Interferon-γ (IFN-γ)
Accuracy of the interferon γ release assay for the diagnosis of active tuberculosis among HIV seropositive individuals: a systematic review and meta analysis
... In the past 15 years, as an immunodiagnostic method, the interferon-γ (IFN-γ) release assay (IGRA) was devel- oped to distinguish patients suffering from TB. The IGRA is a blood test that ...
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Interferon-γ promotes gastric lymphoid follicle formation but not gastritis in Helicobacter-infected BALB/c mice
... that interferon-γ (IFN-γ), a T helper 1 (Th1) cytokine, is required for the development of severe pathology induced by chronic Helicobacter ...of IFN-γ in Helicobacter-induced ...
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Interferon-γ enhances the antifibrotic effects of pirfenidone by attenuating IPF lung fibroblast activation and differentiation
... myofibroblasts, IFN-γ treatment results in the inhibition of COL1A1 gene expression and total collagen secretion ...combined IFN- γ and PFD sig- nificantly inhibited fibroblast differentiation ...
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Association of genetic polymorphisms in interferon-γ, interleukin-6 and transforming growth factor-β1 gene with oral lichen planus susceptibility
... Two hundred thirty seven Saudi subjects visiting Prince Sultan Military Medical City (PSMMC), Riyadh Saudi Arabia were recruited for this study. Forty two unrelated OLP patients (16 male, 26 female) aged 27–72 years and ...
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Successful control of juvenile dermatomyositis-associated macrophage activation syndrome and interstitial pneumonia: distinct kinetics of interleukin-6 and -18 levels
... We studied serum cytokine profiles in this patient during the acute (days 4, 6), subacute (day 12) or convalescent phase (day 50) of JDM-MAS with IP. Multi-target streaming protein quantitative technology (BD-Pharmingen ...
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Original Article Auxiliary diagnostic value of γδΤ cell, IL-17, and IFN-γ levels in peripheral blood and bronchoalveolar lavage fluid for lung cancer complicated with chronic obstructive pulmonary disease
... and interferon-γ (IFN-γ) levels in peripheral blood (PB) and bronchoalveolar lavage fluid (BALF) for lung cancer complicated with chronic obstructive pulmonary disease ...and ...
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The human microglial HMC3 cell line: where do we stand? A systematic literature review
... 1; IFN γ : Interferon- γ ; II: Interferon- γ /interleukin-1 β ; IL: Interleukin; iNOS: Inducible nitric oxide synthase; IP-10: Interferon- γ inducible protein 10; ...
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Disseminated Mycobacterium avium complex infection mimicking malignancy in a patient with anti IFN γ autoantibodies: a case report
... infection. IFN-γ is synthesised by T cells and NK cells under IL-12/23 ...turn, IFN-γ can activate macrophages, which destroy intracellular ...microbes. IFN-γ/IL-12/23 axis plays ...
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MAPKAPK2: the master regulator of RNA-binding proteins modulates transcript stability and tumor progression
... cells; IFN γ : Interferon- γ ; IGF: Insulin-like growth factor; IL: Interleukin; LPS: Lipopolysaccharide; MAP2K: MAPK kinase; MAP3K: MAPK kinase kinase; MAPKAPK2 or MK2: Mitogen-activate[r] ...
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Inducible NO synthase: role in cellular signalling
... and interferon-γ (IFN-γ) are strong inducers of iNOS in monocytes, whereas the cytokines TNF- α and IL-1β have, if any, only marginal ...LPS, IFN-γ, IL-1β and TNF-α enhance iNOS ...
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Construction and evaluation of a novel humanized HER2 specific chimeric receptor
... A cytokine release assay was performed by coculture of 10 5 T cells with 10 5 target cells per well in triplicate in 96-well flat-bottom plates in a 200-μl volume of complete medium. In addition, wells containing T cells ...
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Protective effect of the methanol extract from Cryptotaenia japonica Hassk against lipopolysaccharide induced inflammation in vitro and in vivo
... pattern; IFN- γ : Interferon- γ ; NK cells: Natural killer cells; LPS: Lipopolysaccharide; NO: Nitric oxide; iNOS: Inducible nitric oxide synthase; TNF- α : Tumor necrosis factor- α ; IL-6: ...
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Original Article Detection of IL-2, IFN-γ, and serum-specific antibodies in the serum of children with atopic dermatitis
... (IL-2), interferon-γ (IFN-γ), and serum-specific antibodies in children with atopic dermatitis ...and IFN-γ in the ...and IFN-γ were compared between the two ...of ...
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Local cytokines and clinical symptoms in children with allergic rhinitis after different treatments
... of interferon-γ (IFN-γ) and interleukin-5 (IL-5) in nasal lavage fluid from children with allergic rhinitis after different types of pharmacologic treatment (mometasone, montelukast, or ...
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Aberrant expression of interleukin 23 regulated miRNAs in T cells from patients with ankylosing spondylitis
... Methods: Expression profiles of human miRNAs in K562 cells, cultured in the presence or absence of IL-23 for 3 days, were analyzed by microarray. Potentially aberrantly expressed miRNAs were validated using T-cell ...
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Susceptibility to Engineered Nanomaterial-Induced Toxicity in Mouse Models of Allergic Lung Disease.
... activation by assessing CD69 + cells by flow cytometry; in particular, alveolar macrophages and dendritic cells were found to have increased activation in silica NP/OVA treated mice compared to OVA alone [39]. Other ...
128
STAT1 modification improves therapeutic effects of interferons on lung cancer cells
... to IFN were overexpressed in lung cancer SPC-A-1 and H1299 cells using lentiviral ...with interferon-gamma (IFN-γ) or interferon-beta (IFN-β) and monitored for cell ...
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Incubation of Whole Blood at 39°C Augments Gamma Interferon (IFN-γ)-Induced Protein 10 and IFN-γ Responses to Mycobacterium tuberculosis Antigens
... e.g., IFN- ␥ , tumor ne- crosis factor alpha, IL-1, and IL-2, has been found to increase with incubation at fever-range temperatures, while the produc- tion of others, mainly Th2-specific cytokines such as IL-10, ...
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Diagnostic value of pleural fluid interferon-gamma and adenosine deaminase in patients with pleural tuberculosis in Qatar
... mean IFN-γ concentration for the group with tuberculous effusions was significantly higher than that in the group with nontubercu- lous effusions ...for IFN-γ and ADA were ...for ...
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The Sp1 transcription factor is essential for the expression of gliostatin/thymidine phosphorylase in rheumatoid fibroblast like synoviocytes
... Analysis of the TP promoter region revealed several potential zinc finger-type transcription factor Sp1-binding sites, including those in numerous housekeeping and inducible genes [18], in the ...
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