... example, insulin can stimulate p38 in 3T3-L1 adipocytes, but down-regulates p38 activity in chick fore- brain neuron cells ...to insulin in skeletal muscle from non-diabetic subjects [46], we did not ...
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The TOR pathway interacts with the insulin signaling pathway to regulate C elegans larval development, metabolism and life span
... As inhibition of TOR activity induces autophagy in yeast and mammalian cells (Schmelzle and Hall, 2000), autophagy may be a major target for TOR to regulate C. elegans life span as well as dauer formation (Fig. 6B). ...
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MicroRNA profiling of diabetic atherosclerosis in a rat model
... KEGG pathway analyses indicated that the DE-miRs were significantly enriched in biological processes and pathways related to glucose and lipid metabolism (P < ...aling pathway”, “negative regulation of ...
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<p>The Role of JNk Signaling Pathway in Obesity-Driven Insulin Resistance</p>
... phosphorylate insulin receptor sub- strates (IRS) 1 and 2 at Ser/Thr residues 18 and dephosphorylate IRS-1 Tyr residues, 21 which not only prevents IRS from acti- vating downstream PI3K also the interaction of IRS ...
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Construction of a polycystic ovarian syndrome (PCOS) pathway based on the interactions of PCOS-related proteins retrieved from bibliomic data
... obesity, insulin resistance, hyperandrogenism, elevated luteinizing hormone (LH) concentrations, increased risk of type 2 diabetes mellitus, cardiovascular events and menstrual irregularities ...[3]. ...
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Identification And Rescue Of Misregulated Insulin Signaling In A Drosophila Model Of Fragile X Syndrome
... the insulin-producing cells (IPCs) of the brain is sufficient to restore normal circadian behavior and to rescue the memory deficits in the fragile X mutant ...the insulin signaling pathway ...
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The insulin/Akt pathway controls a specific cell division program that leads to generation of binucleated tetraploid liver cells in rodents
... that insulin, independent of its action on glucose signaling, controlled the extent of cytokinesis failure and thus generation of binucleated tetraploid liver ...when insulin signaling was ...
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Transcriptional response of porcine skeletal muscle to feeding a linseed-enriched diet to growing pigs
... receptor-mediated signaling, muscle organ development, fatty acid metabolic process, cell motion, regulation of glucose metabolic process, spermatogenesis and regulation of myeloid cell ...IGF-1, insulin ...
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Exploring the pathogenetic association between schizophrenia and type 2 diabetes mellitus diseases based on pathway analysis
... kine signaling in our pathway-pathway interaction net- ...interaction pathway contains G protein-coupled receptors (GPCRs) of dopamine and serotonin which have been pro- posed to play an ...
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American ginseng modulates pancreatic beta cell activities
... The mechanism for the beneficial effects of Panax quinque- folius has not been fully elucidated. According to our find- ings, Panax quinquefolius water extracts reversed an IL-1 beta induced increase of uncoupling ...
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An Insulin-like Signaling Pathway Affects Both Longevity and Reproduction in Caenorhabditis elegans
... An insulin-like signaling pathway controls ...an insulin-like signaling pathway ( Morris et ...genetic pathway, consistent with their molecular identities in a similar ...
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Regulation of the Target of Rapamycin Signaling Pathway in Saccharomyces cerevisiae
... TOR signaling pathway have provided invaluable insights into the regulation and function of this ...TOR signaling is an extensively studied pathway, the majority of studies done were on the ...
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Estrogen affects cell growth and IGF-1 receptor expression in renal cell carcinoma
... Purpose: Both obesity and gender are important etiological factors in renal cell carcinoma (RCC) development, suggesting a pivotal role of sex hormone signaling pathway and insulin-like growth factor ...
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MicroRNA involvement in mechanism of endogenous protection induced by fastigial nucleus stimulation based on deep sequencing and bioinformatics
... Microarray data of miRNAs after FNS treatment in ischemic rat cortex revealed significant changes in several miRNAs. The differential expression profile of miRNAs provides a hint of their potential functions during ...
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Neuroprotective effects and mechanism of cognitive-enhancing choline analogs JWB 1-84-1 and JAY 2-22-33 in neuronal culture and Caenorhabditis elegans
... that insulin receptor/IGF-1 receptor signaling plays a role in AD [34] and has direct effect on the metabolism and clearance of Ab ...of insulin signaling path- way, have been shown to play an ...
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In silico identification of potential key regulatory factors in smoking-induced lung cancer
... and insulin signaling; purine and ether lipid metabolism; adherens junctions; regulation of autophagy; snare interactions in vesicular transport; and cell cycle) have been previously ...
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Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent
... Multiple signaling pathways are involved in regulating cell ...the insulin pathway, are regulated by members of the protein kinase C (PKC) ...induce insulin resistance by inhibiting ...
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Original Article The impact of TLR4 on insulin resistance and inflammatory factors in rats with polycystic ovary syndrome
... 6]. Insulin resistance can lead to met- abolic abnormalities, further exacerbating tis- sue damage ...TLR4/NF-κB pathway is an important factor in inflammation ...and insulin resistance [15]. ...
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