Leucine zipper
A Putative Leucine Zipper within the Herpes Simplex Virus Type 1 UL6 Protein Is Required for Portal Ring Formation
... The leucine zipper mutants (D-LZ and L429E L436E mutants) map to the conserved helix ␣ 6; the leucine zipper which is present within this region in alphaher- pesviruses may be important in ...
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Homeobox leucine zipper proteins and cotton improvement
... associated leucine zipper proteins (HD-Zip) constitute a family of transcription factors that are characterized by the presence of a DNA- binding domain closely linked with leucine zipper ...
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Mutational analysis of the leucine zipper motif in the Newcastle disease virus fusion protein.
... the leucine zipper motif to the attack or host cell membrane suggests that this region may serve to penetrate the attack membrane during fusion in response to any conformational changes in the ectodomain of ...
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Glucocorticoid-induced leucine zipper (GILZ) in immuno suppression: master regulator or bystander?
... Induction of glucocorticoid-induced leucine zipper (GILZ) by glucocorticoids has been reported to be essential for their anti-inflammatory actions. At the same time, GILZ is actively downregulated under ...
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Investigation of the Multimerization Region of the Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Protein K-bZIP: the Proposed Leucine Zipper Region Encodes a Multimerization Domain with an Unusual Structure
... proposed leucine zipper region of K-bZIP is predicted to have a high probability of folding as a coiled coil, according to the analysis shown in ...the leucine zipper at “d” positions in the ...
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Amino Acid Substitutions within the Leucine Zipper Domain of the Murine Coronavirus Spike Protein Cause Defects in Oligomerization and the Ability To Induce Cell-to-Cell Fusion
... a leucine zipper motif, which is highly conserved among coronaviruses ...The leucine zipper motif, characterized as a sequence of leucine residues repeated every seven amino acids, was ...
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A Leucine Zipper Motif of a Tegument Protein Triggers Final Envelopment of Human Cytomegalovirus
... basic leucine zipper (bZIP)-like domain, which might serve as an oligomerization ...two leucine residues is sufficient to abrogate oligomerization but that intracellular localization of pUL71 was ...
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Both Neutralization Resistance and High Infectivity Phenotypes Are Caused by Mutations of Interacting Residues in the Human Immunodeficiency Virus Type 1 gp41 Leucine Zipper and the gp120 Receptor- and Coreceptor-Binding Domains
... In a previous study, we described HIV-1 neutralization es- cape mutants which were globally resistant to neutralization by all of a large number of HIV-1 antibody positive human sera tested with varied neutralizing ...
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Mutations in the leucine zipper of the human immunodeficiency virus type 1 transmembrane glycoprotein affect fusion and infectivity.
... To determine what role this region might play in envelope structure and function, several mutations were engineered into the middle isoleucine of the leucine zipper-like repeat of the hu[r] ...
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The Epstein-Barr virus Zta transactivator: a member of the bZIP family with unique DNA-binding specificity and a dimerization domain that lacks the characteristic heptad leucine zipper motif.
... The yeast transcription factor GCN4 also binds to the same consensus sequence, and all of these proteins fall into a superfamily of basic domain plus leucine zipper bZIP proteins with a [r] ...
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C-Terminal HIV-1 Transframe p6* Tetrapeptide Blocks Enhanced Gag Cleavage Incurred by Leucine Zipper Replacement of a Deleted p6* Domain
... FIG 2 The presence of four C-terminal p6* residues counteracts the leucine zipper enhancement effect on Gag processing. (A) Schematic representations of HIV-1 Gag and Gag-Pol expression constructs. HIV-1 ...
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Identification and expression of ventrally associated leucine zipper (VAL) in Xenopus embryo
... We performed in situ hybridization analysis to show the localization of cl. 162 transcript in embryogenesis. A small amount of transcript was first visible in the mid- gastrula embryo at the yolk plug region (Fig. 3 ...
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Evolution of Class III Homeodomain–Leucine Zipper Genes in Streptophytes
... homeodomain–leucine zipper (class III HD–Zip) genes, identified in the model plant Arabidopsis thaliana, provide good candidates for basic land plant patterning ...
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Structural Basis and DNA-binding Specificities of maf Basic Region-leucine Zipper Factors Suggest a Multistep Binding Mechanism.
... detectable in a gel shift by mixing the two proteins purified separately. MafA appeared to form a stable homodimer (FPLC size exclusion data not shown). Therefore we decided to test ATF2-MafA fusion proteins. In this way ...
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Targeted disruption of dual leucine zipper kinase and leucine zipper kinase promotes neuronal survival in a model of diffuse traumatic brain injury
... dual leucine zipper kinase (DLK/MAP3K12) and leucine zipper kinase (LZK/MAP3K13), the mitogen-activated protein kinase kinases (MAP2Ks) MKK4/MAP2K4 and MKK7/ MAP2K7, and the mitogen-activated ...
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A Conserved Leucine Zipper Motif in Gammaherpesvirus ORF52 Is Critical for Distinct Microtubule Rearrangements
... a leucine. Although not perfectly conserved, a third leucine is present in this relative position in most gamma- herpesvirus ORF52 orthologs, and when it is not present, the residue at this position is ...
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A role for the KP leucine zipper in regulating P element transposition in Drosophila melanogaster.
... This type of regulation is likely the result of a repressor protein that forms an inactive multimer with either transposase or with a host protein required for transposition [r] ...
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Stathmin involvement in the maternal embryonic leucine zipper kinase pathway in glioblastoma
... We analysed if MELK is upstream or downstream of STMN1 in the pathway, then we tested the expression of MELK and STMN1 using qRT-PCR and Western blot- ting in two conditions: before and [r] ...
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Mutational analysis of the leucine zipper-like motif of the human immunodeficiency virus type 1 envelope transmembrane glycoprotein.
... This highly conserved zipper motif, which consists of a heptad repeat of leucine or isoleucine residues, has been suggested to play a role in HIV-1 env glycoprotein oligomerization.. Thi[r] ...
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A baculovirus gene with a novel transcription pattern encodes a polypeptide with a zinc finger and a leucine zipper.
... 4489 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest An Autographa californica nuclear polyhedrosis virus gene encoding a 30-kilodalton polypeptide with two different s[r] ...
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