lamellar bodies
A small key unlocks a heavy door : the essential function of the small hydrophobic proteins SP B and SP C to trigger adsorption of pulmonary surfactant lamellar bodies
... “unexpanded lamellar bodies” in the alveolar lining fluid and suggested an interference with their normal ability to transform into a surface active film (Fujita et ...These lamellar bodies ...
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Analysis of Labeling and Clearance of Lung Surfactant Phospholipids in Rabbit: EVIDENCE OF BIDIRECTIONAL SURFACTANT FLUX BETWEEN LAMELLAR BODIES AND ALVEOLAR LAVAGE
... administration. Phosphatidylglycerol was pulse labeled by intravenous [ 32 P]phosphate and [ 3 H]palmitate, followed by myoinositol. The biological half-lives of phosphatidylglycerol in the microsomal fraction, ...
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Predicting lung maturity in preterm rupture of membranes via lamellar bodies count from a vaginal pool: a cohort study
... a lamellar bodies (LB) count by drawing amniotic fluid from a vagi- nal pool and calculated a cutoff for LB concentration above which fetal lung maturity is ...
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Isolation and characterization of two hydroxyproline containing glycoproteins from normal animal lung lavage and lamellar bodies
... Two glycopeptides, present in particulate material obtained by pulmonary lavage from normal rabbits, were isolated and characterized. The same two glycopeptides were present in preparations of lamellar ...
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Lung Surfactant in an Era of Replacement Therapy
... Lung surfactant is synthesized in the lamellar bodies of type II cells. The lamellar body of the type II pneumocyte is[r] ...
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Nomenclature clarification: synovial fibroblasts and synovial mesenchymal stem cells
... characteristic lamellar bodies (LBs), which indicated that synovium-derived MSCs may originate from the synovial intima, as they have a phenotype highly similar to that of type B ...
7
Exogenous gene transfer of Rab38 small GTPase ameliorates aberrant lung surfactant homeostasis in Ruby rats
... [ 3 H]PC, as indicated by decreased basal secretion and remarkably amplified agonist-induced secretion. [ 3 H]PC synthesis and uptake by type II cells were not altered. The expression levels of mRNA for surfactant ...
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Actin coating and compression of fused secretory vesicles are essential for surfactant secretion a role for Rho, formins and myosin II
... Secretion of vesicular contents by exocytosis is a fundamental cellular process. Increasing evidence suggests that post-fusion events play an important role in determining the composition and quantity of the secretory ...
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Time Course of Changes in Surface Tension and Morphology of Alveolar Epithelial Cells in CO2 induced Hyaline Membrane Disease
... Atelectasis and hyaline membranes produced by exposure of guinea pigs to 15% CO, were found to be associated with disappearance of lamellar bodies in the large alveolar lining cells gran[r] ...
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Hyperoxia: A Stereologic Ultrastructural Examination of Its Influence on Cytoplasmic Components of the Pulmonary Granular Pneumocyte
... This study indicates that granular pneumocytes of rats exposed to hyperoxia have the same number of lamellar bodies as control rats but the lamellar bodies are smaller. This findings in ...
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The effect of fasting on the ultrastructure of the hypothalamic arcuate nucleus in young rats
... lysosome-like bodies present in the examined neurons. Short lamellar bodies, composed of two parallel cisternae of the RER, were occasionally observed in the ...
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Adaption to Hyperoxia: INFLUENCE ON PROTEIN SYNTHESIS BY LUNG AND ON GRANULAR PNEUMOCYTE ULTRASTRUCTURE
... the lamellar bodies occupy the same percentage of cytoplasmic volume in oxygen-exposed and control rats after 96 h; a previous study had shown lamellar bodies of oxygen-exposed rats to occupy ...
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Exogenous surfactant application in a rat lung ischemia reperfusion injury model: effects on edema formation and alveolar type II cells
... of lamellar bodies per AE2 which only reached statistical significance in the untreated ...of lamellar bodies per AE2 was increased in both I/R groups and was not altered by surfactant ...of ...
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Cholesterol synthesis is required for cutaneous barrier function in mice
... epidermal lipid synthesis which is associated with the rapid restoration of stratum corneum lipids and barrier function. The aim of this study was to determine the role of cutaneous cholesterol synthesis in the barrier ...
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Fatty acids are required for epidermal permeability barrier function
... extracellular lamellar bilayers in the stratum ...of lamellar bodies, the organelle which delivers lipid to the stratum ...secreted lamellar body material into lamellar bilayers within ...
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Degradation of dipalmitoyl phosphatidylcholine by isolated rat granular pneumocytes and reutilization for surfactant synthesis
... phospholipids by granular pneumocytes in primary culture. Cells were incubated for 21, 65, and 140 min with [3H-methyl]dipalmitoylphosphatidylcholine (DPPC) containing liposomes prepared from synthetic lipids. ...
7
The role of myosin 1c and myosin 1b in surfactant exocytosis
... fused lamellar bodies (n=28 and 38, ...fused lamellar bodies (n=18, left) and the comparison of the half-times of Myo1b – GFP and Myo1b-R165A – GFP fluorescence increase on fused vesicles ...
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Original Article Clinical characteristics and prognosis of collodion babies
... months to 9 years, with CB mainly progressing into lamellar ichthyosis and congenital ichthyo- siform erythroderma. Dry skin and systemic or focal scaly scaling deteriorated over seasons. This may have been ...
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Microstructure and Mechanical Properties of Extruded Mg Zn Y Alloys with 14H Long Period Ordered Structure
... of lamellar phase increased with increasing zinc content in the range of 0 to ...the lamellar phase in the Mg-Zn-Y alloys would exert an inhibitory effect on the dispersion of lamellar phase during ...
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The lamellar architecture of 1,6 hexamethylenediammonium tetrachlorocobaltate(II)
... In the ®eld of organic±inorganic hybrid materials, one of the most promising research areas in materials chemistry, these interactions occur within inorganic and organic components.. The[r] ...
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