lgr6+ Stem cells
Lgr6+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors
... basal cells but left the overlying cell layers intact [12]. We stained for Lgr6+ stem cells, using an anti-EGFP antibody, in skin samples taken at different time points after UV overexposure; ...
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RNA-seq analysis of Lgr6(+) stem cells and identification of an Lgr6 isoform
... Lgr6-EGFP-Ires-CreERT2/R26R-LacZ transgenic mice (kindly provided by Prof. Hans Clevers) were backcrossed into a hairless background using Crl:SKH1-HR hairless mice (Charles River, Sulzfeld, Germany). Both ...
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Review Paper: Application of Hair Follicle Bulge Stem Cells in Wound Healing
... wounds, cells from the Interfol- licular Epidermis (IFE) and the hair follicles migrate into the damaged area [48, ...derived cells are involved in the re-epithelialization of epidermis in full- thickness ...
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Therapeutic use of stem cells for cardiovascular disease
... autologous cells. In vitro, MSCs co-cultured with immune cells upregulated the secretion of suppressive cytokines ...dendritic cells, T helper cells and macrophages ...these cells on a ...
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Cancer stem cell subsets and their relationships
... precancerous stem cells, meanwhile they have their unique ...cerous stem cells of DCIS exhibit different genotypes in contrast to primary cancer stem cells of IDC ...precancerous ...
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Stem Cell Therapy for Stroke, Recent Advances, Controversies and Literature Review
... embryonic stem cells where able to migrate along the corpus callosum towards the damaged tissue and differentiate into neurons in the border zone of the ...embryonic stem cells not only did ...
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Making gametes from alternate sources of stem cells: past, present and future
... dent stem cells. Based on recent advances on ovarian stem cells research, it is being understood that the niche gets disrupted by chemotherapy and also with age [103 – ...Resident stem ...
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Stem cell therapies for age-related macular degeneration: the past, present, and future
... RPE cells can be easily generated from several cell types (pluri- potent stem cells, multipotent stem cells, or even somatic cells) by spontaneous differentiation, coculturing, ...
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From regenerative dentistry to regenerative medicine: progress, challenges, and potential applications of oral stem cells
... G-CSF-treated DPSCs express a high level of trophic factors with properties of high proliferation, migration, and antiapop- totic effects and are endowed with regenerative potential. They transplanted G-CSF-mobilized ...
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Dental Stem Cells: Part of Regenerative Medicine
... transplanted into four littermate dogs (aged 28–40 days) by either arterial or muscular injections. Two noninjected dogs were kept in the control group. Then immune reac- tions were analyzed by blood investigations. ...
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Stem cells then, now and future!!
... progenitor cells might exist in the postnatal periodontal ligament has been recognized for some time but until recently had never been formally proven (Coura et ...These cells are believed to provide a ...
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Review Paper: Embryonic Stem Cell and Osteogenic Differentiation
... various stem cells, including embryonic stem cells (ESCs), bone marrow-derived mesenchymal stem cells (BM-MSCs), umbilical cord blood-derived mesenchymal stem cells ...
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Stem cells: a model for screening, discovery and development of drugs
... mesenchymal stem cells offer an attractive high throughput screening platform for new target/ drug ...These stem cells can be readily expanded in vitro and can be isolated from a variety of ...
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Role of FOXC1 in regulating APSCs self-renewal via STI-1/PrPC signaling
... glial cells that modulates astrocyte proliferation as an autocrine through PKC activation ...embryonic stem cells (ESCs) and thus implies an important role in pluripotency signaling ...neural ...
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Are Stem Cells the next Therapeutic Tool for Heart Repair?
... muscle cells and endothelial cells, which resulted in increased vascularity and im- proved cardiac function both at rest and under stress [ ...altered cells inhibited myocardial remodeling and ...
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STAT3, stem cells, cancer stem cells and p63
... cancer stem cell maintenance [13, ...epithelial cells via a ΔNp63 mechanisms ...neighboring cells to potentially promote ...cancer cells to acquire characteristic of tumor- initiating ...
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Stem Cell Therapy of Ischemic Heart Disease
... of cells in the sufficient amount for transplantation, and a possibility of application of both autologous and allogeneic MSC for elderly patients with comorbidities make MSC exceptionally attractive for the cell ...
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Mesenchymal stem cell-based cell-free strategies: safe and effective treatments for liver injury
... concentration varies from 1.13 to 1.19 g ml/L in sucrose solutions [49]. The nanometer-sized features made exo- somes easy to transfer through blood and other bio- logical fluids. The proteins and miRNAs contained in ...
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A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors
... that stem cells may be a rev- olutionary therapy for treatment of malignant brain tumors compared with traditional therapies of chemo- therapy, radiotherapy and ...of stem cell transplantation for ...
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Large animal models for stem cell therapy
... of cells, including skeletal myoblasts, bone marrow- and adipose tissue-derived stem cells, cardiac stem cells, and endothelial adult stem cells ...cardiac stem ...
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