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Lipidic cubic phase (LCP)

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

... The LCP-SFX data collected on sub-5 μm-sized crystals (Supplementary Figure 1a,b) at room temperature were of a reasonable quality to solve the structure by molecular replacement after application of an ...

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Hybrid delivery systems for methotrexate-lipidic liquid crystalline cubic phases and cubosomes with magnetic nanoparticles

Hybrid delivery systems for methotrexate-lipidic liquid crystalline cubic phases and cubosomes with magnetic nanoparticles

... liquid-crystalline lipidic cubic phase (LCP) that possesses a variety of desirable properties making them good candidates for drug delivery systems ...(DDS). LCP composed of monoolein ...

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Why GPCRs behave differently in cubic and lamellar lipidic mesophases

Why GPCRs behave differently in cubic and lamellar lipidic mesophases

... the lipidic cubic phase (LCP) as a suitable medium for growing high quality crystals of these proteins (see ref 1, and citations ...The LCP consists of a highly curved lipid bilayer ...

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Electrostatic swelling of bicontinuous cubic lipid phases

Electrostatic swelling of bicontinuous cubic lipid phases

... bicontinuous cubic phases have attracted enormous interest as bio-compatible sca ff olds for use in a wide range of applications including membrane protein crystallisation, drug delivery and ...bicontinuous ...

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Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes

Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes

... The lipidic cubic mesophase has been used to crystallize important membrane proteins for high-resolution structure ...meso- phase that grows crystals. Because the cubic phase is sticky ...

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Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes

Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes

... The lipidic cubic mesophase has been used to crystallize important membrane proteins for high-resolution structure ...meso- phase that grows crystals. Because the cubic phase is sticky ...

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Detergents Destabilize the Cubic Phase of Monoolein   Implications for Membrane Protein Crystallization

Detergents Destabilize the Cubic Phase of Monoolein Implications for Membrane Protein Crystallization

... a lipidic cubic phase as the hosting medium. The cubic phase provides a lipid bilayer into which the protein presumably reconstitutes and from which protein crystals nucleate and ...

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Crystallizing membrane proteins for structure function studies using lipidic mesophases

Crystallizing membrane proteins for structure function studies using lipidic mesophases

... The lipidic cubic phase method for crystallizing membrane proteins has posted some high-profile successes ...viscous cubic mesophase in which crystals ...

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Structural and Electronic Properties of Bixo3  (X = Mn, Fe, Cr)

Structural and Electronic Properties of Bixo3 (X = Mn, Fe, Cr)

... magnetic and ferroelectric respectively. With structural distortions driven by the strongly polarizable Bi ions, we present results of the first-principles density functional calculations using the (FP-LMTO) method with ...

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Nanoparticle-Embedded Polymer: Preparation and Characterization of PVA-PPy-Au Nanocomposite Free Standing Films

Nanoparticle-Embedded Polymer: Preparation and Characterization of PVA-PPy-Au Nanocomposite Free Standing Films

... Cubosomes are allowed to form or crystallize from precursors. The formation of Cubosomes by dispersing L2 or inverse micellar phase droplets in water at 80°C, and allow them to cool slowly, gradually droplets get ...

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Phase Transformations Induced by Severe Plastic Deformation

Phase Transformations Induced by Severe Plastic Deformation

... second phase contains few monolayers of a second ...“hard” phase leads to a kind of lubricating during GB ...solid phase can form before HPT the continous layers in GBs of a matrix (so-called ...

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Comparative Study between the Role of Medial LCP and Anterolateral LCP in the Management of Fractures of Distal Tibia

Comparative Study between the Role of Medial LCP and Anterolateral LCP in the Management of Fractures of Distal Tibia

... Background As the civilisation proceeds towards industrialisation more and more accidents have been experienced. In almost all over the world, the incidence of road traffic and industrial accidents are growing up, ...

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Residual Stress, Phase, Microstructure and Mechanical Property Enhancement of Ultrafine Bainitic Steel through Laser Shock Processing

Residual Stress, Phase, Microstructure and Mechanical Property Enhancement of Ultrafine Bainitic Steel through Laser Shock Processing

... The study proposes laser shock peening without a coating of high strength ultrafine bainitic steel to mitigating the fatigue failures for automotive and structural engineering applications. Laser pulse density of 2500 ...

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The temperature composition phase diagram of monomyristolein in water: equilibrium and metastability aspects

The temperature composition phase diagram of monomyristolein in water: equilibrium and metastability aspects

... Undercooled cubic phases Several hydrated lipid samples, at equilibrium in either the Ia3d or Pn3m cubic phase, were cooled to and incubated at a temperature that, under equilibrium cond[r] ...

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Why is the Liverpool care pathway used for some dying cancer patients and not others? Healthcare professionals' perspectives.

Why is the Liverpool care pathway used for some dying cancer patients and not others? Healthcare professionals' perspectives.

... hospital ward. Summary narratives were compiled for each case. The data were then revisited and thematically organised and analysed [18]. This involved developing a thematic framework by identifying key issues and con- ...

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Why is the Liverpool care pathway used for some dying cancer patients and not others? Healthcare professionals’ perspectives

Why is the Liverpool care pathway used for some dying cancer patients and not others? Healthcare professionals’ perspectives

... hospital ward. Summary narratives were compiled for each case. The data were then revisited and thematically organised and analysed [18]. This involved developing a thematic framework by identifying key issues and con- ...

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Model of Cubic Cell for Description of Some Phase Transitions in Crystals

Model of Cubic Cell for Description of Some Phase Transitions in Crystals

... on phase transitions, Frenkel elaborated a three-atomic model, built from three identical atoms, placed on a straight ...a cubic model, where the summits occupy immovable atoms and the atom in the inner ...

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Role of configurational entropy in body-centred cubic or face-centred cubic phase formation in high entropy alloys

Role of configurational entropy in body-centred cubic or face-centred cubic phase formation in high entropy alloys

... comparative phase stability of transition and late transition element based high entropy alloys in body-centred cubic (BCC) or face-centred cubic (FCC) forms using a combined classical molecular ...

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Renaturing membrane proteins in the lipid cubic phase, a nanoporous membrane mimetic

Renaturing membrane proteins in the lipid cubic phase, a nanoporous membrane mimetic

... bicontinuous cubic phase as an extremely versatile and useful nano- porous membrane mimetic that can double as a chaperonin to mit- igate aggregation and as a receptacle into which the membrane protein can ...

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An Anion-Induced Hydrothermal Oriented-Explosive Strategy for the Synthesis of Porous Upconversion Nanocrystals

An Anion-Induced Hydrothermal Oriented-Explosive Strategy for the Synthesis of Porous Upconversion Nanocrystals

... the cubic phase, the hexagonal phase is more thermodynamically ...hexagonal phase are difficult to be acquired within the nanometer ...higher phase transition energy barrier shown in ...

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