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Leukemia, B-Cell

Intraclonal Cell Expansion and Selection Driven by B Cell Receptor in Chronic Lymphocytic Leukemia

Intraclonal Cell Expansion and Selection Driven by B Cell Receptor in Chronic Lymphocytic Leukemia

... lymphocytic leukemia (CLL) clones defines two disease ...identical B cell receptors (BcR), often encoded by the same IG ...normal B cells together with the expression of stereotyped receptors ...

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Original Article CD317 is over-expressed in B-cell chronic lymphocytic leukemia, but not B-cell acute lymphoblastic leukemia

Original Article CD317 is over-expressed in B-cell chronic lymphocytic leukemia, but not B-cell acute lymphoblastic leukemia

... lymphoblastic leukemia (B-ALL) is a neoplasm of B cell precursors ...new B-ALL cases are diagnosed each year. 75% of B-ALL cases occur in children under six years of age ...[38]. ...

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The Role of PU.1 and Spi-B in B Cell Acute Lymphoblastic Leukemia

The Role of PU.1 and Spi-B in B Cell Acute Lymphoblastic Leukemia

... pediatric B cell acute lymphoblastic leukemia, representing 25% of the ...human leukemia cell lines AT-2 and REH, which express ETV6-RUNX1, suggested that SPIB was one of the top genes ...

88

Allogeneic cellular immunotherapy for chronic B-cell leukemia

Allogeneic cellular immunotherapy for chronic B-cell leukemia

... stimulator cell in two allogeneic ...T- cell lines and clones could be generated against MCL-APC, indicating that MCL-APCs are essential to induce an efficient anti-leukemic T-cell ...the ...

141

Case report: rare case of infiltration of small lymphocytic B-cell lymphoma in the thyroid gland of female patient with B-cell chronic lymphocytic leukemia (CLL-B/SLL-B)

Case report: rare case of infiltration of small lymphocytic B-cell lymphoma in the thyroid gland of female patient with B-cell chronic lymphocytic leukemia (CLL-B/SLL-B)

... lymphocytic B cell lymphoma in the thyroid ...lymphocytic B-cell leukemia diagnosed on the basis of histopathological examination of cervical lymph ...

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Acute B-Cell Lymphoblastic Leukemia/Acute B-Cell Lymphoblastic Lymphoma Presenting as Bilateral Breast Masses

Acute B-Cell Lymphoblastic Leukemia/Acute B-Cell Lymphoblastic Lymphoma Presenting as Bilateral Breast Masses

... Case Report: A thirty-year-old woman has applied to our department with a four month story of painless masses in both of breasts. We have performed tru-cut biopsies to both breasts after clinical examination. ...

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Residual normal B-cell profiles in monoclonal B-cell lymphocytosis versus chronic lymphocytic leukemia

Residual normal B-cell profiles in monoclonal B-cell lymphocytosis versus chronic lymphocytic leukemia

... Altogether, the above fi ndings suggest an impaired immune system and immune surveillance, already at very early CLL stages. So far, several immunological defects of both the innate and adaptive compartments of the immune ...

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Induction of human B cell antigens in non T cell acute lymphoblastic leukemia

Induction of human B cell antigens in non T cell acute lymphoblastic leukemia

... non-T cell ALL lines ...promyelocytic leukemia line or a T cell lymphoblastic leukemia ...non-T cell ALL lines, cytoplasmic mu-heavy chain (c mu) became undetectable, whereas the ...

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Metformin inhibits cell cycle progression of B-cell chronic lymphocytic leukemia cells

Metformin inhibits cell cycle progression of B-cell chronic lymphocytic leukemia cells

... Antibodies to surface proteins were CD44, CD54 (ICAM-1) and CD58 (LFA-3), CD62L and CXCR4(CD184), all from BD Pharmingen (San Diego, CA). Antibodies to intracellular proteins were rabbit polyclonal anti-Mcl-1 (H-260), ...

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Histiocytic sarcoma combined with acute monocytic leukemia: a case report

Histiocytic sarcoma combined with acute monocytic leukemia: a case report

... [3], B-cell acute lympho- blastic leukemia [8, 9, 11], and chronic lymphocytic leukemia [12], in which the HS was shown to share mo- lecular or cytogenetic features with associated ...germ ...

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Emerging roles of epithelial-mesenchymal transition in hematological malignancies

Emerging roles of epithelial-mesenchymal transition in hematological malignancies

... lymphoblastic leukemia; AML: Acute myeloid leukemia; BCL-6: B-cell lymphoma 6 protein; Bmi1: B cell-specific Moloney murine leukemia virus integration site 1; ChIP: ...

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High rates of submicroscopic aberrations in karyotypically normal acute lymphoblastic leukemia

High rates of submicroscopic aberrations in karyotypically normal acute lymphoblastic leukemia

... lymphoblastic leukemia; aMCB: Array-proven multicolor-banding; AML: Acute myelogenous leukemia; BAC: Bacterial artificial chromosome; B-ALL: B-cell ALL; Bp: Basepairs; CLL: Chronic ...

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www.ijcep.com /IJCEP1002005 Case Report An uncommon case of de novo CD10 CD5 mantle cell lymphoma mimics follicle center B cell lymphoma

www.ijcep.com /IJCEP1002005 Case Report An uncommon case of de novo CD10 CD5 mantle cell lymphoma mimics follicle center B cell lymphoma

... Despite the usual uniformity, cases of MCL with morphologic, immunophenotypic, genetic and clinical heterogeneity have been documented. Pleomorphic or blastoid variants of MCL usually have additional genetic changes and ...

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Case Report Splenic diffuse red pulp small B-cell lymphoma in an Asian female patient with review of literature

Case Report Splenic diffuse red pulp small B-cell lymphoma in an Asian female patient with review of literature

... HCL, leukemia cells in bone marrow have a typical “fried egg” pattern, and spleen morphology shows diffuse infiltration of the red pulp with hypoplastic white pulp and the char- acteristic blood lakes ...Mature ...

6

MYC as therapeutic target in leukemia and lymphoma

MYC as therapeutic target in leukemia and lymphoma

... Diffuse large B-cell lymphoma (DLBCL) is the most fre- quent subtype of mature B-cell lymphoma in western countries. MYC expression is detected in virtually all DLBCLs, but the number of ...

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CAR-T cells targeting CLL-1 as an approach to treat acute myeloid leukemia

CAR-T cells targeting CLL-1 as an approach to treat acute myeloid leukemia

... the B cell lineage marker CD19 has shown striking efficacy in treating CD19 + B cell ...cancer cell specificity that given the T cells greater capacity to recognize cells expressing low ...

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The Id-protein family in developmental and cancer-associated pathways

The Id-protein family in developmental and cancer-associated pathways

... supports cell proliferation ...consequent cell-cycle progression ...non-small cell lung cancer the activation of the Id1 gene promoter can be induced by nicotine and EGF in a Src-dependent manner, ...

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High levels of circulating soluble receptors for tumor necrosis factor in hairy cell leukemia and type B chronic lymphocytic leukemia

High levels of circulating soluble receptors for tumor necrosis factor in hairy cell leukemia and type B chronic lymphocytic leukemia

... and B titers were found to be elevated in almost all sera obtained from patients with underlying malignant ...with B cell malignancies including hairy cell leukemia (HCL) and type ...

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Hairy cell leukemia: A retrospective study on 11 patients in the Western of Iran.

Hairy cell leukemia: A retrospective study on 11 patients in the Western of Iran.

... Hairy cell leukemia (HCL) is a chronic B-cell lymphoid leukemia characterized by pancytopenia, splenomegaly, myelofibrosis and the presence in peripheral blood, bone marrow and spleen ...

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Combination of BCL11A siRNA with vincristine increases the apoptosis of SUDHL6 cells

Combination of BCL11A siRNA with vincristine increases the apoptosis of SUDHL6 cells

... B cell chronic lymphocytic leukemia/lymphoma 11 (BCL11) gene family members, including the BCL11A and BCL11B, have been identified as transcriptional repressors, which are essential for lymphoid ...

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