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An investigation of the regulation and role of c-Jun during neuronal apoptosis

An investigation of the regulation and role of c-Jun during neuronal apoptosis

... Cell death by apoptosis plays a critical role during the development of the nervous system and there is increasing evidence that neurons die by apoptosis in neurodegenerative diseases. Developing sympathetic neurons ...

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XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell

XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell

... factors in various stable transfectants of T24T and UMUC3 cell lines as indicated in Fig. 4c. Among these transcription factors tested, the levels of RelB, p100 pro- tein, and c-Jun phosphorylation (Ser63/73) were ...

13

Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease

Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease

... tamoxifen efficiently induced Cre-mediated deletion of JunB and/or Jun in the basal layer of the epidermis. Adult single- mutant and double-mutant mice and their littermate controls were injected with tamoxifen ...

10

Activation of Jun kinase is an early event in hepatic regeneration

Activation of Jun kinase is an early event in hepatic regeneration

... Compensatory hepatic regeneration after partial hepatectomy (PH) is dependent upon the extent of resection. This study analyzes the regulation of the AP-1 transcription factor c-Jun during hepatic regeneration. ...

9

C Jun N terminal kinases/c Jun and p38 pathways cooperate in ceramide induced neuronal apoptosis

C Jun N terminal kinases/c Jun and p38 pathways cooperate in ceramide induced neuronal apoptosis

... Transient transfection of primary cortical cultures was performed with LipofectAMINE 2000 (Invitrogen, Groningen, The Nether- lands) as recommended by the manufacturer’s protocol. Cells were transfected with 1 ␮g of ...

11

Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury

Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury

... decreases JUN and DDIT3 expression and 3) if deficiency of these molecules protects RGC somas and their ...by Jun deficiency and about 50% more protection then provided by Ddit3 ...Like Jun ...

13

Transforming growth factor beta (TGF-β) is activated by the CtBP2-p300-AP1 transcriptional complex in chronic renal failure

Transforming growth factor beta (TGF-β) is activated by the CtBP2-p300-AP1 transcriptional complex in chronic renal failure

... Figure 2. Knockdown of AP-1 subunits caused the downregulation of TGFB1. (A) The promoter of TGFB1 contained one AP-1 and four NF-κB binding sites. A 1500 bp-length TGFB1 promoter was selected and applied to predict ...

12

EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma

EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma

... possibly modulate the HIF-1 protein level transcriptionally or post-transcriptionally. Herein the results showed that DZ1 blocked activity associated with phosphorylation of JNKs and suppressed both LMP1-induced total ...

14

2 D georesistivity structure in the central part of the northeastern Japan arc

2 D georesistivity structure in the central part of the northeastern Japan arc

... The survey design and measurement procedures are de- scribed in Fujinawa et al. (1997). The previous model used broadband magnetotelluric data acquired at 78 observation sites in the central part of the northeastern ...

12

The impact of mandatory policies on ETD acquisition

The impact of mandatory policies on ETD acquisition

... Griffith University Submissions after Jun 2002 Murdoch University Submissions after 2003 University of Wollongong Submissions after Jun 2003 University of Queensland Submissions after[r] ...

11

Epstein-Barr Virus Latent Membrane Protein 2A Regulates c-Jun Protein through Extracellular Signal-Regulated Kinase

Epstein-Barr Virus Latent Membrane Protein 2A Regulates c-Jun Protein through Extracellular Signal-Regulated Kinase

... of Jun may contribute to its oncogenicity (20, ...some Jun-mediated signaling probably occurs in these ...Furthermore, Jun harbors oncogenicity in that it is capable of transforming chicken embryo ...

6

Profitability Analysis of Cement Companies in Telangana – A Study of  Select Units

Profitability Analysis of Cement Companies in Telangana – A Study of Select Units

... In the period of study the compound annual growth rate of gross profit is 11 per cent compared to 10.19 compound annual growth rate for sales revenue.. During the period of stud[r] ...

11

A study on Customer Relationship management of Banking Sector with special reference to Commercial Banks in Cuddalore

A study on Customer Relationship management of Banking Sector with special reference to Commercial Banks in Cuddalore

... As a conclusion to this study it is found that, the majority of the bank employees need required facilities and technology to maintain good relationship with customers [r] ...

7

Gender discrimination in Mahesh Dattani’s Plays “Dance like a Man and Tara”

Gender discrimination in Mahesh Dattani’s Plays “Dance like a Man and Tara”

... Dance Like a Man has also been filmed by Pamela Rooks; starring Anushka Shankar as Lata Parekh, Mohan Ahashe as Amritlal Parekh, Arif Zakaria as Jairaj Parekh, Shoban[r] ...

7

Women Workers in Unorganised Sector – A Study

Women Workers in Unorganised Sector – A Study

... Women form an integral part of the Indian workforce. Education helps women to move away from agriculture and household activities to employment in the secondary and ter[r] ...

5

A survey on feature selection to perform classification using Meta Heuristic algorithms in Data Mining Domain

A survey on feature selection to perform classification using Meta Heuristic algorithms in Data Mining Domain

... Feature Selection. A Survey on Feature Selection Techniques & Classification Algorithms for Efficient Text Classification. A Survey of Feature Selection and Feature E[r] ...

12

Digitalization and job satisfaction among bank employees : A comparative study of Public and Private sector banks

Digitalization and job satisfaction among bank employees : A comparative study of Public and Private sector banks

... Table shows the Bayesian independent sample t-test result; here the null hypothesis is public sector bank operatives’ job satisfaction is greater than the private bank work[r] ...

12

A Study on HRM Practices in Public Sector Banks in Tirunelveli District

A Study on HRM Practices in Public Sector Banks in Tirunelveli District

... Human resource management (HRM) has emerged as a major function in organizations. HRM is the organizational function that deals with issues related to people such as, hirin[r] ...

6

The Candor and Probity of Employer Branding Strategies and Statutory Compliance of H.R Policies in Maintaining Delighted Employees at Flipkart - A Case Study

The Candor and Probity of Employer Branding Strategies and Statutory Compliance of H.R Policies in Maintaining Delighted Employees at Flipkart - A Case Study

... There are various statutory acts defined for the benefit of employees like factories act, 1948 (Safety, Health and Sanitary facilities), the employees’ provident funds and m[r] ...

7

Computational Intelligence in Manufacturing Handbook   Jun Wang pdf

Computational Intelligence in Manufacturing Handbook Jun Wang pdf

... Five of these tools are reviewed in this chapter with examples of applications in engineering and manufacturing: knowledge-based systems, fuzzy logic, inductive learning, neural networks[r] ...

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