interindividual variability
New tablet formulation of tacrolimus with smaller interindividual variability may become a better treatment option than the conventional capsule formulation in organ transplant patients
... IIV, interindividual variability; IRB, institutional review board; IS, internal standard; MRM, multiple reaction monitoring; NTI, narrow therapeutic index; PK, pharmacokinetic(s); t 1/2 , terminal ...
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Canalization effect in the coagulation cascade and the interindividual variability of oral anticoagulant response. a simulation Study
... the variability of the pretreatment plasmatic factor levels and the variability of the coagulation ...of interindividual pretreatment factor variability on the INR only for patients under ...
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Brain size: a possible source of interindividual variability in corpus callosum morphology
... enormous variability in CC size across the subgroups tested, we employed whole-brain in-vivo magnetic resonance morphometry in order to investigate the anatomical relationship between CC midsagittal size and ...
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Interindividual variability in sweat electrolyte concentration in marathoners
... atypically high sweat electrolyte concentrations [43]. Figure 2 depicts individual data of sweat Na + and Cl − concentrations. Interestingly, there was a strong and linear relationship between sweat Na + and Cl − concen- ...
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Benzene metabolism in humans: dose-dependent metabolism and interindividual variability
... In the present study, we found that subjects with variant CYP2E1 (-1054C>T) produced lower levels of benzene metabolites at a given benzene exposure than homozygous wild types, an[r] ...
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Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations
... Large interindividual variability in the growth response to daily GH injections in GH-deficient children and adults reflects numerous inherent biological factors, including dosing and dose frequency and ...
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T Cell Epitope Mapping of JC Polyoma Virus-Encoded Proteome Reveals Reduced T Cell Responses in HLA-DRB1*04:01+ Donors
... of interindividual variability with respect to recognition of different peptide pools, with respect to the magnitude of the pro- liferative response, ...
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Saturable human neopterin response to interferon α assessed by a pharmacokinetic pharmacodynamic model
... A log normal distribution was assumed for interindividual variability η, and PK or PD parameters of the jth subject Pj were described as: Pj ¼ TVP exp ηj where TVP represents the typi[r] ...
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Evaluation of analgesic effect and absorption of buprenorphine after buccal administration in cats with oral disease
... The time of maximum plasma buprenorphine concentration was 30 minutes following administration 238. and pharmacokinetic analysis showed low interindividual variability with valu[r] ...
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[11C]SCH23390 binding to the D1-dopamine receptor in the human brain—a comparison of manual and automated methods for image analysis
... lower interindividual variability except for the cerebellum, which had larger variability for the automated ROI (Table ...greater interindividual variability, have recently been ...
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Second edition of SIMPAR’s “Feed Your Destiny” workshop: the role of lifestyle in improving pain management
... Nature and nurture contribute to pain and analgesic response both independently and through interplay between each other. George et al reported an example of such interplay in which different combinations of genotypes ...
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Effect of MRP2 and MRP3 Polymorphisms on Anastrozole Glucuronidation and MRP2 and MRP3 Gene Expression in Normal Liver Samples
... of interindividual variation in human liver samples which can be partially explained by UGT1A4 ...the interindividual variability could also be affected by variation in MRP2 and ...and ...
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Estimating relative intensity using individualized accelerometer cutpoints: the importance of fitness level
... The purpose of this study was to illustrate the interindividual variability in accelerometer activity counts measured at relative intensities (40 and 60% heart rate reserve (HRR)) and de[r] ...
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Neural mirroring and social interaction: motor system involvement during action observation relates to early peer cooperation
... whether interindividual differences in neural mirroring play a role in interpersonal coordination during different instances of social ...that interindividual differences in neural mirroring are related to ...
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Creating the interindividual-intergroup discontinuity effect through Campbell’s indices of entitativity
... the interindividual-intergroup discontinuity effect and has been demonstrated many times in laboratory settings (see Wildschut, Pinter, Vevea, Insko, & Schopler, 2003 for a meta-analysis of these ...
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Changes of the Rumination Characteristics in Dairy Cows After Change TMR Composition
... and interindividual stability of rumination characteristic in dairy cattle after composition change of TMR between the first month after calving (TMR 1) and the fourth month after calving (TMR ...
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Interindividual variation of eye optics and single object resolution in bumblebees
... However, behavioural experiments reveal that in single object detection tasks, such as perceiving a coloured flower against its green foliage background, a minimum angle of 5° must be su[r] ...
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Public and Private in the Social Communications: Historical and Sociological Approach
... In this article, analyzing the current ratio of public and private, interindividual, interpersonal communication in the communicative space, we turn to the history [r] ...
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GENETIC HETEROGENEITY OF RABBIT ALPHA-1-ANTITRYPSIN
... We found interindividual differences in the electrophoretic A-1-AT patterns as well as quantitative differences in the concentrations of A-1-AT and the serum trypsin-inhibit[r] ...
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Evaluating intra and inter individual variation in the human placental transcriptome
... or variability parameters Nst, Nit, and ...the variability in gene ex- pression is found among populations of cells within a single tissue (Net, permutation of reads among replicates, P = ...the ...
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