Interleukin, IL
Role of Interleukin 1 Alpha (IL 1α) and Interleukin 1 Receptor Antagonist (IL 1RA) in Pathogenesis of Juvenile Idiopathic Arthritis and Adult Onset Rheumatoid Arthritis of Iraqi Patients
... and IL-1RA in both diseases with special reference to JIA, because the two cytokines have not been determined in Iraqi JIA ...patients. Interleukin-1 is an inflammatory cytokine that has multiple properties ...
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The involvement of proinflammatory cytokines in diabetic nephropathy: Focus on interleukin 1 (IL-1), interleukin 6 (IL-6), and tumor necrosis factor-alpha (TNF-α) signaling mechanism
... Interleukin 1 is one of proinflammatory cytokines which predicted to be involved in inflamma- tion-based disease e.g. sepsis, autoimmune disease, including DN. The two main ligands are IL-1α and ...
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Mass Spectrometric Analysis of the Endogenous Type I Interleukin 1 (IL 1) Receptor Signaling Complex Formed after IL 1 Binding Identifies IL 1RAcP, MyD88, and IRAK 4 as the Stable Components
... I interleukin-1 (IL-1) receptor (IL-1RI) signaling complex using immunoprecipitation and tandem mass ...to interleukin-1 receptor-associated kinase ...of IL-1, IL-1RI, ...
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Relationship between Cysteine, Interleukin (IL)-2, And Interleukin (IL)-10 in Children with Marasmus Type Malnutrition
... as IL-2 and conversely, NAC decreased the activation of T-depen- dent B cell which produced cytokine such as IL-10 ...[26]. IL-10 inhibited the activation of T lymphocyte, so the cellular immunity ...
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High-density Lipoprotein Increases the Uptake of Oxidized Low Density Lipoprotein via PPARγ/CD36 Pathway in Inflammatory Adipocytes
... Methods and Results: 3T3-L1 adipocytes were cultured and induced to differentiation and maturation. Acute inflammation in adipocytes was induced by LPS (100 ng/ml) for 6 hours. The adipocytes were pretreated with HDL in ...
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Immunotherapy of brain metastases: breaking a “dogma”
... Indeed, interleukin (IL) -8, macrophage migration in- hibitory factor (MIF), and plasminogen activator inhibitor-1 (PAI-1) released by metastatic lung cancer cells were found to be able to activate ...
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The effects of highly active antiretroviral therapy on the serum levels of pro-inflammatory and anti-inflammatory cytokines in HIV infected subjects
... produce IL-2 and ...as interleukin (IL-2) and interferon gamma (IFN-γ) are gen- erally decreased, whereas production of T helper 2 (Th 2) cytokines IL-4, IL-10, proinflammatory ...
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Determination of Changes in Blood Biomarker Levels in Antipsychotic Polypharmacy and Aripiprazole Monotherapy in Patients With Long-term Schizophrenia
... as Interleukin 2 (IL-2) and Inter- leukin 6 (IL-6) are altered in the serum of schizophrenic patients with an upstream regulation of inflammatory cytokines and some of their receptors, such as ...
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Distribution of interleukin-1 receptor complex at the synaptic membrane driven by interleukin-1β and NMDA stimulation
... that IL-1RI and its accessory proteins MyD88 and IL-1RAcP are differently distributed in the hippocampus and in the subcellular compartments of primary hippocampal ...only IL-1RI is enriched at ...
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Original Article Effects of glutamine on alveolar epithelial barrier function after cardiopulmonary bypass
... (RI), interleukin-6 (IL-6), interleukin-10 (IL-10), tumornecrosisfactor-α (TNF-α), lipopolysaccharide (LPS), matrix metalloprotein-9 (MMP-9), extravascular lung water (EVLW), malonic ...
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An overview of curcumin in neurological disorders
... of interleukin-8 (IL-8), interleukin-1β (IL-1β) and TNF- α levels prompted us to observe its protective action in animal models of diabetic ...
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Difference in vaginal microecology, local immunity and HPV infection among childbearing-age women with different degrees of cervical lesions in Inner Mongolia
... (IgG), interleukin-2 (IL-2) and interleukin-10 (IL-10) in vaginal lavage fluid, as well as the incidence of HPV, mycoplasma and Chlamydia infection in vaginal secretions, were detected, in ...
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Original Article Effect of acupuncture on expression levels of NF-κB, IL-1β, IL-6, and TNF-α in rats with cerebral ischemia and reperfusion
... (NF-κB), interleukin -1β (IL-1β), interleukin -6 (IL-6), and tumor necrosis factor-α (TNF-α) in rats with cerebral ischemia and ...of IL-1β, IL-6, TNF-α, and NF-κB in the ...
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T lymphocyte reactivity and antibody response to a synthetic peptide (glutamic acid alanine tyrosine) as a marker for disease resistance in chickens
... Accessory cell and interleukin-mediated interactions in an immune response leading to antibody production Ag, antigen; APC, antigen presenting cell; IL-1, interleukin 1; IL-2, interleuki[r] ...
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Characterization of Immunodeficiency in a Patient With Growth Hormone Insensitivity Secondary to a Novel STAT5b Gene Mutation
... Abbreviations: IL, interleukin; GH, growth hormone; JAK, Janus kinase; STAT, signal transducer and activator of transcription; GHR, growth hormone receptor; IL-2R, interleukin 2 receptor; ...
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Molecular changes indicative of cartilage degeneration and osteoarthritis development in patients with anterior cruciate ligament injury
... cytokines interleukin-1 β (IL-1 β ) and interleukin-6 (IL-6) and degrading enzyme matrix metalloproteinase 13 (MMP-13), all indicative of cartilage degeneration and osteoarthritis development ...
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Differential expression of pro inflammatory cytokines IL 15Ralpha, IL 15, IL 6 and TNFalpha in synovial fluid from Rheumatoid arthritis patients
... cytokines interleukin 1 (IL1), tumour ne- crosis factor alpha (TNFalpha), and interleukin 6 (IL6), in particular, have been identified and intra-articular as well as systemic levels of these cytokines may ...
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Assessment of Pro-Inflammatory Cytokines Level in Stored Blood for Transfusion in Port Harcourt, Nigeria
... where interleukin-6 showed a decreased trend from day 1 to day 35 in whole blood ...found IL-6 levels in physiological limits in whole blood [5] ...that IL-6 was under the detection limit of ...that ...
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Immunomodulatory factors gene polymorphisms in chronic periodontitis: an overview
... as Interleukin-1 and Tumor necrosis factor alpha; as pro-inflammatory cytokines; IL-6, IL-10; as regulatory cytokines; VDR; as a connective tissue metabolism-associated-gene; that are associated with ...
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Interleukin-1 associations in inflammatory bowel disease and the enteropathic seronegative spondylarthritis
... Proinflammatory cytokines, particularly tumor necrosis factor alpha (TNFa) and interleukin-1 (IL-1), are found to play a pivotal role during the acute phase response. Although treatment may modify the ...
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