Islet-cell antibodies
ISLET CELL ANTIBODIES IN DIABETES MELLITUS
... when Islet Cell Antibodies (ICAs) were detected in patients with diabetes mellitus together with autoimmune polyendocrine deficiencies 1 , and in diabetics with coexistent autoimmune disease 2 ...and ...
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Islet cell antibodies predict insulin dependent diabetes in United States school age children as powerfully as in unaffected relatives
... Discussion Our prospective study documents that it is not only feasible to predict IDD among a general population of schoolchildren, but that the rate of progression to IDD in ICA-positi[r] ...
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Glutamate decarboxylase , insulin , and islet cell antibodies and HLA typing to detect diabetes in a general population based study of Swedish children
... Predictive value of islet cell and insulin autoantibodies for Type I diabetes mellitus in a population based study of newly diagnosed diabetic and matched control children.. High genetic[r] ...
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Type 1 Diabetes Mellitus and Epilepsia Partialis Continua in a 6-Year-Old Boy With Elevated Anti-GAD65 Antibodies
... and islet cell antibodies were reported as negative (both tests performed in Barcelona, Spain, by Guillem ...Moxness). Islet cell antibody titers at this time were positive at 10 240 ...
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Metabolic Syndrome in Type 1 Diabetes
... beta cell destruction caused by an autoimmune process, usually leading to absolute insulin deficiency 1 ...with islet cell antibodies and often have other autoimmune ...
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Prediction of insulin dependent diabetes mellitus in siblings of children with diabetes A population based study The Childhood Diabetes in Finland Study Group
... of islet cell antibodies (ICA), antibodies to the IA-2 protein (IA-2A), antibodies to the 65-kD isoform of glutamic acid decarboxylase (GADA), insulin autoantibodies (IAA), and ...
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Long latency between GAD-antibody detection and development of limbic encephalitis – a case report
... cytoplasmic islet cell antibodies and of anti-glutamate decarboxylase (GAD) 65 antibodies were observed as an incidential finding, GAD67 antibodies were negative at that ...GAD ...
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Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD65) shows that 64K autoantibody positivity at onset predicts diabetes type
... electrophoresis, but converted to one under stronger reduction. Immunoprecipitation was linear with respect to antibody or antigen concentration. In 120 population-based diabetic patients of all ages grouped by treatment ...
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Study on the prevalence of glutamic acid decarboxylase antibodies in type 1 diabetic children.
... on Islet Cell Antibodies represent autoimmune response against several ...decarboxylase antibodies (GADA), thyrosine phosphatase antibodies (IA-2A) or insulin autoantibodies ...
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Diabetic Autoimmune Markers in Children and Adolescents With Type 2 Diabetes
... positive islet cell antibodies (ICAs), glutamic acid decar- boxylase antibodies (GADs), and insulin autoantibodies (IAAs) at diagnosis in both ...
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FUNCTIONING ISLET CELL ADENOMA IN THE NEWBORN
... ml, and died 8 hours after admission. An islet cell adenoma was found at autopsy. Saulsbo has studied one infant who had the onset of persistent hypoglycemia at 36 hours of age and had a[r] ...
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Pancreatic β- and α-cell adaptation in response to metabolic changes
... The liver plays a central role in glucose homeostasis, as it is one of the primary sites for storage of glucose and generation of glucose from noncarbohydrate precursors, processes that are regulated by insulin and ...
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β-cell insulin receptor deficiency during in utero development induces an islet compensatory overgrowth response
... Pancreatic development requires temporal regulation of both transcription factor expression and external signaling pathways to generate physiologically functional adult islets [13, 14]. In particular, the structural ...
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ISLET CELL ADENOMA IN CHILDHOOD: REPORT OF A CASE
... The findings of hypoglycemia precipitated by fasting, hypoglycemia regu- lanly induced following oral glucose inges- tion, and the pathological response to intra- venous tolbutamide are [r] ...
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Islet cell autoantigens in insulin dependent diabetes
... of islet cells and the continuous variation in their activity, it is reasonable to speculate that the speed of the progression to IDD could vary between individuals with respect to their insulin needs and the ...
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Antidiabetic effects of Eucalyptus globulus on pancreatic islets: a stereological study
... beta cell protective effects of sodium tungstate also showed that the number of islets was almost constant in all groups ...entire islet [27], thus there was not any significant reduction in the number of ...
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Cystic fibrosis–related diabetes is caused by islet loss and inflammation
... β cell secretory ...β cell dysfunction in both wild-type and CFTR-knockout ferret islets, indicating nonspecific effects of this CFTR inhibitor ...β cell CFTR function has used human islets, was ...
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Association of insulin, C-peptide and blood lipid patterns in patients with impaired glucose regulation
... of islet cells increase with normal islet cell structure and gene expression, which can be designated as the islet cell functional compensatory ...the islet cell to ...
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Islet β cell failure in type 2 diabetes
... b cell compensation for insulin resistance, consideration is also given to the mechanisms involved in the compensation process, including mechanisms for expansion of b cell mass and for enhanced b ...
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NKX6.1 transcription factor: A crucial regulator of pancreatic -cell development, identity, and proliferation
... 28. Seymour PA, Freude KK, Tran MN, et al. SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc Natl Acad Sci U S A. 2007;104(6):1865-1870. 29. Lyttle BM, Li J, Krishnamurthy M, et al. ...
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