Ischemia Reperfusion Injury
Original Article Role of miRNA-185 in cerebral ischemia-reperfusion injury
... ischemic injury, but reperfusion injury may occur ...in ischemia-reperfusion injury ...emia-reperfusion injury, and to research devel- opment drugs for the ...
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New Naphthalene-Derivative as Cardioprotector Drug on the Ischemia/Reperfusion Injury
... There is scarce information about the effects exerted by the naphthalene derivatives on cardiac injury caused by ischemia/reperfusion. In this study, a new naphthalene derivative was synthetized with ...
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Protective effect of picroside II on myocardial ischemia reperfusion injury in rats
... Abstract: The aim of this study was to determine the effect of picroside II on myocardial ischemia reperfusion injury in rats and to explore its underlying mechanism. Isolated rat hearts underwent 30 ...
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Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury
... Our study suggests a role for mitochondrial PINK1 as a target for cardioprotection in the heart. This mitochondrial protein appears to be required for endogenous protection against SIRI, as its genetic ablation resulted ...
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Leukotrienes as mediators in ischemia reperfusion injury in a microcirculation model in the hamster
... after ischemia-reperfusion, suggesting a role of leukotrienes as mediators of ischemia-reperfusion ...after ischemia and reperfusion, and that (c) selective inhibition of ...
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Myocardial ischemia reperfusion injury: a neglected therapeutic target
... myocardial ischemia-reperfusion injury ...ischemic injury and limiting the size of myocardial infarction (MI) is timely and effective myocardial reperfusion using either thrombolytic ...
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Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation
... Ischemia/reperfusion injury belongs to the main reasons for inflammatory reactions in solid organ allografts with profound influence on acute as well as long-term graft ...I/R injury fea- ...
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TLR4 activation mediates kidney ischemia/reperfusion injury
... Ischemia/reperfusion injury (IRI) may activate innate immunity through the engagement of TLRs by endogenous ligands. TLR4 expressed within the kidney is a potential mediator of innate activation and ...
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Inadequate ubiquitination proteasome coupling contributes to myocardial ischemia reperfusion injury
... myocardial ischemia-reperfusion injury (IRI), but the molecular basis of UPS impairment remains poorly ...myocardial ischemia-reperfusion, young Ubqln1-CKO mice showed substantially ...
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RIVAROXABAN IMPROVES MYOCARDIAL ISCHEMIA REPERFUSION INJURY COMPLICATIONS IN OBESE RATS
... ischemic reperfusion injury (IRI) in a rat model of ...Myocardial ischemia was induced by left anterior descending artery ligation ...myocardial ischemia reperfusion ...
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Antioxidant Activity of Benincasa Hispida on Renal Ischemia/Reperfusion Injury
... renal ischemia/reperfusion ...renal ischemia/reperfusion injury in ...renal ischemia and were continuing for one day after ...the reperfusion period, rats were ...In ...
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TREM2 protects against cerebral ischemia/reperfusion injury
... In the current study, we demonstrated that TREM2 ex- pression was enhanced in cultured primary microglia cells after OGDR and in mouse brain after MCAO and that this increased TREM2 mainly occurred in microglia. Both in ...
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The Effect of High Dose Melatonin on Cardiac Ischemia reperfusion Injury
... reperfusion-induced arrhythmias in the isolated rat heart model has been reported, and it has been found that melatonin is a potent agent in pro- tecting against ischemia-reperfusion injury. ...
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Effect of metoprolol on hepatic ischemia reperfusion injury
... causes ischemia-reperfusion injury in the ...During ischemia period occurs depletion of cellular energy, accumulation of intracellular sodium, calcium, and reactive oxygen species, and ...
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Immune mechanisms of ischemia reperfusion injury in transplantation
... related ischemia, as well as the measurement of several parameters—flow, resistance, lactate excretion, alfa GST —which may be useful to assess the extent of ischemic ...from ischemia-reperfusion ...
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EFFECT OF ETANERCEPT AGAINST MYOCARDIAL ISCHEMIA/REPERFUSION INJURY IN MALE MICE
... cardiac injury during early reperfusion 5 . In the ischemia/reperfusion injury tissue, the intracellular calcium and ROS level will increased, these factors all contribute to induce ...
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Dexmedetomidine provides renoprotection against ischemia reperfusion injury in mice
... ischemic reperfusion injury in our previous studies ...of injury with marked cell death (60% reduction in viability) occurring after 180-minutes OGD ...
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Predominant role for C5b 9 in renal ischemia/reperfusion injury
... products of activated endothelium (8). C activation releases a number of biologically active products, sever- al of which possess proinflammatory activity in vitro. The early products C4a, C3a, and C5a, the anaphylatox- ...
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Renal associated TLR2 mediates ischemia/reperfusion injury in the kidney
... cellular injury, such as degradation products of macromolecules, products of proteolytic cascades, intracellular components of ruptured cells, and products of genes that are activated by inflammation ...cellular ...
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RhoA protects the mouse heart against ischemia/reperfusion injury
... activated in CA-RhoA hearts. The cardioprotection afforded by RhoA was reversed by PKD inhibition. The hypothesis that activated RhoA and PKD serve protective physiological functions during I/R was supported by several ...
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