While pauses, such as that experienced in January 2014, are a part of any healthy bull market, the structure of the pullback was still supportive of our thesis. The correction was led by larger capitalisation stocks, with sentiment holding up for smaller capitalisation names. This implies investors were happy to hold smaller stocks in the lead-up to reporting season, demonstrating some comfort in expectations.
Recently, RRC has been praised as an alternative to classic laparoscopic RC [12, 18]. CME allows for resec- tion along the unimpaired contour delineating the dorsal mesentery and the anatomo-embryological fusion fascias and is therefore vital for a true radical R0 resection, as the mesocolon contains the whole potential routes for local neoplastic spread through lympho-vascular, neuro- perineural and fibro-fatty tissues [3, 9, 19–21]. CVL fa- cilitates a comprehensive lymph node harvest along the supplying vessels paralleled by a relevant effect on re- gional recurrence and systemic dissemination [8, 22]. Lateral access is applied for open CME, during which the right colon is mobilized lateral to medial firstly along Toldt’s fascia; then, the visceral fascia is sharply dis- sected right sided along superior mesenteric vessels in order to expose and dissect the right colon-feeding ves- sels. In contrast, the laparoscopic CME to date applies a medial approach, during which the visceral peritoneum along the root of the right mesocolon is cut and lymph nodes liningup the surgical trunk are dissected firstly, followed by the seek and separation of Toldt fascia and ligation of the central vessels. Latter technique was ap- plied here in the MTL-group.
We propose a model to show that under off-normal bombardment of an incident ion beam, a solid surface may spontaneously form nanoscale dots liningup into chains perpendicular to the incident beam direction. These dots demonstrate a highly ordered hexagonal pattern. We attribute the self-organization behavior to surface instability under concurrent surface kinetics and to a shadow effect that causes the self-alignment of dots. The fundamental mechanism may be applicable to diverse systems, suggesting an effective approach for nanofabrication.
clay and refractory bricks means that the clay can be used for lining of heat treatment furnaces, melting furnaces for low melting point metals, liquid metal ladles and portions of blast furnaces. The percentage composition of impurities is generally below 0.2% while iron II Oxide account for 5.986% which is too high compared to specification for a refractory clay. The refractoriness is 1,300 0 C, which is below 1,500 0 C minimum requirement. This shows that there is low refractoriness of the clay content, low percentage of Aluminum Oxide (Al 2 O 3 ) and high percentage
The furnace lining is an inseparable and integral part of the chemical-thermal furnace ‘material-medium- lining’ of the system. Therefore, it should be considered only in conjunction with the other elements of the kiln system. In the rotary kiln lining, the skull is covered with a layer that provides protection against thermal radiation and the moving charge. The skull thickness must be supported on a constant level. If the surface temperature exceeds the value set by the technological requirements, the thickness of the skull is reduced, the lining is exposed, and the thermal conditions inside the furnace must be changed .
At least 11 different epithelial cell types have been identified in the conducting and respiratory portions of the lung . The basal, secretory, and ciliated cells are the major cell types constituting the pseudostratified epithelium of the proximal tracheobronchial area while AECI and AECII cells make up the alveolar epithelium . The onset of cell differentiation is signalled by various gene products including surfactant protein (SP)-A, SP-B, SP-C, SP-D and club (Clara) cells secretory protein (CCSP) [26–29]. During early embryonic development, the undifferentiated epithelium co- expresses several lineage markers including SP-A, CCSP and neuroendocrine cell markers. But later, during the pseudoglandular phase, this epithelium differentiates into different lineages and becomes restricted to proximal and distal airways . Transcriptional analysis reveals that the surfactant proteins and CCSP genes share common mechanisms for gene regulation and expression in respiratory epithelial cells. Nkx2.1 (also known as thyroid transcription factor-1 (TTF-1)), a homeodomain protein, plays a pivotal role in several phases of lung development, including epithelial cell lineage determination [31–34]. Nkx2.1 binds and activates SP-A, SP-B, SP-C, and CCSP promoter elements as well as Nkx2.1 itself [35–39]. During development of the respiratory epithelium, Nkx2.1 appears to be the earliest marker, with onset of expression at the time of lung bud formation from the foregut endoderm . Expression of Nkx2.1 is present throughout the foetal lung including respiratory epithelial cells of the trachea, bronchi, and developing respiratory tubules, but its expression is most robust in distal alveolar epithelium [24,40,41]. Null mutation of Nkx2.1 in mice exhibit tracheoesophageal fistulas and fail to form bronchiolar and alveolar structures [32–34]. Pulmonary-specific gene expression including SP-B, SP-C, and CCSP is extinguished within
Spray applied membranes may not be practical to install when high levels of water ingress through the substrate are expected. The waterproofing system approach based on anticipated water ingress through the primary sprayed concrete lining is summarised in Figure 2 below. The chart shows water ingress ranging from completely dry through to extensive water ingress throughout much of the tunnel primary lining surface. Spray applied membranes are deemed suitable for water ingress up to isolated areas with trickling or running water, or for tunnels treated with de-watering or pre- injection methods to control water ingress to manageable levels during construction. Tunnels that are substantially wet are ideally waterproofed with sheet membranes for example.
Fibroblast-like cells in the synovial lining (type B lining cells), stroma and pannus tissue are targeted by many signals, such as the following: ligands binding to cell surface receptors; lipid soluble, small molecular weight mediators (eg nitric oxide [NO], prostaglandins, carbon monoxide); extracellular matrix (ECM)–cell interactions; and direct cell–cell contacts, including gap junctional intercellular communication. Joints are subjected to cyclic mechanical loading and shear forces. Adherence and mechanical forces affect fibroblasts via the ECM (including the hyaluronan fluid phase matrix) and the pericellular matrix (eg extracellular matrix metalloproteinase inducer [EMMPRIN]) matrices, thus modulating fibroblast migration, adherence, proliferation, programmed cell death (including anoikis), synthesis or degradation of ECM, and production of various cytokines and other mediators . Aggressive, transformed or transfected mesenchymal cells containing proto-oncogenes can act in the absence of lymphocytes, but whether these cells represent regressed fibroblasts, chondrocytes or bone marrow stem cells is unclear.
Reactive oxygen and nitrogen species produced at chronic inflammatory sites may damage DNA. If the p53 gene itself gets damaged, apoptosis may be impaired. The p53 mutations are dominant negative and can interfere with endogenous wild-type p53 function . Significantly higher expression of p53 is detected in rheumatoid synovial tissues than in those tissues in patients with OA or reactive arthritis . Of inter- est, p53 was found in early RA and also in clinically uninvolved joints in RA patients . Yamanishi and colleagues  showed that abundant p53 transition mutations, which are characteristic of the DNA damage caused by oxidative stress, were located mainly in the lining tissues, in studies using microdissected rheumatoid synovial tissues. Considering these findings, mutant p53 may be over expressed in the mul- tilayered lining in group I, which fails to induce CASP9 and PIG11, while wild-type p53 in group II may induce these genes in group II.
Prior to the adoption of Ind AS, Indian-listed companies are required to apply existing Indian GAAP (Deloitte, 2015). In terms of para. 23 of Accounting Standard (AS) 19, the Indian GAAP standard on leases, companies are required to straight-line operating lease expenses unless another systematic is more representative of the time pattern of a user’s benefit (ICAI, 2014). This treatment is almost identical to that in IAS 17 para. 33 (IASB, 2012b) and has been retained in Ind AS 17 para. 33 (Ministry of Corporate Affairs, 2016), except that the latter also provides the further exception of recognising lease payments that are structured to increase with general inflation, on an as-incurred basis. By including the exception, it appears that under Ind AS the recognition of lease payment related to general inflation increases on an as-incurred basis is perceived to provide more value relevant information than when straight-lining those lease payments.
Abstract- Refractories refer to the heat resistant material and are widely used as the internal linings of furnaces, kilns, reactors and other vessels in the metallurgy industry. According to the chemical compositions, chromite is one of the neutral refractory. In this work, the chromite ore from Mwetaung area was used as raw material. Firstly, the chemical compositions and refractoriness were measured. The experimental works for chromite refractory materials for use in lining of induction furnace was carried out. To study the use of chromite raw material as induction furnace lining, five different sizes of chromite were mixed. Boric acid was used as binder. Cast iron and aluminium alloys were used as materials for melting. The lining was tested for a total of only (14) hours and (4) heat. After each test, the condition of the lining was studied and it was observed that no severe damage or erosion of the lining took place.
tunnels with various cross sections, its ability to model the different segmental arrangements, the lack of need for expensive laboratory tests or other experimental data, the capability of using different loading, as well as other facilities of modelling. For example, by comparing the results of continual and segmental linings, it can clearly be shown that the bending moment values in different parts of the tunnel lining have changed considerably, while the axial force values have not changed. Finally, it must be noted that all of the models in this research were applied to TUR tunnels site conditions; in other cases, a wider scope may need to be applied to research such as ignoring the circumferential joint effects and considering the effects of consecutive rings on each other, disregarding the special nature of segment junctions, as well as other modelling simplifications, some of which may considerably affect modelling results.