intracellular Ca2+ concentration
Mitochondria, calcium, and tumor suppressor Fus1: At the crossroad of cancer, inflammation and autoimmunity
... Roles of mitochondria, calcium, and Fus1 in tumorigenesis and immunity Mitochondrial Ca2+ transport and tumorigenesis Changes in intracellular Ca2+ concentration are used as a universal [r] ...
19
Effects of temperature on intracellular [Ca2+] in trout atrial myocytes
... To better understand the acute effects of temperature on the ectothermic heart, we investigated the stimulus-induced change in intracellular Ca2+ concentration [Ca2+]i; cytosolic Ca2+ tr[r] ...
10
Mechanism of the diastolic dysfunction induced by glycolytic inhibition Does adenosine triphosphate derived from glycolysis play a favored role in cellular Ca2+ homeostasis in ferret myocardium?
... of intracellular Ca2+, myocardial content of sugar phosphates ([SP]) and intracellular Ca2+ concentration ([Ca2+]i) were measured in isolated, perfused ferret hearts using ...
9
Intracellular Free Calcium Measured with Calcium Selective Microelectrodes from Salivary Gland Cells of the Snail Planorbis Corneus
... SUMMARY Double-barrelled Ca2+-selective microelectrodes-have been used to make simultaneous measurements of the intracellular concentration of free Ca 2+ [Ca 2+ ]j and membrane potential[r] ...
12
Chain reaction Ca2+ signaling in the heart
... On a beat-to-beat basis, Ca 2+ entry through voltage-gated Ca 2+ Nonstandard abbreviations used: [Ca2+]i, cytosolic Ca2+ concentration; [Ca2+]SR, SR Ca2+ concentration; CASQ2, calsequest[r] ...
6
Altered cardiac excitation–contraction coupling in mutant mice with familial hypertrophic cardiomyopathy
... Excitation–contraction coupling in cardiac muscle of familial hypertrophic cardiomyopathy (FHC) remains poorly understood, despite the fact that the genetic alterations are well defined. We characterized calcium cycling ...
7
Altered intracellular Ca2+ handling in heart failure
... This Ca2+ influx triggers a large-scale Ca2+ release through the Ca2+ release channel of the sarcoplasmic reticulum SR, Nonstandard abbreviations used: ARVD/C2, arrhythmogenic right vent[r] ...
10
Endothelin induced increases in vascular smooth muscle Ca2+ do not depend on dihydropyridine sensitive Ca2+ channels
... dihydropyridine-sensitive Ca2+ channels in cultured vascular smooth muscle (VSM) ...cell Ca2+ can be altered in VSM by activation of voltage- operated Ca2+ ...dihydropyridine Ca2+ channel ...
6
Silencing of Rotavirus NSP4 or VP7 Expression Reduces Alterations in Ca2+ Homeostasis Induced by Infection of Cultured Cells
... ⴙ concentration, and total cell Ca 2 ⴙ content and a reduction in the amount of Ca 2 ⴙ released from intracellular pools sensitive to ...ⴙ concentration measured in infected ...
10
Intracellular acidification associated with changes in free cytosolic calcium Evidence for Ca2+/H+ exchange via a plasma membrane Ca(2+) ATPase in vascular smooth muscle cells
... The purpose of this study was to define the mechanism whereby agonists that increase free cytosolic calcium (Cai2+) affect intracellular pH (pHi) in smooth muscle. Rat aortic vascular smooth muscle cells grown on ...
11
Na+/Ca2+ exchange mediated calcium entry in human lymphocytes
... on Ca2+ regulation in human peripheral blood lymphocytes, Ca2+ entry and cytosolic Ca2+ (measured with fura- 2) were monitored in cells in which cytosolic Na+ was increased and/or the Na+ gradient ...
8
Elevated intracellular Ca2+ acts through protein kinase C to regulate rabbit ileal NaCl absorption Evidence for sequential control by Ca2+/calmodulin and protein kinase C
... elevated intracellular Ca2+ affects Na and Cl transport is ...the Ca2+/calmodulin and protein kinase C systems in ileal NaCl transport, two drugs, the isoquinolenesulfonamide, H-7, and the ...
11
Spontaneous Ca2+ transients in rat pulmonary vein cardiomyocytes are increased in frequency and become more synchronous following electrical stimulation
... high concentration of ryanodine (20 µM) abolished the spontaneous Ca 2+ transients in the majority of cardiomyocytes in the rat pulmonary vein [15], which is consistent with the notion that Ca 2+ waves occur due ...
42
Interdependence of Ca2+ and proton movements in trout hepatocytes
... To explore the underlying mechanisms for a similar alkalinization, various inhibitors of the acid-transporting mechanisms have often been used, and the amount of protons transferred across the cell membrane has been ...
11
Intracellular calcium and survival of tadpole forebrain cells in anoxia
... neurotransmitters GABA and glutamate. Thus, the ‘slow death’ of the anoxic frog brain exhibits all the hallmarks of acute energy failure, similar to that seen in mammals, but on a significantly extended time scale ...
6
UTP is not a biased agonist at human P2Y11 receptors
... Biased agonism describes a multi-state model of G protein-coupled receptor activation in which each ligand induces a unique structural conformation of the receptor, such that the receptor couples differentially to G ...
12
Effects of polyphenols and lipids from Pennisetum glaucum grains on T cell activation: modulation of Ca2+ and ERK1/ERK2 signaling
... T-lymphocytes represent a fundamental component of the adaptive immune response. The lymphocyte trans- formation assay is an important tool to measure, in vitro, mitogen-induced lymphocyte proliferation [48, 49]. Fol- ...
11
Translating intracellular calcium signaling into models
... on intracellular calcium has put theoreticians in an ideal position to derive models of intracellular calcium ...of intracellular calcium modeling with a special emphasis on calcium-induced-calcium ...
14
Review Article Ca 2+ and ion channels in hypoxia-mediated pulmonary hypertension
... Sustained pulmonary vasoconstriction and excessive pulmonary vascular remodeling are the major causes for the elevated pulmonary vascular resistance. Although previous studies have characterized some of the functional ...
12
Distinct intracellular Ca2+ dynamics regulate apical constriction and differentially contribute to neural tube closure
... In this study, we show that intracellular calcium ions Ca2+ are required for Xenopus neural tube formation and that there are two types of Ca2+concentration changes, a single-cell and a [r] ...
10