Lipid storage droplet-2
The role of lipid droplet formation in the protection of unsaturated fatty acids against palmitic acid induced lipotoxicity to rat insulin-producing cells
... of lipid droplets (LDs) by unsaturated NEFAs may be involved in the protection against lipotoxicity ...intracellular lipid storage [18, ...and 2 expression in rat ...
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Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes
... energy storage, but emerging research demonstrates a central role in intracellular signalling and adipokine ...type 2 diabetes and cardiovascular disease evident in ...
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Dynamics of the Lipid Droplet Proteome of the Oleaginous Yeast Rhodosporidium toruloides
... with lipid metabolism (Table 1), including synthesis and degrada- tion of fatty acid, TAG, and sterol ...information storage and processing, which was consistent with the results of a study on Drosophila ...
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Lipid droplet growth : regulation of a dynamic organelle
... contact sites to enable nascent LDs to acquire more lipids from the ER and grow to form mature LDs [12, 15]. SEIPIN also regulates the metabolism of phosphatidic acid (PA) at the LD-ER contact, acting as a scaffolding ...
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A New Patient of Chanarin Dorfman Syndrome in Egypt
... Chanarin Dorfman syndrome (CDS) is an autosomal recessive neutral lipid storage disorder characterized by ichthyosis, and multisystem affection. Here, we report another patient from Egypt. The clinical data ...
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Review Article Lipid droplet-associated proteins in alcoholic liver disease: a potential linkage with hepatocellular damage
... intracellular lipid droplets are coated with a phospholipid monolayer, on which many kinds of lipid droplet-associated proteins are ...in lipid metabolism in the physiological ...the ...
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A Novel Protein Kinase Localized to Lipid Droplets Is Required for Droplet Biogenesis in Trypanosomes
... the lipid droplet surface suggests it could function as a mediator of the lipidomic status in the cell, reminiscent of the sensing of AMP/ATP ratio by protein kinase ...the lipid droplet ...
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CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation
... GO cellular component, PANTHER and Reactome pathways in order to classify them by general biological function and pathway involved. Within GO biological processes (Fig. 4), the upregulated DE genes showed enrichment over ...
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Dynamic Morphologies and Stability of Droplet Interface Bilayers
... other lipid bilayer ...the lipid-in method [13,14] and to construct complex droplet networks [15 – ...from droplet arrays for ion channel screening [19,20] and chemical microreactors [21,22] ...
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Pulsatilla koreana Nakai Downregulates C/EBPs/PPAR-gamma and Suppresses Fatty Acid Synthase via activation of AMPK-alpha in 3T3-L1 cells
... culture plates. Differentiated 3T3-L1 cells were treated with PKEE at concentrations of 4, 20, and 100 μg/ml. Cells were washed twice with PBS and then fixed with 10 % neutral formalin for at least 20 min at room ...
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Genetics of Lipid-Storage Management in Caenorhabditis elegans Embryos
... and lipid metabolism (Byerly et ...examined lipid metabolism in adult worms (Ashrafi et ...embryo, lipid metabolism has been studied primarily with respect to the processing of yolk ...Further, ...
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Compression-induced dedifferentiation of adipocytes promotes tumor progression
... Another aspect of the present work is a new strategy to induce cellular reprogramming of adipocytes into multipotent cells termed CiDAs only mediated by local physical stresses. CiDAs are capable of long-term ...
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Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses
... Gene therapy has emerged as a potential treatment of lysosomal storage diseases. The viral vector can be injected intracranially into brain, resulting in the therapeutic effects of reducing lysosomal ...
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LRRK2 mediated Rab8a phosphorylation promotes lipid storage
... LRRK2 (leucine rich repeat kinase 2) has been a hot spot in the field of neurology as its mutations have been associ- ated with Parkinson’ s disease (PD) [14, 15]. PD is a com- mon neurodegenerative disease ...
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Water-gated organic nanowire transistors
... A thin film transistor (TFT) architecture has been widely used in particular with non conventional semiconductors, e.g. amorphous Si [1], organic semiconductors (OSCs) [2], and precursor route inorganic ...
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Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response
... Fig. 5 G0S2 promotes 53BP1 stability in glioma cells in response to radiation. a WB analyses of effect of G0S2 overexpression on γ -H2AX, Rad51, 53BP1 and PARP expression in response to IR. Arrow, cleaved PARP. b ...
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Viscosity effect on piezoelectric actuated nozzle in generating micro droplet
... the droplet size, droplet consistency and satellite ...The droplet generation process is empirical observation with operating parameters such as pulse shape, pulse amplitude and dwell ...The ...
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Chlamydomonas carries out fatty acid beta-oxidation in ancestral peroxisomes using a bona fide acyl-CoA oxidase
... understand lipid turnover processes in green microal- gae, we screened an insertional mutant library for strains perturbed in their capacity to remobilize oil ...the lipid droplet (LD) was observed ...
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Lipid coated liquid crystal droplets for the on chip detection of antimicrobial peptides
... Mono-disperse lipid-coated LC droplets of diameter ...the lipid mono- layer by the Smp43 was detected ( < 6 μ M) at concentrations well within its biologically active range, indi- cated by a dramatic ...
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RNA Interference Silencing of a Major Lipid Droplet Protein Affects Lipid Droplet Size in Chlamydomonas reinhardtii
... membrane lipid and neutral lipid ...for lipid droplet formation and turnover. Lipid droplets in animal cells are surrounded by a monolayer of phospholipids, and the availability of ...
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