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Interstitial Lung Diseases (ILDs)

Pulmonary hypertension in chronic interstitial lung diseases

Pulmonary hypertension in chronic interstitial lung diseases

... of interstitial lung diseases (ILDs), particularly in idiopathic pulmonary fibrosis and ILD associated with connective tissue ...other lung diseases, such as combined pulmonary fibrosis ...

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Role of imaging in progressive-fibrosing interstitial lung diseases

Role of imaging in progressive-fibrosing interstitial lung diseases

... ABSTRACT Imaging techniques are an essential component of the diagnostic process for interstitial lung diseases (ILDs). Chest radiography is frequently the initial indicator of an ILD, and comparison ...

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Long-term macrolides in diffuse interstitial lung diseases

Long-term macrolides in diffuse interstitial lung diseases

... ABSTRACT In the present review we provide currently available evidence for the use of macrolides in the treatment of diffuse interstitial lung diseases (ILDs). Up to now, research on macrolides has ...

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Non-invasive mechanical ventilation in patients with diffuse interstitial lung diseases

Non-invasive mechanical ventilation in patients with diffuse interstitial lung diseases

... tissue diseases; ECMO: Extra-corporeal membrane oxygenation; ETI: Endotracheal intubation; HDU: High dependency units; HP: Hypersensitivity pneumonitis; HRCT: High resolution CT; ICU: Intensive care unit; DILD: ...

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Personalised medicine in interstitial lung diseases

Personalised medicine in interstitial lung diseases

... ABSTRACT Interstitial lung diseases in general, and idiopathic pulmonary fibrosis in particular, are complex disorders with multiple pathogenetic pathways, various disease behaviour profiles and ...

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Endotoxin markers in bronchoalveolar lavage fluid of patients with interstitial lung diseases

Endotoxin markers in bronchoalveolar lavage fluid of patients with interstitial lung diseases

... diffuse lung dis- ...smoking-related interstitial lung diseases (sr-ILD) (n = 11, mean age 53 ...and lung fibrosis (n = 42, mean age 62 ...of interstitial lung dis- eases ...

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Increased Levels of Hyaluronic Acid in Bronchoalveolar Lavage from Patients with Interstitial Lung Diseases, Relationship with Lung Function and Inflammatory Cells Recruitment

Increased Levels of Hyaluronic Acid in Bronchoalveolar Lavage from Patients with Interstitial Lung Diseases, Relationship with Lung Function and Inflammatory Cells Recruitment

... Purpose: Interstitial Lung Diseases (ILD) are characterized by inflammation and fibrosis. It de- scribed the role of hyaluronic acid (HA) as an immune-regulator. It is not known if HA contri- butes ...

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Angiogenesis in Interstitial Lung Diseases: a pathogenetic hallmark or a bystander?

Angiogenesis in Interstitial Lung Diseases: a pathogenetic hallmark or a bystander?

... 4. Pathogenetic pathways during aberrant angiogenesis Several transcription factors play instrumental role in pro- moting angiogenesis and sensing the environmental cues that drive this process. Strieter et al. [22] ...

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Management of acute respiratory failure in interstitial lung diseases: overview and clinical insights

Management of acute respiratory failure in interstitial lung diseases: overview and clinical insights

... Results: In managing ARF, it is important to establish an adequate diagnostic and therapeutic management depending on whether the patient has an underlying known chronic ILD or ARF is presenting in an unknown or de novo ...

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Surfactant gene polymorphisms and interstitial lung diseases

Surfactant gene polymorphisms and interstitial lung diseases

... chronic lung disease of unknown origin (Nogee et ...the lung disease. This suggests that SP-C is necessary for normal lung function in the postnatal ...

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Cellular interactions in the pathogenesis of interstitial lung diseases

Cellular interactions in the pathogenesis of interstitial lung diseases

... in part by the expression of the scavenger receptor CD163, the IL-1RII decoy receptor and mannose receptors, and by increased IL-10, C-C chemokine ligand (CCL)18 and pulmonary activation-regulated chemokine (PARC) ...

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Fibrosing interstitial lung diseases: knowns and unknowns

Fibrosing interstitial lung diseases: knowns and unknowns

... HP is a complex syndrome caused by sensitisation to an inhaled antigen that leads to an aberrant immune response in the small airways and lung parenchyma. Susceptibility is believed to be affected by genetics, ...

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Acute exacerbations of progressive-fibrosing interstitial lung diseases

Acute exacerbations of progressive-fibrosing interstitial lung diseases

... AE of ILDs that may present a progressive-fibrosing phenotype is an unpredictable serious life-threatening event that can occur at any time during the disease course. Data on the incidence of AE in ILDs that may present ...

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The natural history of progressive fibrosing interstitial lung diseases

The natural history of progressive fibrosing interstitial lung diseases

... Data from clinical trials of investigational therapies made a large contribution to our understanding of the clinical course of IPF [104]. Ongoing large clinical trials con- ducted in patients with non-IPF fibrosing ILDs ...

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Spectrum of HRCT findings in interstitial lung diseases and their correlation with mediastinal lymphadenopathy

Spectrum of HRCT findings in interstitial lung diseases and their correlation with mediastinal lymphadenopathy

... Background: Interstitial lung disease (ILD) represents a heterogeneous non-infectious group of acute and chronic diseases affecting the lung ...

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Interstitial Lung Diseases Associated with Connective Tissue Pathologies: Radiologic Features

Interstitial Lung Diseases Associated with Connective Tissue Pathologies: Radiologic Features

... tissue diseases (CTD) represent a heterogeneous group of dysim- mune inflammatory diseases that can affect a large number of organs, particu- larly ...unknown. Interstitial in- volvement is one of ...

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An integrated approach in the diagnosis of smoking-related interstitial lung diseases

An integrated approach in the diagnosis of smoking-related interstitial lung diseases

... contrast, lung biopsy is generally required to diagnose DIP as the HRCT aspects of extensive ground-glass attenuation and the highly cellular BAL profile are both nonspecific ...other interstitial disease ...

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Serum biomarkers in interstitial lung diseases

Serum biomarkers in interstitial lung diseases

... other lung disorders ...of lung disease and correlated relatively well with the disease severity, however they failed to serve as reliable prognosticators of decline or responsiveness to therapy whereas ...

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Interstitial lung diseases in the hospitalized patient

Interstitial lung diseases in the hospitalized patient

... differentiating lung infection from an acute presentation of ILD or acute exacerbation of preexisting ILD, treatment with broad-spectrum antibiotics should be considered in all ...

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Comorbidities in interstitial lung diseases

Comorbidities in interstitial lung diseases

... In interstitial lung disease (ILD), recent treatment advances have led to more purposeful management and an expectation of better outcomes than in historical ...

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