Leishmania donovani
Modeling and Docking of Cysteine Protease-A (CPA) of Leishmania donovani
... Visceral Leishmaniasis (VL) is a chronic tropical disease, responsible for severe public health concern around the world. The parasitic species mainly involve in this infection are belong to protozoan Leishmania ...
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An outbreak investigation of visceral leishmaniasis among residents of Dharan town, eastern Nepal, evidence for urban transmission of Leishmania donovani
... We applied polymerase chain reaction (PCR) tech- nique as described by Bhattarai [12]. The molecular ana- lysis was done by extracting DNA from sandflies by using the QIAmp DNA minikit (Qiagen, Germany), as per the ...
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Synthesis and in vitro screening of 29, 30-dibromo-28-oxoallobetulin against parasitic protozoans, leishmania donovani and leishmania major
... on Leishmania donovani, causative agent of visceral leishmaniasis and Leishmania major, causative agent of cutaneous leishmaniasis ...L. donovani AG83 promastigote proliferation by ...L. ...
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Kinesin Motor Domain of Leishmania donovani as a Future Vaccine Candidate
... L. donovani (GenBank accession ...of Leishmania donovani expressed by the motor domain is a member of the kinesin protein superfamily ...In Leishmania donovani, it has been found to ...
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Immunoblot analysis of the humoral immune response to Leishmania donovani infantum polypeptides in human visceral leishmaniasis
... Human visceral leishmaniasis: analysis of the specificity of the humoral immune response to polypeptides of Leishmania donovani chagasi.. infantum-infected patient sera; sera infected wi[r] ...
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Screening of Anti Infectives against Leishmania donovani
... throat. Leishmania braziliensis is responsible for most cases of mucocutaneous ...the Leishmania donovani complex: L. donovani found mostly in East Africa and the Indian subcontinent and ...
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Low prevalence of Leishmania donovani infection among the blood donors in kala azar endemic areas of Bangladesh
... of Leishmania infection among blood donors in our study may be attributable to their higher socio-economic status, as demonstrated by better housing conditions, the number of rooms and bed- nets in the household ...
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Ribosome Profiling Reveals HSP90 Inhibitor Effects on Stage-Specific Protein Synthesis in Leishmania donovani
... parasite Leishmania donovani, causative agent of the fatal visceral leishmaniasis, HSP90 activity is essential for cell proliferation and ...L. donovani, comparing genome-wide protein synthesis ...
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Investacte the Role of Weissella Confuse on TNF-α in Serum and Liver Tissue of Mice Infected with Leishmania Donovani
... with Leishmania donovani induced TNF-α in infected liver, and increasing tissue TNF levels reflected both initial control over parasite replication and subsequent near resolution of visceral infection, a ...
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Coinfection of Leptomonas seymouri and Leishmania donovani in Indian Leishmaniasis
... L. donovani and Leptomonas seymouri as they gave the FIG 2 Determination of the presence of Leptomonas ...from Leishmania donovani isolates representing RFLP patterns A and ...LdA, Leishmania ...
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Immunological Study for the Role of Probiotic for Control on the Leishmania donovani
... Kefir is a fermented milk (drink) produced by the action of several microorganism mostly lactic acid, acetic acid bacteria and yeasts. This study included for using Kefir as immunomodulor to cell-mediate immune response ...
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Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression
... gens. Leishmania, a major protozoan parasite, is emerging as a new model for aneu- ploidy, since in vitro-cultivated strains are highly aneuploid, with interstrain diversity and intrastrain ...of Leishmania ...
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Role of the domestic dog as a reservoir host of Leishmania donovani in eastern Sudan
... the Leishmania donovani complex is one of the most important parasitic diseases, especially in Sudan, India and Nepal ...than Leishmania species causing VL in Sudan [5,6], but more recently molecular ...
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An integrated pipeline for the development of novel panels of mapped microsatellite markers for Leishmania donovani complex, Leishmania braziliensis and Leishmania major.
... All microsatellites on a chromosome or a region of a given chromosome that meet the following criteria set by the user can be extracted : chromosome, start position, end position, repeat unit length, minimum number of ...
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CRISPR Cas9 Mediated Genome Editing in Leishmania donovani
... to Leishmania donovani, a protozoan parasite that causes fatal human visceral ...L. donovani and generated guide RNA (gRNA) expression vectors by using the ...L. donovani rRNA promoter and the ...
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Evaluation of PCR procedures for detecting and quantifying Leishmania donovani DNA in large numbers of dried human blood samples from a visceral leishmaniasis focus in Northern Ethiopia
... for Leishmania k-DNA but most of those (69%) had less than 10 parasites/ml of ...were Leishmania donovani while two had ITS1 sequences homologous to Leishmania ...
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The Neurotrophic Receptor Ntrk2 Directs Lymphoid Tissue Neovascularization during Leishmania donovani Infection
... to Leishmania donovani-infected mice halted progressive vascular remodeling, reduced mononuclear phago- cyte (MP) number and improved the efficacy of immune-dependent drugs ...
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Killing of intracellular Leishmania donovani by lymphokine stimulated human mononuclear phagocytes Evidence that interferon gamma is the activating lymphokine
... Leishmania donovani, are rich in interferon (IFN)-gamma (600-3,000 U/ml). To determine the role of this specific lymphocyte product in macrophage activation, lymphokines were pretreated with a monoclonal ...
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Molecular Preadaptation to Antimony Resistance in Leishmania donovani on the Indian Subcontinent
... In a second stage, we looked at genome structure changes, more specifically somy and local copy number variations (CNVs), both known to occur when Leishmania is under selective pressure. The karyotype variability ...
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Xenodiagnosis of Leishmania donovani in BALB/c mice using Phlebotomus orientalis: a new laboratory model
... L. donovani infections in order to establish tools for study- ing the putative role of asymptomatic parasite carriers in the transmission dynamics of ...L. donovani with the capacity to heal visceralizing ...
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